Orally administered kappa as well as mu opiate agonists delay gastrointestinal transit time in the guinea pig.

[1]  J. Woods,et al.  Independent central and peripheral mediation of morphine-induced inhibition of gastrointestinal transit in rats. , 1986, The Journal of pharmacology and experimental therapeutics.

[2]  M. Sheehan,et al.  Determination of the receptor selectivity of opioid agonists in the guinea‐pig ileum and mouse vas deferens by use of β‐funaltrexamine , 1985, British journal of pharmacology.

[3]  J. Mccall,et al.  [3H]U-69593 a highly selective ligand for the opioid κ receptor , 1985 .

[4]  E. J. Simon,et al.  Etorphine pharmacokinetics in the rat: Experimental data and mathematical model , 1984, