Programming effectors and coordination in bimanual in-phase mirror finger movements.

We investigated cerebral activation during programming of in-phase symmetric finger movements in a precued response task. Partial precues provided advance information about either mirror effectors or in-phase coordination of bimanual movements, while full precue specified both response parameters and neutral precue no movement information. Effects of precueing were assessed on reaction time (RT), contingent negative variation (CNV), and alpha and beta event-related desynchronization (ERD). Information on coordination mode induced less efficient preparation than information on effectors, as revealed by longer RT, but paradoxically the CNV was found of larger amplitude for in-phase than for mirror precue. Full and in-phase precues were associated to largest cerebral activation, as reflected by CNV amplitude as well as beta ERD. It is suggested that with in-phase precueing, abstract programming of coordination and concrete preparation of possible effectors overlap, engaging more cerebral resources than when symmetric effectors are pre-specified. Alpha ERD underwent regional modulations dependent on the type of preparation, pointing out the role of the right parietal region in visuomotor transformation with full movement programming, and the preferential implication of the dominant hemisphere and medial brain regions in synchronization of both hand movements. Beta ERD topographical distribution suggested an increased implication of bilateral and medial motor regions in anticipation to the response signal with incomplete movement preparation.

[1]  W. Sommer,et al.  Are fingers special? Evidence about movement preparation from event-related brain potentials. , 2003, Psychophysiology.

[2]  L. Leocani,et al.  Event‐Related desynchronization to contingent negative variation and Self‐Paced movement paradigms in Parkinson's disease , 1998, Movement disorders : official journal of the Movement Disorder Society.

[3]  J. Rothwell,et al.  Uncoupling of contingent negative variation and alpha band event-related desynchronization in a go/no-go task , 2001, Clinical Neurophysiology.

[4]  津田 敏雄,et al.  Contingent negative variation , 1984 .

[5]  F. L. D. Silva,et al.  Event-related EEG/MEG synchronization and desynchronization: basic principles , 1999, Clinical Neurophysiology.

[6]  A. E. Schulman,et al.  Functional coupling and regional activation of human cortical motor areas during simple, internally paced and externally paced finger movements. , 1998, Brain : a journal of neurology.

[7]  E.-J. Speckmann,et al.  Introduction of the neurophysiological basis of the EEG and DC potentials , 1993 .

[8]  G. Pfurtscheller.  Central beta rhythm during sensorimotor activities in man. , 1981, Electroencephalography and clinical neurophysiology.

[9]  M. Toyokura,et al.  Relation of bimanual coordination to activation in the sensorimotor cortex and supplementary motor area: Analysis using functional magnetic resonance imaging , 1999, Brain Research Bulletin.

[10]  C. Brunia,et al.  Motor and non-motor aspects of slow brain potentials , 1994, Biological Psychology.

[11]  M. Corbetta,et al.  Control of goal-directed and stimulus-driven attention in the brain , 2002, Nature Reviews Neuroscience.

[12]  Stephen Perrig,et al.  Two Hands—One Action , 1996 .

[13]  Ernst Fernando Lopes Da Silva Niedermeyer,et al.  Electroencephalography, basic principles, clinical applications, and related fields , 1982 .

[14]  E Vaadia,et al.  Who Tells One Hand What the Other Is Doing The Neurophysiology of Bimanual Movements , 1999, Neuron.

[15]  J. Kelso.  Phase transitions and critical behavior in human bimanual coordination. , 1984, The American journal of physiology.

[16]  M. Hallett,et al.  Cerebral structures participating in motor preparation in humans: a positron emission tomography study. , 1996, Journal of neurophysiology.

[17]  J. Kelso,et al.  Governing coordination: behavioural principles and neural correlates , 2003, Experimental Brain Research.

[18]  H. Forssberg,et al.  Neural networks for the coordination of the hands in time. , 2003, Journal of neurophysiology.

[19]  W A MacKay,et al.  CNV, stretch reflex and reaction time correlates of preparation for movement direction and force. , 1990, Electroencephalography and clinical neurophysiology.

[20]  Stephan Bender,et al.  Specific task anticipation versus unspecific orienting reaction during early contingent negative variation , 2004, Clinical Neurophysiology.

[21]  S. Swinnen,et al.  Two hands, one brain: cognitive neuroscience of bimanual skill , 2004, Trends in Cognitive Sciences.

[22]  G. Pfurtscheller,et al.  Event-related cortical desynchronization detected by power measurements of scalp EEG. , 1977, Electroencephalography and clinical neurophysiology.

[23]  D. Rosenbaum.  Human movement initiation: specification of arm, direction, and extent. , 1980, Journal of experimental psychology. General.

[24]  S. H. Curry,et al.  Slow Potential Changes in the Human Brain , 1993, NATO ASI Series.

[25]  K. Stephan,et al.  Cerebral midline structures in bimanual coordination , 1999, Experimental Brain Research.

