Cell Cycle and Liver Function

The liver with its multiple functions is one of the most difficult cases to establish the relationship between proliferation and function. Nevertheless, a detailed analysis of the literature shows that some tentative conclusions can be made.

[1]  M. Hoagland,et al.  Patterns of albumin and general protein synthesis in rat liver as revealed by gel electrophoresis. , 1972, Biochimica et biophysica acta.

[2]  H. Busch.  METHODS IN CANCER RESEARCH , 1969 .

[3]  B. Jailkhani,et al.  Induction of phosvitin by oestradiol in rooster liver needs DNA synthesis. , 1972, Nature: New biology.

[4]  F. Swartz,et al.  Evidence for a subpopulation of cells with an extended G2 period in normal adult mouse liver. , 1967, Experimental cell research.

[5]  T. E. Webb,et al.  Temporal Changes in DNA and RNA Synthesis in the Regenerating Liver of Hydrocortisone-treated Rats , 1971 .

[6]  B. Sandstroem,et al.  STUDIES ON CELLS FROM LIVER TISSUE CULTIVATED IN VITRO. I. INFLUENCE OF THE CULTURE METHOD ON CELL MORPHOLOGY AND GROWTH PATTERN. , 1965, Experimental cell research.

[7]  K. Tsukada,et al.  SYNTHESIS OF RIBONUCLEIC ACID BY LIVER NUCLEAR AND NUCLEOLAR PREPARATIONS AFTER PARTIAL HEPATECTOMY. , 1964, The Journal of biological chemistry.

[8]  R. Perry,et al.  Early appearance of histone messenger RNA in polyribosomes of cultured L cells. , 1972, Journal of molecular biology.

[9]  M. Hoagland,et al.  Cytoplasmic control of protein synthesis in rat liver. , 1971, Biochimica et biophysica acta.

[10]  G. Weber.  BEHAVIOR AND REGULATION OF ENZYME SYSTEMS IN NORMAL LIVER AND IN HEPATOMAS OF DIFFERENT GROWTH RATES. , 1963, Advances in enzyme regulation.

[11]  H. Hiatt,et al.  The effects of thymidine administration on thymidylate kinase activity and on DNA synthesis in mammalian tissues. , 1961, Cold Spring Harbor symposia on quantitative biology.

[12]  E. Bresnick,et al.  Inhibition of thymidine kinase activity in liver and hepatomas by TTP and d-CTP. , 1964, Biochemical and biophysical research communications.

[13]  Mueller Gc.  Biochemical events in the animal cell cycle. , 1969 .

[14]  C. Vogel,et al.  Serum alpha-fetoprotein as a biochemical marker for hepatocellular carcinoma. , 1972, Cancer research.

[15]  R. O'Brien,et al.  Chromatin binding of benzo(a)pyrene and 20-methylcholanthrene. , 1969, Biochimica et biophysica acta.

[16]  R. Fuller.  Rhythmic Changes in Enzyme Activity and their Control , 1971 .

[17]  V. Terskikh,et al.  ON THE RESTING PERIODS IN THE CELL LIFE CYCLE * , 1969 .

[18]  B. Sigel.  CHAPTER 15 – EXTRACELLULAR REGULATION OF LIVER REGENERATION , 1972 .

[19]  Abelev Gi.  Alpha-Fetoprotein in Ontogenesis and its Association with Malignant Tumors , 1971 .

[20]  A. Glinos,et al.  Humoral Factors Involved in the Induction of Liver Regeneration in the Rat.∗ † , 1952, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[21]  H. Morris,et al.  Comparison of activity and isozyme patterns of four enzymes from hepatomas of different growth rates. , 1971, Journal of the National Cancer Institute.

[22]  N. Bucher.  REGENERATION OF MAMMALIAN LIVER. , 1963, International review of cytology.

[23]  G. Russev,et al.  Distribution of newly synthesized histones during DNA replication. , 1974, European journal of biochemistry.

[24]  J. M. Llanos,et al.  Twenty-four-hour variations in DNA synthesis of a fast-growing and a slow-growing hepatoma: DNA synthesis rhythm in hepatoma. , 1971, Journal of the National Cancer Institute.

