Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

[1]  N. Huntington The unconventional expression of IL‐15 and its role in NK cell homeostasis , 2014, Immunology and cell biology.

[2]  W. El-Deiry,et al.  Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis , 2013, PloS one.

[3]  Susan M. Schlenner,et al.  Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells , 2013, Nature Immunology.

[4]  G. Lenz,et al.  MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma , 2013, Leukemia.

[5]  Stefan P. Glaser,et al.  Mcl-1 is essential for the survival of plasma cells , 2013, Nature Immunology.

[6]  R. Locksley,et al.  Innate lymphoid cells — a proposal for uniform nomenclature , 2013, Nature Reviews Immunology.

[7]  Daniel P. Stewart,et al.  Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration , 2012, Nature Cell Biology.

[8]  Hergen Spits,et al.  Innate lymphoid cells: emerging insights in development, lineage relationships, and function. , 2012, Annual review of immunology.

[9]  Sharline Madera,et al.  The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. , 2012, Immunity.

[10]  Erinna F. Lee,et al.  Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. , 2012, Genes & development.

[11]  Y. Kerdiles,et al.  Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor , 2011, Proceedings of the National Academy of Sciences.

[12]  S. Carotta,et al.  Identification of the earliest NK-cell precursor in the mouse BM. , 2011, Blood.

[13]  C. Libert,et al.  Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? , 2011, Trends in microbiology.

[14]  E. Casanova,et al.  A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development. , 2011, Blood.

[15]  Stefan P. Glaser,et al.  Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory , 2010, Science.

[16]  C. Scott,et al.  Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance. , 2010, Blood.

[17]  A. Strasser,et al.  Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development , 2010, Nature Immunology.

[18]  C. Roth,et al.  Maturation of mouse NK cells is a 4-stage developmental program. , 2009, Blood.

[19]  Yili Yang,et al.  Interleukin-15 enhances proteasomal degradation of bid in normal lymphocytes: implications for large granular lymphocyte leukemias. , 2009, Cancer research.

[20]  J. D. Di Santo,et al.  IL-15 trans-presentation promotes human NK cell development and differentiation in vivo , 2009, The Journal of experimental medicine.

[21]  M. Colonna,et al.  DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors , 2008, The Journal of experimental medicine.

[22]  Christopher E. Clarke A Question of Balance , 2008 .

[23]  T. Sayers,et al.  Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation. , 2008, Blood.

[24]  R. Sun,et al.  Bcl-xL is associated with the anti-apoptotic effect of IL-15 on the survival of CD56(dim) natural killer cells. , 2008, Molecular immunology.

[25]  M. Opp,et al.  Modeling sepsis in the laboratory: merging sound science with animal well-being. , 2008, Comparative medicine.

[26]  J. Opferman,et al.  Apoptosis in the development of the immune system , 2008, Cell Death and Differentiation.

[27]  N. Huntington,et al.  Developmental pathways that generate natural-killer-cell diversity in mice and humans , 2007, Nature Reviews Immunology.

[28]  A. Strasser,et al.  Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 , 2007, Nature Immunology.

[29]  D. Levy,et al.  The molecular basis of IL-21-mediated proliferation. , 2007, Blood.

[30]  K. Fairfax,et al.  NK Cell Maturation and Peripheral Homeostasis Is Associated with KLRG1 Up-Regulation1 , 2007, The Journal of Immunology.

[31]  J. P. Santo NATURAL KILLER CELL DEVELOPMENTAL PATHWAYS: A Question of Balance , 2006 .

[32]  M. Smyth,et al.  CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity1 , 2006, The Journal of Immunology.

[33]  S. Nutt,et al.  A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells , 2005, The Journal of experimental medicine.

[34]  A. Strasser The role of BH3-only proteins in the immune system , 2005, Nature Reviews Immunology.

[35]  S. Korsmeyer,et al.  Obligate Role of Anti-Apoptotic MCL-1 in the Survival of Hematopoietic Stem Cells , 2005, Science.

[36]  Michelle M. Sandau,et al.  Cutting Edge: Transpresentation of IL-15 by Bone Marrow-Derived Cells Necessitates Expression of IL-15 and IL-15Rα by the Same Cells1 , 2004, The Journal of Immunology.

