Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II.
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Yuanfeng Wu | Likun Gong | Yan Li | Yang Luan | X. Qi | Ming Li | X. Xue | Xiong-fei Wu | Min Chen | Guo-zhen Xing | Jun Yao | Jin Ren | Xiang Xue