[25]  J. Anderegg,et al.  Nucleic acid metabolism in regenerating rat liver. VII. Effect of x-radiation on enzymes of DNA synthesis. , 1960, Cancer research.

[26]  J. V. van Lancker,et al.  Molecular mechanisms of liver regeneration. VII. Conversion of cytidine to deoxycytidine in rat regenerating livers. , 1969, Archives of biochemistry and biophysics.

[27]  H. Watabe.  Early appearance of embryonic -globulin in rat serum during carcinogenesis with 4-dimethylaminoazobenzene. , 1971, Cancer research.

[28]  H. S. Schwartz,et al.  ACTINOMYCIN D. EFFECTS ON NUCLEIC ACID AND PROTEIN METABOLISM IN INTACT AND REGENERATING LIVER OF RATS. , 1965, Cancer research.

[29]  B Sendov,et al.  Computer simulation of the regenerative processes in the liver. , 1968, Journal of theoretical biology.

[30]  M. Gruber,et al.  Induction of phosvitin synthesis in roosters by estradiol injection. , 1971, Biochimica et biophysica acta.

[31]  J. Grisham.  HEPATOCYTIC PROLIFERATION IN NORMAL RATS AFTER MULTIPLE EXCHANGE TRANSFUSIONS WITH BLOOD FROM PARTIALLY HEPATECTOMIZED RATS , 1969 .

[32]  B. Sigel.  The extracellular regulation of liver regeneration. , 1969, The Journal of surgical research.

[33]  H. Morris,et al.  Induction of tyrosine aminotransferase and amino acid transport in Morris hepatomas and in adult and neonatal rat liver. , 1971, Cancer research.

[34]  E. Frieden,et al.  CHAPTER 1 – Hormonal Responses in Amphibian Metamorphosis , 1970 .

[35]  R T Schimke,et al.  Control of enzyme levels in animal tissues. , 1970, Annual review of biochemistry.

[36]  S. Weinhouse,et al.  Molecular forms of enzymes in cancer. , 1972, Biochimie.

[37]  O. Greengard.  CHAPTER 2 – The Developmental Formation of Enzymes in Rat Liver , 1970 .

[38]  V. Potter,et al.  Effect of cordycepin on induction of tyrosine aminotransferase employing hepatoma cells in tissue culture. , 1972, Experimental cell research.

[39]  Y. Hamashima,et al.  THE LOCALIZATION OF ALBUMIN AND FIBRINOGEN IN HUMAN LIVER CELLS , 1964, The Journal of cell biology.

[40]  M. Barnhart.  Cellular site for prothrombin synthesis. , 1960, The American journal of physiology.

[41]  H. Barbason,et al.  RELATION BETWEEN THE CIRCADIAN RHYTHMS OF MITOTIC RATE AND CHOLESTEROL‐7α‐HYDROXYLASE ACTIVITY IN THE REGENERATING LIVER , 1972, Cell and tissue kinetics.

[42]  N. Bucher,et al.  Regeneration of Rat Liver: Transfer of Humoral Agent by Cross Circulation , 1967, Science.

[43]  A. Guillouzo,et al.  An ultrastructural study of primary cultures of adult human liver tissue. , 1972, Experimental and molecular pathology.

[44]  R. Carriere,et al.  The growth of liver parenchymal nuclei and its endocrine regulation. , 1969, International review of cytology.

[45]  J. M. Llanos,et al.  Assay of plasma from intact and hepatectomized mice on mouse regenerating liver DNA synthesis , 1972, Virchows Archiv. B, Cell pathology.

[46]  R. H. Stellwagen,et al.  Regulation of Specific Protein Synthesis in Eucaryotic Cells , 1970 .

[47]  O. Greengard,et al.  CYTOMORPHOMETRY OF DEVELOPING RAT LIVER AND ITS APPLICATION TO ENZYMIC DIFFERENTIATION , 1972, The Journal of cell biology.