[26]  Hugo D. Critchley,et al.  Brain activity relating to the contingent negative variation: an fMRI investigation , 2004, NeuroImage.

[27]  A. E. Schulman,et al.  Functional coupling of human cortical sensorimotor areas during bimanual skill acquisition. , 1999, Brain : a journal of neurology.

[28]  末綱 太,et al.  29.脳血管障害者のContingent Negative Variation (CNV) : 特に精神機能障害との関連について(脳卒中 : 高次, 精神機能)(第21回日本リハビリテーション医学会総会) , 1984 .

[29]  J. Foley.  The co-ordination and regulation of movements , 1968 .

[30]  L. Deecke,et al.  High resolution spatiotemporal analysis of the contingent negative variation in simple or complex motor tasks and a non-motor task , 2000, Clinical Neurophysiology.

[31]  Febo Cincotti,et al.  Sub-second "temporal attention" modulates alpha rhythms. A high-resolution EEG study. , 2004, Brain research. Cognitive brain research.

[32]  M Eimer,et al.  Spatial cueing, sensory gating and selective response preparation: an ERP study on visuo-spatial orienting. , 1993, Electroencephalography and clinical neurophysiology.

[33]  V. Ibáñez,et al.  Alpha band power changes in unimanual and bimanual sequential movements, and during motor transitions , 2001, Clinical Neurophysiology.

[34]  Jean Piaget,et al.  Traité de psychologie expérimentale , 1991 .

[35]  I. Jentzsch,et al.  Neural correlates of advance movement preparation: a dipole source analysis approach. , 2001, Brain research. Cognitive brain research.

[36]  Miss A.O. Penney.  (b) , 1974, The New Yale Book of Quotations.

[37]  Rolf Verleger,et al.  Posterior and anterior contribution of hand-movement preparation to late CNV. , 2000 .

[38]  S. Swinnen.  Intermanual coordination: From behavioural principles to neural-network interactions , 2002, Nature Reviews Neuroscience.

[39]  Valentino Bettinardi,et al.  Hemispheric asymmetries and bimanual asynchrony in left- and right-handers , 1998, Experimental Brain Research.

[40]  P. Derambure,et al.  Basic mechanisms of central rhythms reactivity to preparation and execution of a voluntary movement: a stereoelectroencephalographic study , 2003, Clinical Neurophysiology.

[41]  Hartmut Leuthold,et al.  Advance movement preparation of eye, foot, and hand: a comparative study using movement-related brain potentials. , 2002, Brain research. Cognitive brain research.

[42]  Conrad V. Kufta,et al.  Event-related desynchronization and movement-related cortical potentials on the ECoG and EEG. , 1994, Electroencephalography and clinical neurophysiology.

[43]  C. M Gómez,et al.  Preparatory visuo-motor cortical network of the contingent negative variation estimated by current density , 2003, NeuroImage.

[44]  J. Kelso,et al.  Nonequilibrium phase transitions in coordinated biological motion: critical fluctuations , 1986 .

[45]  G. Pfurtscheller,et al.  Patterns of cortical activation during planning of voluntary movement. , 1989, Electroencephalography and clinical neurophysiology.

[46]  M. Hallett,et al.  Event-related coherence and event-related desynchronization/synchronization in the 10 Hz and 20 Hz EEG during self-paced movements. , 1997, Electroencephalography and clinical neurophysiology.

[47]  R. Lesser,et al.  Functional mapping of human sensorimotor cortex with electrocorticographic spectral analysis. I. Alpha and beta event-related desynchronization. , 1998, Brain : a journal of neurology.

[48]  T. Elbert,et al.  Comparison of data transformation procedures to enhance topographical accuracy in time-series analysis of the human EEG , 2002, Journal of Neuroscience Methods.

[49]  L. Goldstein.  The frontal lobes and voluntary action , 1996 .

[50]  T. Sejnowski,et al.  Correlated neuronal activity and the flow of neural information , 2001, Nature Reviews Neuroscience.

[51]  Thomas Elbert,et al.  SLOW CORTICAL POTENTIALS REFLECT THE REGULATION OF CORTICAL EXCITABILITY , 1993 .

[52]  I. Jenkins,et al.  Cerebral control of unimanual and bimanual movements: an H215O PET study , 1998, Neuroreport.

[53]  Christian Gerloff,et al.  Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements , 2003, Clinical Neurophysiology.

[54]  M. Hallett,et al.  The Role of the Medial Wall and Its Anatomical Variations for Bimanual Antiphase and In-Phase Movements , 2001, NeuroImage.

[55]  R. C. Oldfield.  The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[56]  W. Sommer,et al.  Motor programming of response force and movement direction. , 1998, Psychophysiology.

[57]  N. Sadato,et al.  Role of the Supplementary Motor Area and the Right Premotor Cortex in the Coordination of Bimanual Finger Movements , 1997, The Journal of Neuroscience.