[37]  M. Cooper,et al.  Recognition strategies in the innate immune system of ancestral chordates. , 2004, Molecular immunology.

[38]  P. Burkett,et al.  Coordinate Expression and Trans Presentation of Interleukin (IL)-15Rα and IL-15 Supports Natural Killer Cell and Memory CD8+ T Cell Homeostasis , 2004, The Journal of experimental medicine.

[39]  P. Ramchandani,et al.  A question of balance , 2004, Nature.

[40]  B. Rinkevich Primitive immune systems: Are your ways my ways? , 2004, Immunological reviews.

[41]  S. Korsmeyer,et al.  Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1 , 2003, Nature.

[42]  J. D. Di Santo,et al.  IL-15 is an essential mediator of peripheral NK-cell homeostasis. , 2003, Blood.

[43]  P. Burkett,et al.  Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice , 2003, The Journal of experimental medicine.

[44]  M. Caligiuri,et al.  In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. , 2002, Blood.

[45]  T. Waldmann,et al.  IL-15Rα Recycles and Presents IL-15 In trans to Neighboring Cells , 2002 .

[46]  W. Yokoyama,et al.  In vivo developmental stages in murine natural killer cell maturation , 2002, Nature Immunology.

[47]  K. Kärre NK Cells, MHC Class I Molecules and the Missing Self , 2002, Scandinavian journal of immunology.

[48]  Adelheid Cerwenka,et al.  Natural killer cells, viruses and cancer , 2001, Nature Reviews Immunology.

[49]  Shankar Srinivas,et al.  Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.

[50]  L. Hennighausen,et al.  Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. , 2000, Development.

[51]  J. Lammers,et al.  Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1 , 2000, Current Biology.

[52]  P. Morrissey,et al.  Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice , 2000, The Journal of experimental medicine.

[53]  S. Moro,et al.  DNA Binding Site Selection of Dimeric and Tetrameric Stat5 Proteins Reveals a Large Repertoire of Divergent Tetrameric Stat5a Binding Sites , 2000, Molecular and Cellular Biology.

[54]  M. Smyth,et al.  Accessory function for NK1.1+ natural killer cells producing interferon-gamma in xenospecific cytotoxic T lymphocyte differentiation. , 1999, Transplantation.

[55]  J. D. Di Santo,et al.  Dissecting NK cell development using a novel alymphoid mouse model: investigating the role of the c-abl proto-oncogene in murine NK cell differentiation. , 1999, Journal of immunology.

[56]  W. Leonard,et al.  Stat5b Is Essential for Natural Killer Cell–mediated Proliferation and Cytolytic Activity , 1998, The Journal of experimental medicine.

[57]  T. Dassopoulos,et al.  IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. , 1998, Immunity.

[58]  A. Yoshimura,et al.  Proteasomes Regulate Erythropoietin Receptor and Signal Transducer and Activator of Transcription 5 (STAT5) Activation , 1998, The Journal of Biological Chemistry.

[59]  I. Weissman,et al.  Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow , 1997, Cell.

[60]  T. Mak,et al.  Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor β Chain , 1997, The Journal of experimental medicine.

[61]  M. Armant,et al.  IL-2 and IL-7 but not IL-12 protect natural killer cells from death by apoptosis and up-regulate bcl-2 expression. , 1995, Immunology.

[62]  W. Murphy,et al.  Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized , 1987, The Journal of experimental medicine.

[63]  E. Lotzová,et al.  PREVENTION OF REJECTION OF ALLOGENEIC BONE MARROW TRANSPLANTS BY NK 1.1 ANTISERUM , 1983, Transplantation.

[64]  D. Rittirsch,et al.  Immunodesign of experimental sepsis by cecal ligation and puncture , 2008, Nature Protocols.

[65]  J. D. Di Santo Natural killer cell developmental pathways: a question of balance. , 2006, Annual review of immunology.

[66]  T. Waldmann,et al.  IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. , 2002, Immunity.

[67]  T. Waldmann,et al.  The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. , 1999, Annual review of immunology.

[68]  W. Leonard,et al.  Jaks and STATs: biological implications. , 1998, Annual review of immunology.

[69]  S. Jiang,et al.  Bcl-2 is expressed in human natural killer cells and is regulated by interleukin-2. , 1996, Natural immunity.