Endogenous myoglobin expression in mouse models of mammary carcinoma reduces hypoxia and metastasis in PyMT mice

[1]  Jonathan L. Schmid-Burgk,et al.  Myoglobin regulates fatty acid trafficking and lipid metabolism in mammary epithelial cells , 2022, PloS one.

[2]  M. Gassmann,et al.  Pro-Apoptotic and Anti-Invasive Properties Underscore the Tumor-Suppressing Impact of Myoglobin on a Subset of Human Breast Cancer Cells , 2022, bioRxiv.

[3]  M. Gassmann,et al.  Myoglobin, expressed in brown adipose tissue of mice, regulates the content and activity of mitochondria and lipid droplets. , 2021, Biochimica et biophysica acta. Molecular and cell biology of lipids.

[4]  W. Muller,et al.  Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo , 2020, Oncogene.

[5]  Minying Zheng,et al.  Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor , 2020, Stem cells international.

[6]  G. Kristiansen,et al.  The role of myoglobin in epithelial cancers: Insights from transcriptomics , 2019, International journal of molecular medicine.

[7]  H. Becker.  Carbonic anhydrase IX and acid transport in cancer , 2019, British Journal of Cancer.

[8]  J. Condeelis,et al.  The Different Routes to Metastasis via Hypoxia-Regulated Programs. , 2018, Trends in cell biology.

[9]  T. Jue,et al.  Differential Interaction of Myoglobin with Select Fatty Acids of Carbon Chain Lengths C8 to C16 , 2017, Lipids.

[10]  G. Kristiansen,et al.  Ectopic Myoglobin Expression Is Associated with a Favourable Outcome in Head and Neck Squamous Cell Carcinoma Patients. , 2016, Anticancer research.

[11]  S. Adams,et al.  Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin* , 2016, The Journal of Biological Chemistry.

[12]  Abdel Kareem Azab,et al.  The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy , 2015, Hypoxia.

[13]  G. Kristiansen,et al.  Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia , 2014, Virchows Archiv.

[14]  R. Cardiff,et al.  Proliferative and Nonproliferative Lesions of the Rat and Mouse Mammary, Zymbal’s, Preputial, and Clitoral Glands , 2012, Toxicologic pathology.

[15]  T. Liloglou,et al.  Neuroglobin and myoglobin in non-small cell lung cancer: expression, regulation and prognosis. , 2011, Lung cancer.

[16]  Holger Moch,et al.  Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity , 2011, The Journal of Biological Chemistry.

[17]  S. Agelaki,et al.  Epithelial to mesenchymal transition markers expressed in circulating tumour cells of early and metastatic breast cancer patients , 2011, Breast Cancer Research.

[18]  M Dietel,et al.  Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype , 2010, British Journal of Cancer.

[19]  B. Schaffhausen,et al.  Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen , 2009, Microbiology and Molecular Biology Reviews.

[20]  A. Bardelli,et al.  Expression and functional regulation of myoglobin in epithelial cancers. , 2009, The American journal of pathology.

[21]  P. Lambin,et al.  Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response* , 2009, The Journal of Biological Chemistry.

[22]  U. Kreutzer,et al.  Interaction of fatty acid with myoglobin , 2008, FEBS letters.

[23]  R. Dummer,et al.  In vivo switching of human melanoma cells between proliferative and invasive states. , 2008, Cancer research.

[24]  G. Minotti,et al.  Doxorubicin Degradation in Cardiomyocytes , 2007, Journal of Pharmacology and Experimental Therapeutics.

[25]  Misa Nakamura,et al.  Nitric oxide in breast cancer: induction of vascular endothelial growth factor-C and correlation with metastasis and poor prognosis. , 2006, Clinical cancer research : an official journal of the American Association for Cancer Research.

[26]  A. Urbani,et al.  Oxidative Degradation of Cardiotoxic Anticancer Anthracyclines to Phthalic Acids , 2004, Journal of Biological Chemistry.

[27]  Jeffrey W Pollard,et al.  Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. , 2003, The American journal of pathology.

[28]  B. Wittenberg,et al.  Myoglobin function reassessed , 2003, Journal of Experimental Biology.

[29]  A. Berns,et al.  Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer , 2001, Nature Genetics.

[30]  U. Flögel,et al.  Disruption of myoglobin in mice induces multiple compensatory mechanisms. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[31]  G. Klein,et al.  Role of p53 mutation in polyomavirus-induced tumorigenesis. , 1997, The Journal of general virology.

[32]  K. Groebe,et al.  Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids , 1995, International journal of cancer.

[33]  R. Cardiff,et al.  Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease , 1992, Molecular and cellular biology.

[34]  T. Jue,et al.  Palmitate interaction with physiological states of myoglobin. , 2014, Biochimica et biophysica acta.

[35]  T. Seyfried,et al.  On the origin of cancer metastasis. , 2013, Critical reviews in oncogenesis.

[36]  W. Stetler-Stevenson,et al.  Matrix metalloproteinases and metastasis , 1999, Cancer Chemotherapy and Pharmacology.

[37]  P. Ruck,et al.  Nonspecific immunostaining of blast cells of acute leukemia by antibodies against nonhemopoietic antigens. , 1995, Hematologic pathology.