Structure and function of Toll receptors and their ligands.
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[1] A. Kajava. Structural diversity of leucine-rich repeat proteins. , 1998, Journal of molecular biology.
[2] S. Akira,et al. Recognition of pathogen-associated molecular patterns by TLR family. , 2003, Immunology letters.
[3] S. Fesik,et al. Insights into Programmed Cell Death through Structural Biology , 2000, Cell.
[4] N. Gay,et al. Sensing of Gram‐positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP‐SA , 2006, The EMBO journal.
[5] S. Nair,et al. Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling1 , 2005, The Journal of Immunology.
[6] N. Gay,et al. Conserved Features in the Extracellular Domain of Human Toll-like Receptor 8 Are Essential for pH-dependent Signaling* , 2006, Journal of Biological Chemistry.
[7] S. Akira,et al. Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins1 , 2002, The Journal of Immunology.
[8] C. Janeway,et al. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity , 1997, Nature.
[9] N. Gay,et al. Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[10] Zhonghe Zhou,et al. The smallest known non-avian theropod dinosaur , 2000, Nature.
[11] G. Hardiman,et al. A family of human receptors structurally related to Drosophila Toll. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[12] F. Re,et al. Monomeric Recombinant MD-2 Binds Toll-like Receptor 4 Tightly and Confers Lipopolysaccharide Responsiveness* , 2002, The Journal of Biological Chemistry.
[13] C. Jefferies,et al. MyD88 Adapter-like (Mal) Is Phosphorylated by Bruton's Tyrosine Kinase during TLR2 and TLR4 Signal Transduction* , 2006, Journal of Biological Chemistry.
[14] Makiko Kobayashi,et al. Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization. , 2004, International immunology.
[15] N. Gay,et al. Ligand-Receptor and Receptor-Receptor Interactions Act in Concert to Activate Signaling in the Drosophila Toll Pathway*♦ , 2005, Journal of Biological Chemistry.
[16] W. Hancock,et al. Fibrinogen Stimulates Macrophage Chemokine Secretion Through Toll-Like Receptor 41 , 2001, The Journal of Immunology.
[17] N. Gay,et al. Drosophila Toll and IL-1 receptor , 1991, Nature.
[18] J. Deisenhofer,et al. The leucine-rich repeat: a versatile binding motif. , 1994, Trends in biochemical sciences.
[19] H. Kolb,et al. Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex1 , 2000, The Journal of Immunology.
[20] M. Neuberger,et al. Molecular mechanisms of antibody somatic hypermutation. , 2007, Annual review of biochemistry.
[21] Jongdae Lee,et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[22] T. Maniatis,et al. The Role of Ubiquitination in Drosophila Innate Immunity* , 2005, Journal of Biological Chemistry.
[23] P. Godowski,et al. The apoptotic signaling pathway activated by Toll‐like receptor‐2 , 2000, The EMBO journal.
[24] B. Lemaître,et al. The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults , 1996, Cell.
[25] B. Lemaître,et al. A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. , 2006, Developmental cell.
[26] S. Akira,et al. Discrimination of bacterial lipoproteins by Toll-like receptor 6. , 2001, International immunology.
[27] I. Wilson,et al. Crystal Structure of Human Toll-Like Receptor 3 (TLR3) Ectodomain , 2005, Science.
[28] Douglas T. Golenbock,et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus , 2000, Nature Immunology.
[29] F. Liew,et al. Negative regulation of Toll-like receptor-mediated immune responses , 2005, Nature Reviews Immunology.
[30] Y. Kawai,et al. Toll-Like Receptor 4-MD-2 Complex Mediates the Signal Transduction Induced by Flavolipin, an Amino Acid-Containing Lipid Unique to Flavobacterium meningosepticum1 , 2002, The Journal of Immunology.
[31] L. Anderson,et al. Involvement of Toll-Like Receptor 4 in Innate Immunity to Respiratory Syncytial Virus , 2001, Journal of Virology.
[32] S. Sprang,et al. Three-Dimensional Structure of a Complex between the Death Domains of Pelle and Tube , 1999, Cell.
[33] N. Gay,et al. Solution structure of the isolated Pelle death domain , 2005, FEBS letters.
[34] V. ter meulen,et al. Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling , 2002, Journal of Virology.
[35] L. O’Neill,et al. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. , 2004, Molecular immunology.
[36] M. Shlomchik,et al. Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors , 2002, Nature.
[37] S. Ross,et al. Murine retroviruses activate B cells via interaction with toll-like receptor 4 , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[38] Ashish,et al. Structural and Functional Evidence for the Role of the TLR2 DD Loop in TLR1/TLR2 Heterodimerization and Signaling* , 2006, Journal of Biological Chemistry.
