论文信息 - Synthesis of optically active substituted cyclohexenones from carbohydrates by catalytic Ferrier rearrangement

Synthesis of optically active substituted cyclohexenones from carbohydrates by catalytic Ferrier rearrangement

Conversion of hex-5-enopyranosides into substituted cyclohexanones (Ferrier rearrangement) was found to proceed efficiently with a catalytic amount of various mercury(II) salts at room temperature in a neutral solvent system. Among the mercury(II) salts tested, mercury(II) trifluoroacetate showed the highest activity. Four optically active cyclohexenones were prepared from hex-5-enopyranosides utilizing this method.

N. Chida | M. Ohtsuka | S. Ogawa | K. Ogura

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