Tratamiento de las reacciones cutáneas locales secundarias a ingenol mebutato
暂无分享,去创建一个
J. L. López-Estebaranz | R. Vallejo | M. Fernández-Guarino | M. Sánchez | C. Serra-Guillén | Ignasi Figueras | I. Longo | Juan Luis Artola | E. D. L. Heras | Leandro Martínez | Gemma Oliveras
[1] M. Haedersdal,et al. Topical corticosteroid has no influence on inflammation or efficacy after ingenol mebutate treatment of grade I to III actinic keratoses (AK): A randomized clinical trial. , 2016, Journal of the American Academy of Dermatology.
[2] C. Garbe,et al. Efficacy and safety of follow‐up field treatment of actinic keratosis with ingenol mebutate 0·015% gel: a randomized, controlled 12‐month study , 2016, British Journal of Dermatology.
[3] G. Argenziano,et al. Management of local skin reactions after the application of ingenol mebutate gel for the treatment of actinic keratosis: four illustrative cases , 2016, Journal of the European Academy of Dermatology and Venereology : JEADV.
[4] B. Berman. Safety and tolerability of ingenol mebutate in the treatment of actinic keratosis , 2015, Expert opinion on drug safety.
[5] P. Gerber,et al. Cosmetic Effects of Ingenol Mebutate Gel in the Treatment of Field-Cancerized Photodamaged Skin. , 2015, Dermatologic Surgery.
[6] R. Dellavalle,et al. Long-term Efficacy of Topical Fluorouracil Cream, 5%, for Treating Actinic Keratosis: A Randomized Clinical Trial. , 2015, JAMA dermatology.
[7] A. Ariza,et al. Actinic keratosis with atypical basal cells (AK I) is the most common lesion associated with invasive squamous cell carcinoma of the skin , 2015, Journal of the European Academy of Dermatology and Venereology : JEADV.
[8] M. Augustin,et al. Ingenol mebutate gel for actinic keratosis: the link between quality of life, treatment satisfaction, and clinical outcomes. , 2015, Journal of the American Academy of Dermatology.
[9] M. Lebwohl,et al. A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis , 2015, International journal of dermatology.
[10] Ellen S. Marmur,et al. A New, Objective, Quantitative Scale for Measuring Local Skin Responses Following Topical Actinic Keratosis Therapy with Ingenol Mebutate , 2014, Dermatology and Therapy.
[11] N. Swanson,et al. Efficacy and safety of ingenol mebutate 0.015% gel after cryosurgery of actinic keratosis: 12-month results. , 2014, Journal of drugs in dermatology : JDD.
[12] C. Ferrándiz,et al. Spanish adaptation of the European guidelines for the evaluation and treatment of actinic keratosis. , 2014, Actas dermo-sifiliograficas.
[13] Aditya K. Gupta,et al. Ingenol Mebutate: A Promising Treatment for Actinic Keratoses and Nonmelanoma Skin Cancers , 2013, Journal of cutaneous medicine and surgery.
[14] E. Stockfleth. The paradigm shift in treating actinic keratosis: a comprehensive strategy. , 2012, Journal of drugs in dermatology : JDD.
[15] E. Stockfleth,et al. Diclofenac sodium 3% gel for the management of actinic keratosis: 10+ years of cumulative evidence of efficacy and safety. , 2012, Journal of drugs in dermatology : JDD.
[16] A. Suhrbier,et al. Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches. , 2012, The Journal of investigative dermatology.
[17] Neil Swanson,et al. Ingenol mebutate gel for actinic keratosis. , 2012, The New England journal of medicine.
[18] S. Tyring,et al. Dual mechanism of action of ingenol mebutate gel for topical treatment of actinic keratoses: rapid lesion necrosis followed by lesion-specific immune response. , 2012, Journal of the American Academy of Dermatology.
[19] Ryan W. Hick,et al. From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma. , 2012, The Journal of clinical investigation.
[20] E. Stockfleth,et al. Modes of action of diclofenac 3%/hyaluronic acid 2.5% in the treatment of actinic keratosis , 2011, Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.
[21] M. Ulrich,et al. Emerging drugs for actinic keratosis , 2010, Expert opinion on emerging drugs.
[22] Andrew Lee,et al. The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. , 2010, Cancer research.
[23] J. Lord,et al. Novel Antileukemic Compound Ingenol 3-Angelate Inhibits T Cell Apoptosis by Activating Protein Kinase Cθ* , 2010, The Journal of Biological Chemistry.
[24] J. Lord,et al. Kinetics of ERK1/2 activation determine sensitivity of acute myeloid leukaemia cells to the induction of apoptosis by the novel small molecule ingenol 3-angelate (PEP005) , 2010, Apoptosis.
[25] R. S. Padilla,et al. Gene expression patterns of normal human skin, actinic keratosis, and squamous cell carcinoma: a spectrum of disease progression. , 2010, Archives of dermatology.
[26] Ø. Bruserud,et al. The Protein Kinase C Agonist PEP005 (Ingenol 3-Angelate) in the Treatment of Human Cancer: A Balance between Efficacy and Toxicity , 2010, Toxins.
[27] T. Luger,et al. Predisposing factors of actinic keratosis in a North-West German population. , 2009, European journal of dermatology : EJD.
[28] E. Tschen,et al. Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis. , 2009, Journal of the American Academy of Dermatology.
[29] I. Bièche,et al. Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. , 2009, Cancer research.
[30] S. Ogbourne,et al. PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: Results of a randomized, double‐blind, vehicle‐controlled, multicentre, phase IIa study , 2009, The Australasian journal of dermatology.
[31] E. Raymond,et al. Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells , 2008, British Journal of Cancer.
[32] H. Pehamberger,et al. Development of a treatment algorithm for actinic keratoses: a European Consensus. , 2008, European journal of dermatology : EJD.
[33] J. Lord,et al. Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells , 2008, Molecular Cancer Therapeutics.
[34] D. Kavanagh,et al. Neutrophils Are a Key Component of the Antitumor Efficacy of Topical Chemotherapy with Ingenol-3-Angelate1 , 2006, The Journal of Immunology.
[35] H. Kerl,et al. Guidelines for the management of actinic keratoses. , 2006, European journal of dermatology : EJD.
[36] F. Khanim,et al. PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. , 2005, Blood.
[37] P. Hersey,et al. Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. , 2004, Molecular cancer therapeutics.
[38] D. Murrell,et al. A prospective study of the use of cryosurgery for the treatment of actinic keratoses , 2004, International journal of dermatology.
[39] M. Lebwohl,et al. Imiquimod 5% cream for the treatment of actinic keratosis: results from two phase III, randomized, double-blind, parallel group, vehicle-controlled trials. , 2004, Journal of the American Academy of Dermatology.
[40] P. Parsons,et al. Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. , 2004, Cancer research.
[41] J. Rosso. An update on newer topical therapies for actinic keratoses: advances and applications. , 2003 .
[42] J. Jorizzo,et al. 5-fluorouracil 0.5% cream for multiple actinic or solar keratoses of the face and anterior scalp. , 2001, Skin therapy letter.
[43] M. Johnson,et al. Health effects of sunlight exposure in the United States. Results from the first National Health and Nutrition Examination Survey, 1971-1974. , 1988, Archives of dermatology.