Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.
暂无分享,去创建一个
Weiliang Zhu | Jian Li | Ky-Youb Nam | Kyoung Tai No | Ning Li | Jian-Ping Zuo | Hualiang Jiang | Ning Li | Hong Liu | Jian Li | K. No | Ky-Youb Nam | Jian-Ping Zuo | E. Feng | B. Seong | Woo-Jin Shin | Wei Tang | Hong Liu | Pei-Lan He | Hualiang Jiang | Enguang Feng | Wei Zhu | Woo-Jin Shin | Wei Tang | Deju Ye | Deju Ye | Hanjo Kim | Baik-Lin Seong | Pei-lan He | Hanjo Kim
[1] Jim Euchner. Design , 2014, Catalysis from A to Z.
[2] Fanbo Jing,et al. Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors. , 2011, Bioorganic & Medicinal Chemistry.
[3] P. Kerry,et al. Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase , 2010, Nature communications.
[4] Thomas S. Peat,et al. Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses† , 2010, Journal of medicinal chemistry.
[5] Jianzhu Chen,et al. Attaching zanamivir to a polymer markedly enhances its activity against drug-resistant strains of influenza a virus. , 2010, Journal of pharmaceutical sciences.
[6] A. Yang,et al. Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. , 2010, Bioorganic & medicinal chemistry.
[7] B. Seong,et al. Reverse genetic platform for inactivated and live-attenuated influenza vaccine , 2010, Experimental & Molecular Medicine.
[8] B. Seong,et al. Broad‐spectrum antiviral effect of Agrimonia pilosa extract on influenza viruses , 2010, Microbiology and immunology.
[9] J. Magano. Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza. , 2009, Chemical reviews.
[10] Chi‐Huey Wong,et al. Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus. , 2009, Journal of medicinal chemistry.
[11] M. Yamashita,et al. Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en. , 2009, Bioorganic & medicinal chemistry letters.
[12] Steven J. M. Jones,et al. A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase. , 2009, Journal of medicinal chemistry.
[13] F. Totzke,et al. N-substituted 2'-(aminoaryl)benzothiazoles as kinase inhibitors: hit identification and scaffold hopping. , 2009, Bioorganic & medicinal chemistry letters.
[14] Hualiang Jiang,et al. Efficient dehydrative sialylation of C-4-aminated sialyl-hemiketal donors with Ph2SO/Tf2O. , 2009, The Journal of organic chemistry.
[15] Hualiang Jiang,et al. Simultaneous 2-O-deacetylation and 4-amination of peracetylated Neu5Ac: application to the synthesis of (4 -> 4)-piperazine derivatives linked sialic acid dimers , 2008 .
[16] Alan J. Hay,et al. Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants , 2008, Nature.
[17] Hualiang Jiang,et al. Simultaneous Stereoselective 4-Amination with Cyclic Secondary Amines and 2-O-Deacetylation of Peracetylated Sialic Acid Derivatives. , 2007 .
[18] Zhuo-rong Li,et al. Synthesis and anti-influenza activities of carboxyl alkoxyalkyl esters of 4-guanidino-Neu5Ac2en (zanamivir). , 2007, Bioorganic & medicinal chemistry letters.
[19] Hualiang Jiang,et al. Simultaneous stereoselective 4-amination with cyclic secondary amines and 2-O-deacetylation of peracetylated sialic acid derivatives , 2007 .
[20] E. De Clercq,et al. Anti‐influenza virus agents: Synthesis and mode of action , 2006, Medicinal research reviews.
[21] Weiliang Zhu,et al. Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities. , 2006, Bioorganic & medicinal chemistry letters.
[22] David J. Stevens,et al. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design , 2006, Nature.
[23] Jie Zhang,et al. Recent advances in anti-influenza agents with neuraminidase as target. , 2006, Mini reviews in medicinal chemistry.
[24] Alexey Bochkarev,et al. An epidemiologically significant epitope of a 1998 human influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex. , 2005, Journal of molecular biology.
[25] Stephanie Hamilton,et al. Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza. , 2005, Journal of medicinal chemistry.
[26] Tianbao Lu. Oxyguanidines. Part 2. Discovery of a Novel Orally Active Thrombin Inhibitor Through Structure-Based Drug Design and Parallel Synthesis. , 2004 .
[27] R. Webster,et al. Comparison of Efficacies of RWJ-270201, Zanamivir, and Oseltamivir against H5N1, H9N2, and Other Avian Influenza Viruses , 2001, Antimicrobial Agents and Chemotherapy.
[28] Mark von Itzstein,et al. The war against influenza: discovery and development of sialidase inhibitors. , 2007, Nature reviews. Drug discovery.
[29] Jonathan Greer,et al. Influenza neuraminidase inhibitors: structure-based design of a novel inhibitor series. , 2003, Biochemistry.
[30] P. Wyatt,et al. Approaches to carbocyclic analogues of the potent neuraminidase inhibitor 4-guanidino-Neu5Ac2en. X-Ray molecular structure of N-[(1S,2S,6R)-2-azido-6-benzyloxymethyl-4-formylcyclohex-3-enyl]acetamide , 1995 .