[39] H. Karahashi,et al. Chlamydial Heat Shock Protein 60 Activates Macrophages and Endothelial Cells Through Toll-Like Receptor 4 and MD2 in a MyD88-Dependent Pathway1 , 2002, The Journal of Immunology.
[40] J. Hoffmann,et al. Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease , 2002, Science.
[41] A. Aderem,et al. Cutting Edge: Functional Interactions Between Toll-Like Receptor (TLR) 2 and TLR1 or TLR6 in Response to Phenol-Soluble Modulin1 , 2001, The Journal of Immunology.
[42] P. Cao,et al. Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling* , 2004, Journal of Biological Chemistry.
[43] D. Davies,et al. The molecular structure of the Toll-like receptor 3 ligand-binding domain. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[44] M. Mann,et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 , 2006, Nature.
[45] D. Kuhns,et al. Cutting Edge: Expression of IL-1 Receptor-Associated Kinase-4 (IRAK-4) Proteins with Mutations Identified in a Patient with Recurrent Bacterial Infections Alters Normal IRAK-4 Interaction with Components of the IL-1 Receptor Complex1 , 2005, The Journal of Immunology.
[46] S. Mizel,et al. Identification of a Sequence in Human Toll-like Receptor 5 Required for the Binding of Gram-negative Flagellin* , 2003, Journal of Biological Chemistry.
[47] F. Sutterwala,et al. Reversal of Proinflammatory Responses by Ligating the Macrophage Fcγ Receptor Type I , 1998, The Journal of experimental medicine.
[48] N. Gay,et al. Role of the Spätzle Pro-domain in the Generation of an Active Toll Receptor Ligand* , 2007, Journal of Biological Chemistry.
[49] S. Akira,et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 , 2001, Nature.
[50] Daniel R. Caffrey,et al. LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF , 2003, The Journal of experimental medicine.
[51] R. Flavell,et al. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 , 2001, Nature.
[52] S. Wasserman,et al. Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo. , 1998, Development.
[53] J. Platt,et al. Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 41 , 2002, The Journal of Immunology.
[54] E. Koonin,et al. The domains of death: evolution of the apoptosis machinery. , 1999, Trends in biochemical sciences.
[55] S. Akira,et al. Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite1 , 2001, The Journal of Immunology.
[56] J. Manley,et al. Pelle kinase is activated by autophosphorylation during Toll signaling in Drosophila. , 2002, Development.
[57] J. Hoffmann,et al. The immune response of Drosophila , 2003, Nature.
[58] T. Ahrens,et al. Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4 , 2002, The Journal of experimental medicine.
[59] Osamu Takeuchi,et al. The Roles of Two IκB Kinase-related Kinases in Lipopolysaccharide and Double Stranded RNA Signaling and Viral Infection , 2004, The Journal of experimental medicine.
[60] Christian Wiesmann,et al. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor , 1999, Nature.
[61] R. Medzhitov,et al. Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling , 2006, Cell.
[62] M. J. Cody,et al. Signaling by Toll-Like Receptor 2 and 4 Agonists Results in Differential Gene Expression in Murine Macrophages , 2001, Infection and Immunity.
[63] T. Yoshida,et al. Mouse Toll-like Receptor 4·MD-2 Complex Mediates Lipopolysaccharide-mimetic Signal Transduction by Taxol* , 2000, The Journal of Biological Chemistry.
[64] M. Fenton,et al. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. , 2003, Molecular interventions.
[65] J. Gordon,et al. Genetic and biochemical studies of protein N-myristoylation. , 1994, Annual review of biochemistry.
[66] Jerome F. Strauss,et al. The Extra Domain A of Fibronectin Activates Toll-like Receptor 4* , 2001, The Journal of Biological Chemistry.
[67] S. Akira,et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway , 2002, Nature Immunology.
[68] S. Akira,et al. The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[69] A. Aderem,et al. Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism , 2001, Nature Immunology.
[70] S. Akira,et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[71] U. Göbel,et al. Toll-like Receptor-2 Mediates Treponema Glycolipid and Lipoteichoic Acid-induced NF-κB Translocation* , 2001, The Journal of Biological Chemistry.
[72] D. Golenbock,et al. Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent1 , 2002, The Journal of Immunology.
[73] Holger Wesche,et al. IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[74] B. Monks,et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome , 2004, Nature Immunology.
[75] K. Anderson,et al. Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNA , 1984, Nature.
[76] R. Zhou,et al. Role of Drosophila IKKγ in a Toll-independent antibacterial immune response , 2000, Nature Immunology.
[77] R. Tapping,et al. Domain Exchange between Human Toll-like Receptors 1 and 6 Reveals a Region Required for Lipopeptide Discrimination* , 2005, Journal of Biological Chemistry.
