Traitement des variabilités métier dans les Systèmes d'Information biologiques

Scientific information systems require consideration of two types of variability: variability between actors and variability between studies. We treated the variability between actors in a data import system that guarantees data quality and the variability between studies by the use of an annotation mechanism. To control high quality data when importing information from different actors, we propose an approach based on two levels of knowledge: 1) knowledge in the IS is represented by models and their implementation. They guarantee the completeness and consistency of data in the IS; 2) domain knowledge is represented by an application ontology. eClims system which implements these two mechanisms is described. MOTS-CLES : connaissance evolutive, importation de donnees, annotation, SI biologique