Standardization of body surface area calculations

Purpose. Antineoplastic agents have a narrow therapeutic index and therefore require the greatest degree of dose individualization. In choosing a body surface area (BSA) for‘mula, the challenge remains in obtaining consensus among prescribers. The objective of this review is to assess the various formulae available for calculating BSA and to adopt a standard formula within an institution.Methods. Retrospective review of medication orders containing the patient’s height and weight as well as BSA calculated by the outpatient clinic staff within the Cross Cancer Institute (CCI) from 7 to 15 July 1998. Four BSA calculating devices, in current use by the clinical staff, were also tested to determine the formula currently utilized by prescribers.Results. Thirty-three orders sent to the pharmacy containing the patient’s height, weight, and BSA were reviewed. Ninety-four per cent of the BSA calculated by the clinic staff differed from pharmacy’s calculations by 0% to 4%. One BSA calculation differed by 8% and ano...