[48]  Lajtha Lg.  ON THE CONCEPT OF THE CELL CYCLE. , 1963 .

[49]  K. Weinbren.  Regeneration of the liver. , 1959, Gastroenterology.

[50]  M. Fujioka,et al.  METABOLISM OF RIBONUCLEIC ACID AFTER PARTIAL HEPATECTOMY. , 1963, The Journal of biological chemistry.

[51]  A. Chedid,et al.  Diurnal Rhythm in Endoplasmic Reticulum of Rat Liver: Electron Microscopic Study , 1972, Science.

[52]  J. Fabrikant.  Size of proliferating pools in regenerating liver. , 1969, Experimental Cell Research.

[53]  W. Rutter,et al.  Toward molecular mechanisms of developmental processes. , 1973, Annual review of biochemistry.

[54]  C. Nadal,et al.  Polyploïdie somatique dans le foie de rat: I. Le rôle des cellules binucléées dans la genèse des cellules polyploïdes , 1966 .

[55]  J. S. Schweppe,et al.  Binding of chemical carcinogens to nuclear proteins of rat liver. , 1972, Cancer research.

[56]  S. Kauffman.  Metabolic stability and epigenesis in randomly constructed genetic nets. , 1969, Journal of theoretical biology.

[57]  J. M. Brown.  Long G1 or G0 state: a method of resolving the dilemma for the cell cycle of an in vivo pfpulation. , 1968, Experimental Cell Research.

[58]  R. Goss,et al.  Regulation of Organ and Tissue Growth , 1971, Science.

[59]  K. Tsukada,et al.  Ribosomal change in liver after partial hepatectomy and acute stress. , 1968, The Journal of biological chemistry.

[60]  G. P. Warwick.  The covalent binding of metabolites of tritiated 2-methyl-4-dimethylamino-azobenzene to rat liver nucleic acids and proteins, and the carcinogenicity of the unlabelled compound in partially hepatectomised rats. , 1967, European journal of cancer.

[61]  D. Franks,et al.  Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA synthesis following partial hepatectomy or hormone infusion. , 1972, Biochemical and biophysical research communications.

[62]  C. A. Nichol,et al.  CHANGES IN ALANINE TRANSAMINASE ACTIVITY RELATED TO CORTICOSTEROID TREATMENT OR CAPACITY FOR GROWTH. , 1963, Advances in enzyme regulation.

[63]  H. Rabes,et al.  Synthesis of RNA, protein, and DNA in the liver of normal and hypophysectomized rats after partial hepatectomy. , 1969, Cancer research.

[64]  J. Grisham.  6 – Effects of Drugs on Hepatic Cell Proliferation , 1973 .

[65]  J. Post,et al.  CHANGES IN THE REPLICATION TIMES AND PATTERNS OF THE LIVER CELL DURING THE LIFE OF THE RAT. , 1964, Experimental cell research.

[66]  R. Cahn,et al.  Heritability of cellular differentiation: clonal growth and expression of differentiation in retinal pigment cells in vitro. , 1966, Proceedings of the National Academy of Sciences of the United States of America.

[67]  I. Cameron,et al.  Drugs and the cell cycle , 1973 .

[68]  B. Follett,et al.  The vitellogenic response in the south african clawed toad (Xenopus laevis daudin) , 1968, Journal of cellular physiology.

[69]  E. Ivanova,et al.  Cell cycle dependent turnover of non-histone proteins in chromatin. , 1974, Experimental cell research.

[70]  G. Novelli,et al.  EFFECT OF ACTINOMYCIN D ON THE SYNTHESIS OF DNA POLYMERASE IN HEPATECTOMIZED RATS. , 1963, Biochemical and biophysical research communications.

[71]  H. Pitot.  Some aspects of the developmental biology of neoplasia. , 1968, Cancer research.

[72]  T. Umeda,et al.  Relationship between the ribosomal alteration after partial hepatectomy and the increase in liver protein synthesis in vivo. , 1968, The Journal of biological chemistry.

