The use of solubility parameters in pharmaceutical dosage form design

The use and potential of solubility parameters for pharmaceutical dosage form design are reviewed in this paper. Specific reference is given to the development of the approach, its previous usage and likely future applications. The advantages, assumptions and limitations of this type of approach are also described.

[1]  D. H. Kaelble,et al.  A surface energy analysis of bioadhesion , 1977 .

[2]  A. Stamm,et al.  Quantitative Evaluation of the Wettability of Powders , 1984 .

[3]  K. C. James,et al.  The solubilities of the lower testosterone esters , 1968, The Journal of pharmacy and pharmacology.

[4]  P. York CRYSTAL ENGINEERING AND PARTICLE DESIGN FOR THE POWDER COMPACTION PROCESS , 1992 .

[5]  R. Rowe Binder-substrate interactions in tablets: a theoretical approach based on solubility parameters , 1988 .

[6]  P Bustamante,et al.  Partial solubility parameters and solvatochromic parameters for predicting the solubility of single and multiple drugs in individual solvents. , 1993, Journal of pharmaceutical sciences.

[7]  S. R. Bakalyar,et al.  Solvent selectivity in reversed-phase high-pressure liquid chromatography , 1977 .

[8]  M. A. LaPack,et al.  The correlation of membrane permselectivity with Hildebrand solubility parameters , 1994 .

[9]  C. A. Smolders,et al.  The determination of solubility parameters of solvents and polymers by means of correlations with other physical quantities , 1975 .

[10]  G. Buckton Contact angle, adsorption and wettability — a review with respect to powders , 1990 .

[11]  A. Paruta,et al.  Correlation between solubility parameters and dielectric constants. , 1962, Journal of pharmaceutical sciences.

[12]  R. Rowe Interaction of lubricants with microcrystalline cellulose and anhydrous lactose — a solubility parameter approach , 1988 .

[13]  R. Rowe,et al.  An evaluation of the plasticizing efficiency of the dialkyl phthalates in ethyl cellulose films using the torsional braid pendulum , 1984 .

[14]  A. Willbourn,et al.  Molecular design of polymers , 1976 .

[15]  L. Lee Relationships between surface wettability and glass temperatures of high polymers , 1968 .

[16]  N. L. Salmén,et al.  The influence of water on the glass transition temperature of cellulose , 1977 .

[17]  T. A. Kavassalis,et al.  Estimation of Hansen Solubility Parameters for (Hydroxyethyl) and (Hydroxypropyl) cellulose through Molecular Simulation , 1994 .

[18]  R. Rowe,et al.  The solubility parameter and fractional polarity of microcrystalline cellulose as determined by mechanical measurement , 1993 .

[19]  M. B. James,et al.  The influence of physical properties of the materials in contact on the adhesion strength of particles of salmeterol base and salmeterol salts to various substrate materials , 1996 .

[20]  H. Furukawa,et al.  Relationship between molecular structure and deformation-fracture mechanism of amorphous polymers: 2. Crazing stress , 1995 .

[21]  S. Young,et al.  Particle growth in aqueous suspensions: the influence of surface energy and polarity , 1990 .

[22]  G. Zografi,et al.  Wettability of pharmaceutical solids: estimates of solid surface polarity. , 1976, Journal of pharmaceutical sciences.

[23]  B. Escalera,et al.  A Modification of the Extended Hildebrand Approach to Predict the Solubility of Structurally Related Drugs in Solvent Mixtures , 1993, The Journal of pharmacy and pharmacology.

[24]  R. Rowe Interactions in coloured powders and tablet formulations: a theoretical approach based on solubility parameters , 1989 .

[25]  R. C. Little Some physical properties of soap/solvent systems and their relation to the solubility parameter of the solvent , 1966 .

[26]  A. Munafo,et al.  Determination of partial solubility parameters of lactose by gas-solid chromatography. , 1986, Journal of pharmaceutical sciences.

[27]  P. York,et al.  The relationship between the fracture properties, tensile strength and critical stress intensity factor of organic solids and their molecular structure , 1995 .

[28]  R. Rowe Interactions in the ternary powder system microcrystalline cellulose, magnesium stearate and colloidal silica —a solubility parameter approach , 1988 .

[29]  R. Rowe Polar/non-polar interactions in the granulation of organic substrates with polymer binding agents , 1989 .

[30]  P. Noyce,et al.  Solubilities of testosterone propionate and related esters in organic solvents. , 1976, Journal of pharmaceutical sciences.

[31]  A. Adjei,et al.  Extended Hildebrand approach: solubility of caffeine in dioxane-water mixtures. , 1980, Journal of pharmaceutical sciences.

[32]  A. Adjei,et al.  Extended Hildebrand solubility approach: solubility of theophylline in polar binary solvents. , 1980, Journal of pharmaceutical sciences.

[33]  P. Ruelle,et al.  A new equation for calculating partial cohesion parameters of solid substances from solubilities , 1988 .

[34]  S. Khalil,et al.  Drug transport through model membranes and its correlation with solubility parameters. , 1967, Journal of pharmaceutical sciences.

