Guidelines for management of asthma

papillary necrosis. Such patients will not present with renal failure if the contralateral kidney functions normally, and under these circumstances the diagnosis of an obstructed pyonephrosis can easily be delayed, with potentially serious consequences for renal function. If acute obstruction is suspected in the presence of infection a negative ultrasonogram is of no clinical value (and, as Dr Webb implies, a dilated collecting system will require further evaluation by other means). Such patients deserve urography, and if this shows a "non-functioning" kidney antegrade pyelography should be carried out, which can be followed by percutaneous drainage if obstruction is present. STEPHEN J AUSTIN

[1]  P. Rees Guidelines for the management of asthma in adults. , 1990, BMJ.

[2]  E. Robin,et al.  Death from bronchial asthma. , 1988, Chest.

[3]  T. Higenbottam,et al.  HAS THE MANAGEMENT OF ASTHMA IMPROVED? , 1987, The Lancet.

[4]  G. Hedlin,et al.  Immunotherapy with partially purified and standardized animal dander extracts. I. Clinical results from a double-blind study on patients with animal dander asthma. , 1986, The Journal of allergy and clinical immunology.

[5]  J. Bousquet,et al.  Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. I. In vivo and in vitro parameters after a short course of treatment. , 1985, The Journal of allergy and clinical immunology.

[6]  S. Findlay,et al.  Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of in vivo and in vitro responses. , 1984, The Journal of allergy and clinical immunology.

[7]  J. Collins,et al.  Assessment and management of acute asthma in the elderly: a comparison with younger asthmatics , 1982, Postgraduate medical journal.

[8]  F. C. Lowell,et al.  Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of bronchial responses to cat allergen and histamine. , 1978, The Journal of allergy and clinical immunology.

[9]  R. Vestal,et al.  Reduced Awareness of Methacholine-Provoked Bronchoconstriction in Elderly Asthmatics and Normals , 1990 .

[10]  G. Hedlin,et al.  Immunotherapy with cat- and dog-dander extracts. IV. Effects of 2 years of treatment. , 1989, The Journal of allergy and clinical immunology.

[11]  A. Kagey‐Sobotka,et al.  Immunotherapy decreases skin sensitivity to cat extract. , 1989, The Journal of allergy and clinical immunology.