[73]  R. Goutier,et al.  Effects of Total-Body X-Irradiation and AET on the Activity of Thymidine-Phosphorylating Kinases during Liver Regeneration , 1967 .

[74]  N. Fausto,et al.  MOLECULAR MECHANISMS OF LIVER REGENERATION. IV. THYMIDYLIC KINASE AND DEOXYRIBONUCLEIC ACID POLYMERASE ACTIVITIES IN NORMAL AND REGENERATING LIVER. , 1965, The Journal of biological chemistry.

[75]  Kaighn Me,et al.  Production of Albumin and Other Serum Proteins by Clonal Cultures of Normal Human Liver , 1971 .

[76]  J. Grisham,et al.  A morphologic study of deoxyribonucleic acid synthesis and cell proliferation in regenerating rat liver; autoradiography with thymidine-H3. , 1962, Cancer research.

[77]  L. Djondjurov,et al.  Distribution of tryptophan-containing proteins and of newly synthesized RNA in metaphase chromosomes. An autoradiographic study. , 1972, Experimental cell research.

[78]  N. Bucher,et al.  Regeneration of liver and kidney , 1971 .

[79]  C. Grobstein.  Differentiation of Vertebrate Cells , 1959 .

[80]  S. Hayashi,et al.  Diurnal change in ornithine decarboxylase activity of rat liver. , 1972, Biochemical and biophysical research communications.

[81]  R. Wallace,et al.  On the site of phosvitin synthesis in Xenopus laevis. , 1968, Biochimica et biophysica acta.

[82]  J. Post,et al.  THE REPLICATION TIME AND PATTERN OF CARCINOGEN-INDUCED HEPATOMA CELLS , 1964, The Journal of cell biology.

[83]  N. Bucher,et al.  Nucleotide pools and [6-14C]orotic acid incorporation in early regenerating rat liver. , 1966, Biochimica et biophysica acta.

[84]  G. Georgiev,et al.  On the structural organization of operon and the regulation of RNA synthesis in animal cells. , 1969, Journal of theoretical biology.

[85]  J. Jost,et al.  Deoxyribonucleic acid and ribonucleic acid synthesis during phosvitin induction by 17beta-estradiol in immature chicks. , 1973, The Journal of biological chemistry.

[86]  E. Leduc.  CHAPTER 14 – REGENERATION OF THE LIVER , 1964 .

[87]  C. Nadal.  SYNCHRONIZATION OF BABY RAT HEPATOCYTES: A NEW TEST FOR THE DETECTION OF FACTORS CONTROLLING DNA SYNTHESIS IN RAT HEPATIC CELLS , 1973, Cell and tissue kinetics.

[88]  N. Fausto,et al.  MOLECULAR MECHANISM OF LIVER REGENERATION. THE EFFECT OF PUROMYCIN OF DEOXYRIBONUCLEIC ACID SYNTHESIS. , 1964, The Journal of biological chemistry.

[89]  H. Morris,et al.  Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver. , 1971, Cancer research.

[90]  R. F. Brown,et al.  Effect of inhibitors of protein synthesis on DNA formation in liver. , 1970, Biochimica et Biophysica Acta.

[91]  W. Schmid,et al.  On the mechanism of hormone action. VIII. Further studies on the effect of cortisol on isolated rat-liver nuclei , 1967 .

[92]  M. Takeichi,et al.  THE EXPRESSION OF DIFFERENTIATION BY CHICKEN LENS EPITHELIUM IN IN VITRO CELL CULTURE * , 1971, Development, growth & differentiation.

[93]  B. Sendov,et al.  Possible molecular mechanism for cell differentiation in multicellular organisms. , 1971, Journal of theoretical biology.

[94]  G. P. Warwick,et al.  Liver regeneration and induction of hepatomas in B6AF mice by urethan. , 1970, Cancer research.

[95]  B. Mccarthy,et al.  Ribonucleic acid synthesis in regenerating and embryonic liver. I. The synthesis of new species of RNA during regeneration of mouse liver after partial hepatectomy. , 1967, Journal of molecular biology.

[96]  V. Potter.  Summary of discussion on neoplasms. , 1968, Cancer research.

