Cancer laser therapy using gold nanoparticles

Abstract: In the chapter we describe the possibilities for enhancement of the efficacy of laser selective photothermolysis and hyperthermia mediated by gold nanoparticles (of various shape/size and surface modification) for treatment of tumors. It is shown that unique optical properties of plasmon-resonant nanoparticles open new applications in photothermal therapy. The absorption coefficient of gold nanoparticles near the plasmon resonance is four/six orders of magnitude greater than that of other organic labels and photosensitizers. In addition, gold nanoparticles are photostable and nontoxic, and they can be easily conjugated to antibodies or proteins.

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