Tracheobronchial involvement in relapsing polychondritis diagnosed on endobronchial ultrasound.

Respiratory tract chondritis is not uncommon in patients with relapsing polychondritis (RP); however, diagnosing this condition remains problematic, especially in patients whose extrapulmonary manifestations do not predominate, as there are broad differential diagnoses of airway obstruction. We herein report the case of a 56-year-old man who presented with cough and dyspnea. Computed tomography of the chest demonstrated diffuse smooth thickening of the visualized tracheobronchial wall with a moderately narrowed lumen. Airway chondritis was diagnosed on endobronchial ultrasound following demonstration of thickening of the submucosal and cartilaginous layers in the anterior and lateral aspects of the bronchial wall, while the posterior region expressed less involvement. In conjunction with nasal and auricular chondritis, which were previously overlooked, RP was finally diagnosed.

[1]  A. Ernst,et al.  Pulmonary manifestations of relapsing polychondritis. , 2010, Clinics in chest medicine.

[2]  U. Heemann,et al.  Relapsing polychondritis: An autoimmune disease with many faces. , 2010, Autoimmunity reviews.

[3]  David L Levin,et al.  Nonneoplastic lesions of the tracheobronchial wall: radiologic findings with bronchoscopic correlation. , 2002, Radiographics : a review publication of the Radiological Society of North America, Inc.

[4]  A. Mehta,et al.  Management of airway manifestations of relapsing polychondritis: case reports and review of literature. , 1999, Chest.

[5]  K. Dohi,et al.  Assessment of usefulness of endobronchial ultrasonography in determination of depth of tracheobronchial tumor invasion. , 1999, Chest.

[6]  C. Marquette,et al.  Respiratory Involvement in Relapsing Polychondritis: Clinical, Functional, Endoscopic, and Radiographic Evaluations , 1998, Medicine.

[7]  Steven F. Isenberg Relapsing Polychondritis , 1997, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[8]  H. Levine,et al.  Relapsing polychondritis — REPORT OF TEN CASES , 1979, The Laryngoscope.

[9]  C. Pearson,et al.  RELAPSING POLYCHONDRITIS: Prospective Study of 23 Patients and A Review of the Literature , 1976, Medicine.

[10]  R. Sato,et al.  A patient with relapsing polychondritis who had been diagnosed as intractable bronchial asthma. , 2012, Internal medicine.

[11]  K. Shibuya,et al.  Correlation between endobronchial ultrasonography (EBUS) images and histologic findings in normal and tumor-invaded bronchial wall. , 2002, Lung cancer.

[12]  H. Becker,et al.  [Endobronchial ultrasound]. , 1997, Pneumologie.