[97]  J. Meldolesi,et al.  The induction of drug-metabolizing enzymes in rat liver during growth and regeneration. A biochemical and ultrastructural study. , 1967, Laboratory investigation; a journal of technical methods and pathology.

[98]  B. Fisher,et al.  ULTRASTRUCTURAL HEPATIC CHANGES FOLLOWING PARTIAL HEPATECTOMY AND PORTACAVAL SHUNT IN THE RAT. , 1963, Laboratory investigation; a journal of technical methods and pathology.

[99]  P. Dustin.  CELL DIFFERENTIATION AND CARCINOGENESIS: A CRITICAL REVIEW * , 1972, Cell and tissue kinetics.

[100]  C. Epstein,et al.  Cell size, nuclear content, and the development of polyploidy in the Mammalian liver. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[101]  R. Wallace,et al.  The induced synthesis and transport of yolk proteins and their accumulation by the oocyte in Xenopus laevis , 1968, Journal of cellular physiology.

[102]  C. Monder,et al.  Influence of cortisol on glycogen synthesis and gluconeogenesis in fetal rat liver in organ culture. , 1972, The Journal of biological chemistry.

[103]  R. Britten,et al.  Gene regulation for higher cells: a theory. , 1969, Science.

[104]  I. Cameron,et al.  Developmental aspects of the cell cycle , 1971 .

[105]  J. W. Steiner,et al.  Cell population dynamics in the liver. A review of quantitative morphological techniques applied to the study of physiological and pathological growth. , 1966, Experimental and molecular pathology.

[106]  F. Bergel.  NORMAL AND MALIGNANT GROWTH , 1961 .

[107]  T. Argyris,et al.  The stimulation of liver growth and demethylase activity following phenobarbital treatment. , 1968, Developmental biology.

[108]  T. Guiney,et al.  Regeneration of the Liver in Triturus viridescens. ∗ , 1962 .

[109]  S. Gelfant,et al.  Initiation of mitosis in relation to the cell division cycle. , 1962, Experimental cell research.

[110]  H. Klemperer,et al.  Thymidine kinase in rat liver during development. , 1968, The Biochemical journal.

[111]  K. Weinbren,et al.  Hypoglycaemia and the delayed proliferative response after subtotal hepatectomy. , 1972, British journal of experimental pathology.

[112]  B. Sigel,et al.  Effect of blood flow reversal in liver autotransplants upon the site of hepatocyte regeneration. , 1968, The Journal of clinical investigation.

[113]  M. Kumegawa,et al.  THE CIRCUMFUSION SYSTEM FOR MULTIPURPOSE CULTURE CHAMBERS , 1968, The Journal of cell biology.

[114]  J. Grisham.  Cellular Proliferation in the Liver , 1969 .

[115]  J. Uriel,et al.  Antigènes cellulaires transitoires du foie de rat. I. Sécrétion et synthèse des protéines sériques fetospécifiques au cours du développement et de la régénération hépatiques , 1971 .

[116]  M. Epstein,et al.  Control of Cellular Growth in Adult Organisms. , 1968 .

[117]  J. Grisham,et al.  EFFECT OF PARTIAL HEPATECTOMY ON DNA SYNTHESIS AND MITOSIS IN HETEROTOPIC PARTIAL AUTOGRAFTS OF RAT LIVER. , 1964, Cancer research.

[118]  Pamela J. Hines,et al.  REPAIR and regeneration. , 1959, Laboratory investigation; a journal of technical methods and pathology.

[119]  J. Post,et al.  THE REPLICATION TIME AND PATTERN OF THE LIVER CELL IN THE GROWING RAT , 1963, The Journal of cell biology.

[120]  W. D. Wicks.  Induction of tyrosine-alpha-ketoglutarate transaminase in fetal rat liver. , 1968, The Journal of biological chemistry.

[121]  M. Smith,et al.  STUDIES ON THE MECHANISM OF DIETHYLSTILBESTROL-INDUCED FORMATION OF PHOSPHOPROTEIN IN MALE CHICKENS. , 1964, The Journal of biological chemistry.

