Retinal vessel segmentation via Iterative Geodesic Time Transform

Accurate vessel segmentation is the first step in retinal image analysis for medical diagnosis. In this paper we propose a novel method to segment vessel network in fundus image. Vessel centerlines are first extracted by using a set of directional line detectors. Next an Iterative Geodesic Time Transform (ItGTT) is designed to segment the entire vessel network. The idea of the ItGTT is to use centerline pixels as the initial reference set, and compute geodesic time between candidate vessel pixels and the reference set iteratively with an adaptive reference set updating strategy. The entire vessel network is the binary image of the last reference set at the end of the iteration. Experimental results demonstrate that our method can segment retinal vessels effectively.

[1]  Ana Maria Mendonça,et al.  Segmentation of retinal blood vessels by combining the detection of centerlines and morphological reconstruction , 2006, IEEE Transactions on Medical Imaging.

[2]  Pierre Soille,et al.  Morphological Image Analysis: Principles and Applications , 2003 .

[3]  Pierre Soille,et al.  Edge-preserving smoothing using a similarity measure in adaptive geodesic neighbourhoods , 2009, Pattern Recognit..

[4]  M. Goldbaum,et al.  Detection of blood vessels in retinal images using two-dimensional matched filters. , 1989, IEEE transactions on medical imaging.

[5]  Roberto Marcondes Cesar Junior,et al.  Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification , 2005, IEEE Transactions on Medical Imaging.

[6]  Xiaoyi Jiang,et al.  Adaptive Local Thresholding by Verification-Based Multithreshold Probing with Application to Vessel Detection in Retinal Images , 2003, IEEE Trans. Pattern Anal. Mach. Intell..

[7]  David Zhang,et al.  Palm line extraction and matching for personal authentication , 2006, IEEE Transactions on Systems, Man, and Cybernetics - Part A: Systems and Humans.

[8]  Radford M. Neal Pattern Recognition and Machine Learning , 2007, Technometrics.

[9]  Evangelos Dermatas,et al.  Multi-scale retinal vessel segmentation using line tracking , 2010, Comput. Medical Imaging Graph..

[10]  M. Cree,et al.  Automated Image Detection of Retinal Pathology , 2009 .

[11]  Zeev Farbman,et al.  Edge-preserving decompositions for multi-scale tone and detail manipulation , 2008, SIGGRAPH 2008.

[12]  Geir E. Øien,et al.  Diabetic retinopathy : Automatic detection of earlysymptoms from retinal , 1995 .

[13]  Max A. Viergever,et al.  Ridge-based vessel segmentation in color images of the retina , 2004, IEEE Transactions on Medical Imaging.