Prolactinomas apparently resistant to quinagolide respond to cabergoline therapy.

patientswithelevatedcalcitoninlevelswerefoundtohavedifferentiatedthyroidcarcinoma,whichmightbeexplainedbyCcellhyperplasiaadjacenttoafollicularorpapillarycarcinoma.Wewouldliketoaddanotherunexpectedyieldofserumcalcitoninmeasurement:thepossi-bilityofconcurrentmedullaryandpapillarythyroidcarcinomas.Weherereportacaseof59-yr-oldwomanpresentingwithright thyroid nodule. She had no family history of thyroid diseases. Both serum calcitonin and carcinoembryonic antigen (CEA) levels were in-creased (2000 pg/mL and 14.3 ng/mL, respectively), whereas thyro-globulinwasnormal(11.5ng/mL).Furtherexaminations,includingfineneedleaspirationand 131 I-meta-iodobenzylguanidine scintigraphy, in-dicated a diagnosis of medullary thyroid carcinoma, and total thyroid- ectomy with bilateral central and right modified neck dissection was performed. Both serum calcitonin and CEA levels decreased to normal range after the operation. Pathological examinations of the resected specimen showed several foci of follicles with ground glass-like nucleus, which were surrounded by medullary carcinoma tissue. Both intrathy-roidal lesion and metastatic lymph node tissue showed positive staining for both thyroglobulin and calcitonin. Therefore the diagnosis of concurrent medullary and papillary carcinomas was made. Coexistence of medullary and papillary carcinomas has been,