[122]  O. Greengard.  Enzymic Differentiation in Mammalian Liver , 1969 .

[123]  M. Hoagland,et al.  Physiology of rat-liver polysomes. Protein synthesis by stable polysomes. , 1967, The Biochemical journal.

[124]  B. Sendov,et al.  A model of the regulatory mechanism of cellular multiplication. , 1966, Journal of theoretical biology.

[125]  I. Tedo,et al.  Hepatic Regeneration: Effect of Size of Resection on in vitro Growth of Remnant Liver Cells , 1968, Nature.

[126]  V. Potter,et al.  Nucleic Acid Metabolism in Regenerating Rat Liver , 1956 .

[127]  T. Argyris.  Additive effects of phenobarbital and high protein diet on liver growth in immature male rats. , 1971, Developmental biology.

[128]  J. Roth.  INCREASED STABILITY OF TEMPLATES FOR SOME ENZYMES OF DNA SYNTHESIS IN TUMORS: DEOXYCYTIDYLATE DEAMINASE, THYMIDINE AND THYMIDYLATE KINASE. , 1964, Life sciences.

[129]  F. Kenney,et al.  Regulation of yolk protein synthesis in amphibian liver. I. Induction of lipovitellin synthesis by estrogen. , 1972, Biochimica et biophysica acta.

[130]  P. Perlmann,et al.  Synthesis of stage specific serum proteins and tissue antigens by early neonatal rat liver. , 1968, Experimental cell research.

[131]  H. Sidransky,et al.  Studies on the turnover of mRNA in free and membrane-bound polyribosomes in rat liver. , 1972, Biochimica et biophysica acta.

[132]  R. Lesch,et al.  THE DISTRIBUTION OF ALBUMIN SYNTHESIS THROUGHOUT THE LIVER LOBULE , 1970, The Journal of cell biology.

[133]  Y. Moulé.  Endoplasmic Reticulum and Microsomes of Rat Liver , 1964 .

[134]  Laws Jo.  Tissue regeneration and tumour development. , 1959 .

[135]  E. Farber,et al.  The effects of cycloheximide on the cell cycle of the regenerating rat liver. , 1969, Laboratory investigation; a journal of technical methods and pathology.

[136]  B. Schultze,et al.  PROLIFERATION OF LIVER EPITHELIA IN THREE‐WEEK‐OLD RATS , 1973, Cell and tissue kinetics.

[137]  P. Karlson,et al.  On the mechanism of hormone action. 13. Stimulating effects of ecdysone, juvenile hormone and ions on RNA synthesis in fat body cell nuclei from Calliphora erythrocephala isolated by a filtration technique. , 1969, Experimental cell research.

[138]  W. Heine,et al.  Regeneration of kidney parenchyma under normal and pathological conditions. , 1972, Beitrage zur Pathologie.

[139]  L. Gerschenson,et al.  Tyrosine Transaminase Induction by Dexamethasone in a New Rat Liver Cell Line , 1970, Science.

[140]  J. Baxter,et al.  Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells. , 1972, Nature: New biology.

[141]  D. K. Myers,et al.  Deoxycytidylate deaminase levels in regenerating rat liver. , 1961, Canadian journal of biochemistry and physiology.

[142]  Michael Locke,et al.  Cellular membranes in development , 1964 .

[143]  I. Black,et al.  CHAPTER 4 – The Regulation of Some Biochemical Circadian Rhythms , 1970 .

[144]  J. Fouts,et al.  The metabolism of drugs by regenerating liver. , 1961, Biochemical pharmacology.

[145]  W. Verly,et al.  The hepatic chalone. I. Assay method for the hormone and purification of the rabbit liver chalone. , 1971, Canadian journal of biochemistry.

[146]  H. Maeno,et al.  Impairment of albumin synthesis in cell‐free systems from rat liver , 1970, FEBS letters.

[147]  F. Kenney,et al.  EFFECT OF PUROMYCIN ON DEOXYRIBONUCLEIC ACID SYNTHESIS BY REGENERATING RAT LIVER. , 1964, Biochimica et biophysica acta.

