How much sequence information is needed for the regulation of amino-terminal acetylation of eukaryotic proteins?

Abstract A computer program, Pattern Learn, can distinguish between acetylated and non-acetylated proteins by comparing the first 40 residues for their statistical assignment as secondary-structure formers (+), breakers (−) or neutrals (0). The major distinguishing features between acetylated and non-acetylated proteins appear in the sequences ranges 1–10, 16–24 and 30–40, but the precise nature of the distinguishing features is not known.

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