Synthesis , characterization and antimicrobial screening of some novel coumarin-pyrazolo Schiff bases

Some novel coumarin-pyrazolo substituted Schiff bases were synthesized by two different methods; conventional and microwave irradiation from coumarin-pyrazole aldehyde and different substituted aryl amines. The structure conformation of these synthesized compounds was done by FT-IR, 1 H NMR, 13 C NMR and mass spectral data. All these synthesized compounds were also tested for in-vitro antimicrobial activity against some bacterial as well as fungal strains in DMF and DMSO. It is observed that some of Schiff bases showed excellent antibacterial activity in both solvents.

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