[78] S. Tauszig-Delamasure,et al. Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections , 2002, Nature Immunology.
[79] H. Wagner,et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 , 2002, Nature Immunology.
[80] J. Bazan,et al. Pathogen recognition: TLRs throw us a curve. , 2005, Immunity.
[81] B. Bloom,et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. , 1999, Science.
[82] D. Mosser,et al. A novel phenotype for an activated macrophage: the type 2 activated macrophage , 2002, Journal of leukocyte biology.
[83] D. Davies,et al. The dsRNA binding site of human Toll‐like receptor 3 , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[84] S. Akira,et al. TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway , 2003, Nature Immunology.
[85] K. Miyake,et al. Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. , 2002, Biochemical and biophysical research communications.
[86] G. Núñez,et al. ML -- a conserved domain involved in innate immunity and lipid metabolism. , 2002, Trends in biochemical sciences.
[87] Zhijian J. Chen,et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK , 2001, Nature.
[88] Shizuo Akira,et al. Toll-like receptor signalling , 2004, Nature Reviews Immunology.
[89] Thomas Hartung,et al. CD36 is a sensor of diacylglycerides , 2005, Nature.
[90] M. Offermann,et al. Apoptosis Induced by the Toll-Like Receptor Adaptor TRIF Is Dependent on Its Receptor Interacting Protein Homotypic Interaction Motif1 , 2005, The Journal of Immunology.
[91] N. Glaichenhaus,et al. TLR4 and Toll-IL-1 Receptor Domain-Containing Adapter-Inducing IFN-β, but Not MyD88, Regulate Escherichia coli-Induced Dendritic Cell Maturation and Apoptosis In Vivo1 , 2005, The Journal of Immunology.
[92] Y. Barde,et al. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. , 2000, Genes & development.
[93] C. Schutt,et al. Three-dimensional structure of CheY, the response regulator of bacterial chemotaxis , 1989, Nature.
[94] Michael Rehli,et al. Novel Signal Transduction Pathway Utilized by Extracellular HSP70 , 2002, The Journal of Biological Chemistry.
[95] N. Gay,et al. Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor. , 1999, Biochemistry.
[96] K. Basler,et al. A Genetic Screen Targeting the Tumor Necrosis Factor/Eiger Signaling Pathway: Identification of Drosophila TAB2 as a Functionally Conserved Component , 2005, Genetics.
[97] T. Maniatis,et al. IKKε and TBK1 are essential components of the IRF3 signaling pathway , 2003, Nature Immunology.
[98] M. Horton,et al. Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR21 , 2006, The Journal of Immunology.
[99] K. Garcia,et al. Structure of Nerve Growth Factor Complexed with the Shared Neurotrophin Receptor p75 , 2004, Science.
[100] E. Fikrig,et al. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice , 2002, Nature Medicine.
[101] Galina V. Glazko,et al. Diversity and Function of Adaptive Immune Receptors in a Jawless Vertebrate , 2005, Science.
[102] K. Anderson,et al. A conserved signaling pathway: the Drosophila toll-dorsal pathway. , 1996, Annual review of cell and developmental biology.
[103] M. Rothe,et al. Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2* , 1999, The Journal of Biological Chemistry.
[104] J. Banchereau,et al. Pyogenic Bacterial Infections in Humans with MyD88 Deficiency , 2003, Science.
[105] D. Golenbock,et al. Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. , 1991, The Journal of biological chemistry.
[106] P. Ricciardi-Castagnoli,et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. , 1998, Science.
[107] D. Pennington,et al. Protein Kinase C (cid:2) Is Required for Macrophage Activation and Defense Against Bacterial Infection , 2001 .
[108] Y. Ip,et al. Multimerization and interaction of Toll and Spätzle in Drosophila. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[109] B. Beutler,et al. LPS, dsRNA and the interferon bridge to adaptive immune responses: Trif, Tram, and other TIR adaptor proteins. , 2004, Journal of endotoxin research.
[110] D. Schwartz,et al. Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling , 2001 .
[111] Ki-Young Lee,et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. , 2005, Genes & development.
[112] C. Coban,et al. Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 , 2004, Nature Immunology.
[113] N. Gay,et al. MD-2: the Toll 'gatekeeper' in endotoxin signalling. , 2004, Trends in biochemical sciences.
[114] S. Akira,et al. Toll‐like receptor 6‐independent signaling by diacylated lipopeptides , 2005, European journal of immunology.
[115] K. Mizuguchi,et al. Getting knotted: a model for the structure and activation of Spätzle. , 1998, Trends in biochemical sciences.
