Inhibition of HER1 signaling pathway enhances antitumor effect of endocrine therapy in breast cancer
暂无分享,去创建一个
[1] K. Tanaka,et al. Additive antitumour effect of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa, ZD1839) and the antioestrogen fulvestrant (Faslodex, ICI 182,780) in breast cancer cells , 2004, British Journal of Cancer.
[2] C. Arteaga,et al. The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors. , 2003, Seminars in oncology.
[3] M. Ebina,et al. Severe acute interstitial pneumonia and gefitinib , 2003, The Lancet.
[4] A. Harris,et al. Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] C. Morris. The Role of EGFR-Directed Therapy in the Treatment of Breast Cancer , 2002, Breast Cancer Research and Treatment.
[6] C. Arteaga. Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia. , 2002, Seminars in oncology.
[7] Roy S Herbst,et al. Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] C. Arteaga. Epidermal growth factor receptor dependence in human tumors: more than just expression? , 2002, The oncologist.
[9] M. Kris,et al. ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] R. Bianco,et al. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. , 2001, Cancer research.
[11] H. Kurokawa,et al. Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[12] Simak Ali,et al. Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α , 2001, The Journal of Biological Chemistry.
[13] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[14] B. Katzenellenbogen,et al. A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. , 2000, Endocrinology.
[15] Simak Ali,et al. Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7. , 2000, Molecular cell.
[16] D. Picard,et al. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. , 1996, The EMBO journal.
[17] Daniel Metzger,et al. Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase , 1995, Science.
[18] J. Foekens,et al. Ectopic expression of epidermal growth factor receptors induces hormone independence in ZR-75-1 human breast cancer cells. , 1992, Cancer research.
[19] J. Farndon,et al. EXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTORS ASSOCIATED WITH LACK OF RESPONSE TO ENDOCRINE THERAPY IN RECURRENT BREAST CANCER , 1989, The Lancet.
[20] F. Taggi. SAFETY HELMET LAW IN ITALY , 1988, The Lancet.
[21] L. Jackson. Chromosomes and cancer: current aspects. , 1978, Seminars in oncology.
[22] J. Kurebayashi,et al. Endocrine-resistant breast cancer: Underlying mechanisms and strategies for overcoming resistance , 2003, Breast cancer.
[23] M. Dowsett,et al. Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[24] Yutaka Yamamoto. Prognostic and Predictive Values of HER1 and HER2 Overexpression in Breast Cancer , 2003 .
[25] J. Kurebayashi. Biological and clinical significance of her2 overexpression in Breast Cancer , 2001, Breast cancer.