MHC class II proteins and disease: a structural perspective
暂无分享,去创建一个
Lars Fugger | Christian Siebold | E. Yvonne Jones | L. Fugger | J. Strominger | E. Jones | C. Siebold | Jack L. Strominger | E. Jones
[1] C Oseroff,et al. Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones , 1994, The Journal of experimental medicine.
[2] P. Gregersen,et al. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. , 1987, Arthritis and rheumatism.
[3] M. Weinblatt,et al. Rheumatoid arthritis. , 2001, Lancet.
[4] Arne Svejgaard,et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis , 2002, Nature Immunology.
[5] S. Paget,et al. Predominantly T-cell infiltrate in rheumatoid synovial membranes. , 1975, The New England journal of medicine.
[6] Roland Martin,et al. Structure of a human autoimmune TCR bound to a myelin basic protein self‐peptide and a multiple sclerosis‐associated MHC class II molecule , 2005, The EMBO journal.
[7] J. Noseworthy,et al. Multiple sclerosis. , 2002, Annual review of medicine.
[8] J. Todd,et al. HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus , 1987, Nature.
[9] D. Fremont,et al. Structures of an MHC Class II Molecule with Covalently Bound Single Peptides , 1996, Science.
[10] T. Tanaka,et al. Aspartic acid at position 57 of DQβ chain does not protect against Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects , 1989, Diabetologia.
[11] Zhaohui Qian,et al. Arthritic Joints Collagen-Specific Cells and Their Presence in Long-Term Activation of Type II Model of Collagen-Induced Arthritis Reveals T Cell Response in the HLA-DR 1 Mouse Ex Vivo Characterization of the Autoimmune , 2005 .
[12] J. Todd,et al. A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins. , 2001, Human molecular genetics.
[13] A. Sette,et al. Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II Molecule1 , 2003, The Journal of Immunology.
[14] S. Wassertheil-Smoller,et al. A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis. , 1987, The New England journal of medicine.
[15] Don C. Wiley,et al. Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein , 1998, The Journal of experimental medicine.
[16] Emmanuel Mignot,et al. DQ (rather than DR) gene marks susceptibility to narcolepsy , 1992, The Lancet.
[17] N Risch,et al. Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. , 2001, American journal of human genetics.
[18] Y. Iwamoto,et al. Genetic analysis of HLA class II alleles and susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects , 1992, Diabetologia.
[19] Lars Fugger,et al. Specificity of an HLA‐DRB1*0401‐restricted T cell response to type II collagen , 1996, European journal of immunology.
[20] J. Todd,et al. Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models. , 2001, Immunity.
[21] R. Karr,et al. Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association , 1995, The Journal of experimental medicine.
[22] Arne Svejgaard,et al. Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[23] E. Thorsby,et al. T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. , 1994, Human immunology.
[24] A. Woods,et al. An HLA-DR1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II Collagen , 1997, The Journal of experimental medicine.
[25] James J Walters,et al. Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. , 2005, The Journal of clinical investigation.
[26] Don C. Wiley,et al. Complexed with a Peptide from Human Myelin Basic Protein , 1998 .
[27] Don C. Wiley,et al. Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401) , 2002, The Journal of experimental medicine.
[28] E. Bergseng,et al. Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[29] Jennifer Maynard,et al. Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity. , 2005, Immunity.
[30] J. Mussini,et al. [Immunology of multiple sclerosis]. , 1982, La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris.
[31] H. Rammensee,et al. Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides. , 1994, Journal of immunology.
[32] Don C. Wiley,et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide , 1994, Nature.
[33] Richard J Farrell,et al. Celiac sprue. , 2002, The New England journal of medicine.
[34] F. Sinigaglia,et al. Identification of a motif for HLA-DR1 binding peptides using M13 display libraries , 1992, The Journal of experimental medicine.
[35] E. Bergseng,et al. Refining the Rules of Gliadin T Cell Epitope Binding to the Disease-Associated DQ2 Molecule in Celiac Disease: Importance of Proline Spacing and Glutamine Deamidation1 , 2005, The Journal of Immunology.