[35]  P. York,et al.  The relationship between indentation hardness of organic solids and their molecular structure , 1994, Journal of Materials Science.

[36]  C. Hansen,et al.  The Universality of the Solubility Parameter , 1969 .

[37]  A. Barton Applications of solubility parameters and other cohesion parameters in polymer science and technology , 1985 .

[38]  A. Beezer,et al.  The Effect of the Comminution Technique on the Surface-Energy of a Powder , 1988 .

[39]  A. M. Bochek,et al.  Cellulose solubility parameters , 1993 .

[40]  P. York,et al.  The relationship between Young's modulus of elasticity of organic solids and their molecular structure , 1991 .

[41]  J. King Determination of the Solubility Parameter of Soybean Oil by Inverse Gas Chromatography , 1995 .

[42]  R. Rowe Interactions in powders and granules — a reappraisal , 1992 .

[43]  Joel H. Hildebrand,et al.  The solubility of nonelectrolytes , 1964 .

[44]  G. Buckton The estimation and application of surface energy data for powdered systems , 1992 .

[45]  Experimentally optimized determination of the partial and total cohesion parameters of an insoluble polymer (microcrystalline cellulose) by gas-solid chromatography , 1987 .

[46]  G. Roberts,et al.  Determination of the solubility parameter of o-hydroxypropyl cellulose , 1978 .

[47]  A. Martin,et al.  SOLUBILITY OF BENZOIC ACID AND RELATED COMPOUNDS IN A SERIES OF ETA-ALKANOLS. , 1964, Journal of pharmaceutical sciences.

[48]  R. Rowe,et al.  The solubility parameters of some cellulose derivatives and polyethylene glycols used in tablet film coating , 1986 .

[49]  George Zografi,et al.  The molecular basis of moisture effects on the physical and chemical stability of drugs in the solid state , 1990 .

[50]  C. Hansen,et al.  The Three Dimensional Solubility Parameter-Key to Paint Component Affinities : II. Dies, Emulsifiers, Mutual Solubility and Compatibility, and Pigments , 1967 .

[51]  R. Rowe,et al.  Interactions in cellulose derivative films for oral drug delivery , 1995 .

[52]  C. Vaughan Using solubility parameters in cosmetics formulation , 1985 .

[53]  R. C. Rowe Expert systems in solid dosage development , 1993 .

[54]  L. Snyder,et al.  Expanded solubility parameter treatment for classification and use of chromatographic solvents and adsorbents , 1976 .

[55]  W. Archer Hansen solubility parameters for selected cellulose ether derivatives and their use in the pharmaceutical industry , 1992 .

[56]  C. Sunwoo,et al.  Solubility parameter of selected sulfonamides. , 1971, Journal of pharmaceutical sciences.

[57]  J. Newton,et al.  The influence of processing variables on the wetting properties of a hydrophobic powder , 1980 .

[58]  G. Zografi,et al.  Adhesion of hydroxypropyl cellulose films to low energy solid substrates. , 1986, Journal of pharmaceutical sciences.

[59]  Alfred N. Martin,et al.  The Solubility of Benzoic Acid in Mixed Solvents , 1960 .

[60]  J. Fell,et al.  Bonding mechanisms in tabletting , 1990 .

[61]  D. V. Krevelen,et al.  Properties of polymers, their estimation and correlation with chemical structure , 1972 .

[62]  E. Yonemochi,et al.  Solubility Parameter and Dissolution Behavior of Cefalexin Powders with Different Crystallinity , 1992 .

[63]  R. Rowe,et al.  Solubility studies on ethyl cellulose used in film coating , 1978, The Journal of pharmacy and pharmacology.

[64]  Allan F. M. Barton,et al.  CRC Handbook of solubility parameters and other cohesion parameters , 1983 .

[65]  J. Nairn,et al.  Solubility parameter effects on microencapsulation in the presence of polyisobutylene , 1994 .

[66]  S. Yalkowsky,et al.  Importance of chain length on physicochemical and crystalline properties of organic homologs. , 1972, Journal of pharmaceutical sciences.

[67]  P. York,et al.  Determination of the surface properties of two batches of salbutamol sulphate by inverse gas chromatography , 1994 .

[68]  R. C. Rowe,et al.  AN EXPERT SYSTEM FOR THE IDENTIFICATION AND SOLUTION OF FILM-COATING DEFECTS , 1993 .

[69]  J. L. Gardon Critical review of concepts common to cohesive energy density, surface tension, tensile strength, heat of mixing, interfacial tension and butt joint strength , 1977 .

[70]  A. Paruta,et al.  Extended Hildebrand Solubility Approach: methylxanthines in mixed solvents. , 1981, Journal of pharmaceutical sciences.

[71]  R. Rowe The prediction of compatibility/incompatibility in blends of ethyl cellulose with hydroxypropyl methylcellulose or hydroxypropyl cellulose using 2‐dimensional solubility parameter maps , 1986, The Journal of pharmacy and pharmacology.

[72]  R. Rowe Adhesion of film coatings to tablet surfaces —a theoretical approach based on solubility parameters , 1988 .