p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest.

[1]  J. Pietenpol,et al.  MECHANISMS OF CELL-CYCLE CHECKPOINTS: AT THE CROSSROADS OF CARCINOGENESIS AND DRUG DISCOVERY* , 2000, Drug metabolism reviews.

[2]  R. von Harsdorf,et al.  p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c‐independent apoptosis blocked by Bcl‐2 , 1999, The EMBO journal.

[3]  T. Myers,et al.  Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin , 1999, Molecular and Cellular Biology.

[4]  S. Leach,et al.  p21Waf1/Cip1 Inhibition of Cyclin E/Cdk2 Activity Prevents Endoreduplication after Mitotic Spindle Disruption , 1999, Molecular and Cellular Biology.

[5]  K. Kinzler,et al.  Requirement for p53 and p21 to sustain G2 arrest after DNA damage. , 1998, Science.

[6]  A. Giaccia,et al.  The complexity of p53 modulation: emerging patterns from divergent signals. , 1998, Genes & development.

[7]  L. Bracco,et al.  The requirement for the p53 proline‐rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression , 1998, The EMBO journal.

[8]  J. Pietenpol,et al.  Differential cell cycle checkpoint response in normal human keratinocytes and fibroblasts. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[9]  A. Jaiswal,et al.  Disruption of the DT Diaphorase (NQO1) Gene in Mice Leads to Increased Menadione Toxicity* , 1998, The Journal of Biological Chemistry.

[10]  P. Rangarajan,et al.  Involvement of p85 in p53-dependent apoptotic response to oxidative stress , 1998, Nature.

[11]  K. Kinzler,et al.  14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression , 1997 .

[12]  L. Gudas,et al.  Human breast cancer cells and normal mammary epithelial cells: retinol metabolism and growth inhibition by the retinol metabolite 4-oxoretinol. , 1997, Cancer research.

[13]  K. Kinzler,et al.  A model for p53-induced apoptosis , 1997, Nature.

[14]  John Calvin Reed,et al.  Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria , 1996, Cell.

[15]  V. Ferrans,et al.  Reactive oxygen species are downstream mediators of p53-dependent apoptosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[16]  D. Ross,et al.  Quinone-induced apoptosis in human colon adenocarcinoma cells via DT-diaphorase mediated bioactivation. , 1996, Chemico-biological interactions.

[17]  K. Kinzler,et al.  p21 is necessary for the p53-mediated G1 arrest in human cancer cells. , 1995, Cancer research.

[18]  S. Velasco-Miguel,et al.  Induction of the growth inhibitor IGF-binding protein 3 by p53 , 1995, Nature.

[19]  James Brugarolas,et al.  Radiation-induced cell cycle arrest compromised by p21 deficiency , 1995, Nature.

[20]  Stephen J. Elledge,et al.  Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control , 1995, Cell.

[21]  John Calvin Reed,et al.  Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.

[22]  P. O'Connor,et al.  Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. , 1994, Oncogene.

[23]  K. Kinzler,et al.  Sequence-specific transcriptional activation is essential for growth suppression by p53. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Yi-Song Wang,et al.  WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. , 1994, Cancer research.

[25]  David Beach,et al.  p21 is a universal inhibitor of cyclin kinases , 1993, Nature.

[26]  M. Scheffner,et al.  The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 , 1993, Cell.

[27]  Kathleen R. Cho,et al.  Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[28]  K. Kinzler,et al.  Definition of a consensus binding site for p53 , 1992, Nature Genetics.

[29]  J. Zigler,et al.  Identification and characterization of the enzymatic activity of zeta-crystallin from guinea pig lens. A novel NADPH:quinone oxidoreductase. , 1992, The Journal of biological chemistry.

[30]  K. Kinzler,et al.  Identification of p53 as a sequence-specific DNA-binding protein , 1991, Science.

[31]  P. Blumberg,et al.  Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts , 1976, Nature.

[32]  I. Krantz,et al.  KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene , 1997, Nature Genetics.

[33]  G. Powis,et al.  Metabolism and reactions of quinoid anticancer agents. , 1987, Pharmacology & therapeutics.

[34]  M. Berger,et al.  Use of quinones in brain-tumor therapy: preliminary results of preclinical laboratory investigations. , 1985, Journal of toxicology and environmental health.