Heme oxygenase-1 regulates autophagy through carbon–oxygen to alleviate deoxynivalenol-induced hepatic damage

[1]  Liegang Liu,et al.  Heme oxygenase-1 attenuates low-dose of deoxynivalenol-induced liver inflammation potentially associating with microbiota. , 2019, Toxicology and applied pharmacology.

[2]  S. Ryter,et al.  Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury , 2018, Cell Death & Disease.

[3]  Jikai Wen,et al.  JNK‐AKT‐NF‐&kgr;B controls P‐glycoprotein expression to attenuate the cytotoxicity of deoxynivalenol in mammalian cells , 2018, Biochemical pharmacology.

[4]  M. Mulero,et al.  Resveratrol Potently Counteracts Quercetin Starvation‐Induced Autophagy and Sensitizes HepG2 Cancer Cells to Apoptosis , 2018, Molecular nutrition & food research.

[5]  Ying Sun,et al.  Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[6]  M. Komatsu,et al.  Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways , 2017, Redox biology.

[7]  S. Ryter,et al.  Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin‐2 via the PERK‐eIF2&agr;‐ATF4 pathway , 2017, Free radical biology & medicine.

[8]  Hailong Wu,et al.  The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy , 2017, Cell Death & Disease.

[9]  S. Kersten,et al.  Chronic DON exposure and acute LPS challenge: effects on porcine liver morphology and function , 2017, Mycotoxin Research.

[10]  L. Carneiro,et al.  Heme and iron induce protein aggregation , 2017, Autophagy.

[11]  Y. Wang,et al.  In vivo toxicity assessment of deoxynivalenol-contaminated wheat after ozone degradation , 2017, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[12]  L. Carneiro,et al.  Protein aggregation as a cellular response to oxidative stress induced by heme and iron , 2016, Proceedings of the National Academy of Sciences.

[13]  X. Cui,et al.  Deoxynivalenol exposure induces autophagy/apoptosis and epigenetic modification changes during porcine oocyte maturation. , 2016, Toxicology and applied pharmacology.

[14]  Fengna Li,et al.  Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway. , 2015, Free radical biology & medicine.

[15]  R. Barbouche,et al.  The food born mycotoxin deoxynivalenol induces low-grade inflammation in mice in the absence of observed-adverse effects. , 2015, Toxicology letters.

[16]  P. Dennery.  Signaling function of heme oxygenase proteins. , 2014, Antioxidants & redox signaling.

[17]  Sun-Mee Lee,et al.  Impaired autophagy contributes to hepatocellular damage during ischemia/reperfusion: heme oxygenase-1 as a possible regulator. , 2014, Free radical biology & medicine.

[18]  J. Groopman,et al.  Public health impacts of foodborne mycotoxins. , 2014, Annual review of food science and technology.

[19]  W. Bao,et al.  Deoxynivalenol induced oxidative stress and genotoxicity in human peripheral blood lymphocytes. , 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[20]  S. Ryter,et al.  Carbon monoxide confers protection in sepsis by enhancing beclin 1-dependent autophagy and phagocytosis. , 2014, Antioxidants & redox signaling.

[21]  M. Das,et al.  Influence of temperature and pH on the degradation of deoxynivalenol (DON) in aqueous medium: comparative cytotoxicity of DON and degraded product , 2014, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[22]  M. Maresca.  From the Gut to the Brain: Journey and Pathophysiological Effects of the Food-Associated Trichothecene Mycotoxin Deoxynivalenol , 2013, Toxins.

[23]  C. Lemaire,et al.  Involvement of mitochondria-mediated apoptosis in deoxynivalenol cytotoxicity. , 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[24]  H. Humpf,et al.  Impact of physicochemical parameters on the decomposition of deoxynivalenol during extrusion cooking of wheat grits. , 2011, Journal of agricultural and food chemistry.

[25]  A. Jean,et al.  Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: a PGE2-independent mechanism. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[26]  S. Ryter,et al.  Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation. , 2011, American journal of respiratory cell and molecular biology.

[27]  M. Rosengart,et al.  Heme oxygenase‐1–mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice , 2011, Hepatology.

[28]  Yongqiang Chen,et al.  The regulation of autophagy – unanswered questions , 2011, Journal of Cell Science.

[29]  J. Pestka.  Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance , 2010, Archives of Toxicology.

[30]  D. Klionsky,et al.  Regulation mechanisms and signaling pathways of autophagy. , 2009, Annual review of genetics.

[31]  Yoshiaki Kamada,et al.  Dynamics and diversity in autophagy mechanisms: lessons from yeast , 2009, Nature Reviews Molecular Cell Biology.

[32]  J. Pestka,et al.  Tissue distribution and proinflammatory cytokine induction by the trichothecene deoxynivalenol in the mouse: comparison of nasal vs. oral exposure. , 2008, Toxicology.

[33]  Daniel J. Klionsky,et al.  Autophagy fights disease through cellular self-digestion , 2008, Nature.

[34]  A. Nussler,et al.  Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. , 2007, Journal of hepatology.

[35]  T. Loop,et al.  Heme Oxygenase-1 Induction by the Clinically Used Anesthetic Isoflurane Protects Rat Livers From Ischemia/Reperfusion Injury , 2007, Annals of surgery.

[36]  N. Skovgaard.  Safety evaluation of certain contaminants in food , 2007 .

[37]  G. Klintmalm,et al.  Radio‐frequency ablation of hepatocellular carcinoma before liver transplantation: a histologic and ‘TUNEL’ study , 2006, Liver international : official journal of the International Association for the Study of the Liver.

[38]  Z. Islam,et al.  Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.

[39]  R. Alberto,et al.  CORM‐A1: a new pharmacologically active carbon monoxide‐releasing molecule , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[40]  J. Pestka,et al.  Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. , 2004, Toxicology letters.

[41]  S. Sassa,et al.  Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries. , 2004, Current medicinal chemistry.

[42]  H. Volk,et al.  Heme oxygenase‐1 and its reaction product, carbon monoxide, prevent inflammation‐related apoptotic liver damage in mice , 2003, Hepatology.

[43]  H. Volk,et al.  Original Articles: Liver Biology and PathobiologyHeme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice☆ , 2003 .

[44]  M. Maines.  Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications , 1988, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[45]  E. Marra,et al.  Kinetic studies of the uptake of aspartate aminotransferase and malate dehydrogenase into mitochondria in vitro. , 1985, The Biochemical journal.

[46]  H. Marver,et al.  The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[47]  L. Tang,et al.  Deoxynivalenol decreased intestinal immune function related to NF-κB and TOR signalling in juvenile grass carp (Ctenopharyngodon idella). , 2019, Fish & shellfish immunology.