[116] H. Wong,et al. Salmonella Flagellin-Dependent Proinflammatory Responses Are Localized to the Conserved Amino and Carboxyl Regions of the Protein1 , 2001, The Journal of Immunology.
[117] K. Anderson,et al. Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo. , 1991, Genes & development.
[118] R. Ulevitch,et al. MD-2 and TLR4 N-Linked Glycosylations Are Important for a Functional Lipopolysaccharide Receptor* , 2002, The Journal of Biological Chemistry.
[119] L. Joosten,et al. Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis1 , 2006, The Journal of Immunology.
[120] N. Gay,et al. Structural Complementarity of Toll/Interleukin-1 Receptor Domains in Toll-like Receptors and the Adaptors Mal and MyD88* , 2003, Journal of Biological Chemistry.
[121] D. Underhill,et al. Dectin‐1 mediates macrophage recognition of Candida albicans yeast but not filaments , 2005, The EMBO journal.
[122] N. Gay,et al. Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling , 2003, Nature Immunology.
[123] A. Robidoux,et al. E5531, a pure endotoxin antagonist of high potency. , 1995, Science.
[124] A. Aderem,et al. The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions. , 1995, Trends in biochemical sciences.
[125] J. Manley,et al. Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[126] I. Wilson,et al. Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[127] S. Akira,et al. Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8 , 2004, Science.
[128] D. Rossignol,et al. Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia. , 2003, The Journal of infectious diseases.
[129] A. Aderem,et al. Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility , 2003, Nature Immunology.
[130] M. Boukhvalova,et al. Analysis of TLR4 Polymorphic Variants: New Insights into TLR4/MD-2/CD14 Stoichiometry, Structure, and Signaling1 , 2006, The Journal of Immunology.
[131] B. Monks,et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. , 2000, The Journal of clinical investigation.
[132] Zhijian J. Chen,et al. Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.
[133] J. V. Ravetch,et al. IgG Fc receptors. , 2001, Annual review of immunology.
[134] W. Xiao,et al. The TRAF6 RING finger domain mediates physical interaction with Ubc13 , 2004, FEBS letters.
[135] A. Shahangian,et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response , 2006, Nature.
[136] P. Tobias,et al. MD-2 binds to bacterial lipopolysaccharide. , 2001, Journal of endotoxin research.
[137] N. Gay,et al. Toll-like receptors as molecular switches , 2006, Nature Reviews Immunology.
[138] Paul J Hertzog,et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation , 2006, Nature Immunology.
[139] Seng-Lai Tan,et al. Emerging and diverse roles of protein kinase C in immune cell signalling. , 2003, The Biochemical journal.
[140] Zhijian J. Chen,et al. TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. , 2004, Molecular cell.
[141] W. Yeh,et al. IRAK-4 as the central TIR signaling mediator in innate immunity. , 2002, Trends in immunology.
[142] K. Anderson,et al. Establishment of dorsal-ventral polarity in the drosophila embryo: The induction of polarity by the Toll gene product , 1985, Cell.
[143] Sophie Janssens,et al. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members. , 2003, Molecular cell.
[144] N. Gay,et al. Structural and functional diversity in the leucine-rich repeat family of proteins. , 1996, Progress in biophysics and molecular biology.
[145] S. Wasserman,et al. Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning , 2004, The EMBO journal.
[146] P. Godowski,et al. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. , 1999, Science.
[147] S. Akira,et al. Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway , 2003, Science.
[148] E. Kiss-Toth,et al. Evidence for an Accessory Protein Function for Toll-Like Receptor 1 in Anti-Bacterial Responses1 , 2000, The Journal of Immunology.
[149] K. Anderson,et al. The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein , 1988, Cell.
[150] Shizuo Akira,et al. Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA , 2004, Science.
[151] H. Heine,et al. Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1 , 2005, European journal of immunology.
[152] K. Mizuguchi,et al. A family of proteins related to Spätzle, the toll receptor ligand, are encoded in the Drosophila genome , 2001, Proteins.
[153] F. Inagaki,et al. Identification of Ser-386 of Interferon Regulatory Factor 3 as Critical Target for Inducible Phosphorylation That Determines Activation* , 2004, Journal of Biological Chemistry.
[154] J. Casanova,et al. IRAK4 Kinase Activity Is Redundant for Interleukin-1 (IL-1) Receptor-associated Kinase Phosphorylation and IL-1 Responsiveness* , 2004, Journal of Biological Chemistry.
[155] A. Aderem,et al. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[156] C. Janeway. Approaching the asymptote? Evolution and revolution in immunology. , 1989, Cold Spring Harbor symposia on quantitative biology.
[157] T. Taniguchi,et al. Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction , 2000 .
[158] T. Steitz,et al. Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution. , 1999, Biochemistry.