[148]  I. Irlin,et al.  [EMBRYONAL SERUM ALPHA- GLOBULIN AND ITS SYNTHESIS BY TRANSPLANTABLE MOUSE HEPATOMAS]. , 1963, Biokhimiia.

[149]  K. Seifart,et al.  Inhibition by α‐amanitin of induction of tyrosine transaminase in rat liver by cortisol , 1970 .

[150]  A. Glinos.  ENVIRONMENTAL FEEDBACK CONTROL OF CELL DIVISION , 1960, Annals of the New York Academy of Sciences.

[151]  H. Marquardt,et al.  DNA binding and inhibition of DNA synthesis after 7,12-dimethylbenz(a)anthracene administered during the early prereplicative phase in regenerating rat liver. , 1972, Cancer research.

[152]  K. Tsukada,et al.  Liver protein synthesis after partial hepatectomy and acute stress. , 1967, The Journal of biological chemistry.

[153]  A. Sartorelli,et al.  Induction of phenobarbital of microsomal mixed oxidase enzymes in regenerating rat liver. , 1970, The Journal of biological chemistry.

[154]  P. Perlmann,et al.  Antigen development in neonatal rat liver. , 1968, Experimental cell research.

[155]  G. Williams,et al.  Early appearance of serum -fetoprotein during hepatocarcinogenesis as a function of age of rats and extent of treatment with 3'-methyl-4-dimethylaminoazobenzene. , 1972, Cancer research.

[156]  J. Uriel.  Transitory liver antigens and primary hepatoma in man and rat. , 1969, Pathologie-biologie.

[157]  A. H. Gordon,et al.  Plasma protein synthesis by the isolated perfused regenerating rat liver. , 1966, Biochimica et biophysica acta.

[158]  G. Weber,et al.  Glucose-6-phosphatase activity in normal, pre-cancerous, and neoplastic tissues. , 1955, Cancer research.

[159]  H. Terayama,et al.  Pattern of 2-methyl-4-dimethylaminoazobenzene-binding proteins in the livers of partially hepatectomized rats and of continuously dye-fed rats in comparison with 3'-methyl-4-dimethylaminoazobenzene. , 1972, Cancer research.

[160]  H. Green,et al.  Stimulation of RNA synthesis and cell division in resting cells by a factor present in serum. , 1967, The Wistar Institute symposium monograph.

[161]  P. Campbell.  Functions of polyribosomes attached to membranes of animal cells , 1970, FEBS letters.

[162]  J. Whitfield,et al.  Parathyroid Hormone: A Possible Initiator of Liver Regeneration 1 , 1972, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[163]  K. Jeejeebhoy,et al.  The effect of cortisol on the synthesis of rat plasma albumin, fibrinogen and transferrin. , 1972, The Biochemical journal.

[164]  W. Rutter,et al.  ENZYME VARIANTS AND METABOLIC DIVERSIFICATION. , 1963, Advances in enzyme regulation.

[165]  H. Terayama,et al.  The nature of inhibitors of DNA synthesis in rat-liver hepatoma cells. , 1969, Biochimica et biophysica acta.

[166]  Alexander Rw,et al.  Explant culture of rat liver. I. Method, morphology, and cytogenesis. , 1970 .

[167]  P. Nowell,et al.  Radiation carcinogenesis: the sequence of events. , 1965, Science.

[168]  R. Freedland,et al.  Control of Enzyme Activity: Nutritional Factors1 , 1971 .

[169]  H. Gelboin.  Carcinogens, enzyme induction, and gene action. , 1967, Advances in cancer research.

[170]  G. Johnson,et al.  Differentiation of the mammalian hepatic primordium in vitro. I. Morphogenesis and the onset of haematopoiesis. , 1973, Journal of embryology and experimental morphology.

[171]  F. Bresciani.  Cell proliferation in cancer. , 1968, European journal of cancer.

[172]  H. Coon.  Clonal stability and phenotypic expression of chick cartilage cells in vitro. , 1966, Proceedings of the National Academy of Sciences of the United States of America.