[36] M. Dougados,et al. Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA 4 Ig , 2003 .
[37] R B Smith,et al. Insulin dependent diabetes mellitus. , 1992, The New Zealand medical journal.
[38] D. Hafler,et al. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope , 2005, Nature.
[39] R. Jonsson,et al. A novel NOD-derived murine model of primary Sjögren's syndrome. , 1998, Arthritis and rheumatism.
[40] Jan Engberg,et al. Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex , 2000, The Journal of experimental medicine.
[41] O. Schueler‐Furman,et al. Examination of possible structural constraints of MHC‐binding peptides by assessment of their native structure within their source proteins , 2001, Proteins.
[42] P. Stastny. Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. , 1978, The New England journal of medicine.
[43] E. Thorsby,et al. Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer , 1989, The Journal of experimental medicine.
[44] E. Mignot,et al. Genetic and familial aspects of narcolepsy , 1998, Neurology.
[45] M. Dougados,et al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. , 2003, The New England journal of medicine.
[46] D. Zaller,et al. Prediction of peptide affinity to HLA DRB1*0401. , 1994, International archives of allergy and immunology.
[47] A. Woods,et al. An HLA-DR 1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II Collagen , 1997 .
[48] R. Karr,et al. Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[49] Don C. Wiley,et al. Structure of a human insulin peptide–HLA-DQ8 complex and susceptibility to type 1 diabetes , 2001, Nature Immunology.
[50] E. Unanue,et al. Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice. , 2000, Immunity.
[51] L. Fugger,et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease , 1998, Nature Medicine.
[52] J. Hillert,et al. The multiple sclerosis- and narcolepsy-associated HLA class II haplotype includes the DRB5*0101 allele. , 1995, Tissue antigens.
[53] Derin B Keskin,et al. Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration of experimental autoimmune encephalomyelitis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[54] D I Stuart,et al. Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A. , 1979, Journal of molecular biology.
[55] J. D. Capra,et al. Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. , 1990, The New England journal of medicine.
[56] W. Kwok,et al. Insulin-Dependent Diabetes Mellitus Molecule Associated with Dominant Protection in MHCHLA-DQA 1 * 0102 / DQB 1 * 0602 , the Class II A Peptide Binding Motif for , 1998 .
[57] L. Fugger,et al. Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[58] Ian A Wilson,et al. Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. , 2003, Journal of molecular biology.
[59] P. Roepstorff,et al. The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase , 2000, The Journal of experimental medicine.
[60] K. Garcia,et al. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. , 2000, Science.
[61] Sebastiaan Overeem,et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains , 2000, Nature Medicine.
[62] L. Fugger,et al. Tracking of Proinflammatory Collagen-Specific T Cells in Early and Late Collagen-Induced Arthritis in Humanized Mice1 , 2004, The Journal of Immunology.
[63] E. Thorsby,et al. Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients , 1993, The Journal of experimental medicine.
[64] D. Zaller,et al. X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II. , 1997, Immunity.
[65] L. Fugger,et al. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor , 1999, Nature Genetics.
[66] F. Koning,et al. Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. , 1998, Journal of immunology.
[67] M. Atkinson,et al. Type 1 diabetes: new perspectives on disease pathogenesis and treatment , 2001, The Lancet.
[68] Sebastiaan Overeem,et al. Hypocretin (orexin) deficiency in human narcolepsy , 2000, The Lancet.
[69] E. Mignot,et al. Clinical aspects of narcolepsy-cataplexy across ethnic groups. , 2002, Sleep.
[70] Silke Schmidt,et al. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. , 2004, American journal of human genetics.
[71] A. Begovich,et al. Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis , 1993, Nature.
[72] K. Wucherpfennig,et al. Unconventional topology of self peptide–major histocompatibility complex binding by a human autoimmune T cell receptor , 2005, Nature Immunology.
[73] D. Wiley,et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 , 1993, Nature.
[74] R. Mariuzza,et al. Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. , 2000, Journal of molecular biology.
[75] Emmanuel Mignot,et al. The role of hypocretins (orexins) in sleep regulation and narcolepsy. , 2002, Annual review of neuroscience.