The ascending fiber projections from the principal sensory trigeminal nucleus in the rat

Persisting reports of uncrossed secondary trigeminothalamic pathways originating from the principal sensory trigeminal nucleus (PrV) are based mainly on data obtained from surgically induced lesions analyzed by methods other than reduced silver impregnation techniques. After complete stereotaxic or direct surgical lesions of PrV, degenerating fibers proceed ventrally and rostrally from the nucleus and cross the midline in the rostral pons, completing their decussation caudal to nucleus interpeduncularis. These fibers form a large trigeminal lemniscus that ascends through the midbrain dorsomedial to the smaller medial lemniscus. PrV fibers terminate in the posterior thalamic nucleus and throughout the medial two‐thirds of the ventrobasal thalamic complex (VBm) contralateral to the side of the lesion. Connections with the ventral part of zona incerta were also found similar to those reported for the medial lemniscus.

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