Heart rate at baseline influences the effect of ivabradine on cardiovascular outcomes in chronic heart failure: analysis from the SHIFT study

[1]  K. Swedberg,et al.  Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy , 2011, European heart journal.

[2]  M. Gold,et al.  Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial , 2011 .

[3]  R. Ferrari,et al.  Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling. , 2011, American journal of physiology. Heart and circulatory physiology.

[4]  Ankur Gupta,et al.  Ivabradine and outcomes in chronic heart failure , 2010, The Lancet.

[5]  U. Laufs,et al.  Vascular pathophysiology in response to increased heart rate. , 2010, Journal of the American College of Cardiology.

[6]  K. Swedberg,et al.  Rationale and design of a randomized, double‐blind, placebo‐controlled outcome trial of ivabradine in chronic heart failure: the Systolic Heart Failure Treatment with the If Inhibitor Ivabradine Trial (SHIFT) , 2010, European journal of heart failure.

[7]  Michael Böhm,et al.  Heart rate reduction in cardiovascular disease and therapy , 2010, Clinical Research in Cardiology.

[8]  M. Böhm,et al.  Heart rate reduction by I(f)-channel inhibition and its potential role in heart failure with reduced and preserved ejection fraction. , 2009, Trends in cardiovascular medicine.

[9]  U. Laufs,et al.  Heart Rate Reduction by Ivabradine Reduces Oxidative Stress, Improves Endothelial Function, and Prevents Atherosclerosis in Apolipoprotein E–Deficient Mice , 2008, Circulation.

[10]  C. Pepine,et al.  Impact of resting heart rate on outcomes in hypertensive patients with coronary artery disease: findings from the INternational VErapamil-SR/trandolapril STudy (INVEST). , 2007, European heart journal.

[11]  Jean-Claude Tardif,et al.  Long-term prognostic value of resting heart rate in patients with suspected or proven coronary artery disease. , 2005, European heart journal.

[12]  F. Lallemand,et al.  Long-Term Heart Rate Reduction Induced by the Selective If Current Inhibitor Ivabradine Improves Left Ventricular Function and Intrinsic Myocardial Structure in Congestive Heart Failure , 2004, Circulation.

[13]  L. Hittinger,et al.  Effect of Graded Heart Rate Reduction with Ivabradine on Myocardial Oxygen Consumption and Diastolic Time in Exercising Dogs , 2004, Journal of Pharmacology and Experimental Therapeutics.

[14]  N Freemantle,et al.  The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis. , 2003, European heart journal.

[15]  D. DiFrancesco,et al.  Current-dependent Block of Rabbit Sino-Atrial Node If Channels by Ivabradine , 2002, The Journal of general physiology.

[16]  G. Hasenfuss,et al.  Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy. , 1994, European heart journal.

[17]  G. Radda,et al.  Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy , 1991, The Lancet.