Conditional deletion of Abca 3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice

Valérie Besnard,* Yohei Matsuzaki,* Jean Clark, Yan Xu, Susan E. Wert, Machiko Ikegami, Mildred T. Stahlman, Timothy E. Weaver, Alan N. Hunt, Anthony D. Postle, and Jeffrey A. Whitsett The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics and University of Cincinnati College of Medicine, Cincinnati, Ohio; Department of Pediatrics, School of Medicine, Keio University, Tokyo, Japan; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee; and Division of Infection, Inflammation, and Immunity, School of Medicine, University of Southampton, Southampton, United Kingdom

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