[173]  H. Sugano,et al.  α‐fetoprotein and hepatocarcinogenesis in rats fed 3′‐methyl‐4‐(dimethylamino)azobenzene or n‐2‐fluorenylacetamide , 1972, International journal of cancer.

[174]  V. I. Guelstein,et al.  ANTIGENIC STRUCTURE OF MOUSE HEPATOMAS. V. ORGANOSPECIFIC LIVER ANTIGENS AND EMBRYONIC ALPHA-GLOBULIN IN HEPATOMAS OF MICE INDUCED WITH ORTHOAMINOAZOTOLUENE (AAT). , 1965, Neoplasma.

[175]  C. Markert.  Neoplasia: a disease of cell differentiation. , 1968, Cancer research.

[176]  J. Jaffe,et al.  Diurnal mitotic periodicity in regen erating rat liver , 1954, The Anatomical record.

[177]  Miloslav (Mila). Rechcigl.  Enzyme synthesis and degradation in mammalian systems , 1971 .

[178]  J. Post,et al.  Further studies on the replication of rat liver cells in vivo. , 1965, Experimental cell research.

[179]  E. H. Creaser,et al.  Nucleoproteins in regenerating rat liver I. Incorporation of 32P1 into the ribonucleic acid of liver during the early stages of regeneration , 1963 .

[180]  E. Luria,et al.  Differentiation of hepatic and hematopoietic cells and synthesis of blood serum proteins in organ cultures of the liver. , 1969, Experimental cell research.

[181]  S. Adelstein,et al.  Failure of x-rays and actinomycin D to prevent the response of renal and hepatic thymidylate kinase to thymidine treatment in vivo. , 1967, Biochimica et biophysica acta.

[182]  H. Tuczek,et al.  Quantitative autoradiographische Untersuchung zur Heterogenität der Leberzellproliferation nach partieller Hepatektomie , 1970, Virchows Archiv B Cell Pathology.

[183]  P. G. Popov,et al.  Effect of olivomycin on the induced synthesis of tyrosine aminotransferase and tryptophan oxygenase in rat liver. , 1973, Biochemical pharmacology.

[184]  H. Pitot.  Some Biochemical Aspects of Malignancy , 1966 .

[185]  K. Scherrer,et al.  Messenger RNA in avian erythroblasts at the transcriptional and translational levels and the problem of regulation in animal cells , 1968, Journal of cellular physiology.

[186]  J. Paul.  Biochemistry of cell differentiation II , 1977 .

[187]  A. Conney,et al.  INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS. , 1963, Advances in enzyme regulation.

[188]  W. Bullough.  Mitotic and functional homeostasis: a speculative review. , 1965, Cancer research.

[189]  M. Stoker.  Growth regulating substances for animal cells in culture. Introduction. , 1967, The Wistar Institute symposium monograph.

[190]  W. Verly.  The hepatic chalone. , 1973, National Cancer Institute monograph.

[191]  M. Fogel,et al.  Phenotypic changes in cultured hamster embryonic liver cells as studied by immunofluorescence. , 1968, Developmental biology.

[192]  H. Curtis,et al.  Tumor induction as a measure of genetic damage and repair in somatic cells of mice. , 1968, Radiation research.

[193]  J. Tata.  CHAPTER 3 – Regulation of Protein Synthesis by Growth and Developmental Hormones , 1970 .

[194]  I. Cameron,et al.  8 – Relationship between Cell Proliferation and Gytodifferentiation in Embryonic Chick Tissues , 1971 .

[195]  R. Hoffenberg,et al.  Regulation of Albumin Synthesis and Catabolism by Alteration of Dietary Protein , 1968, Nature.

[196]  B. Mccarthy,et al.  Ribonucleic acid synthesis in regenerating and embryonic liver. II. The synthesis of RNA during embryonic liver development and its relationship to regenerating liver. , 1967, Journal of molecular biology.

[197]  A. Erslev,et al.  Cellular Response to Partial Hepatectomy , 1963, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.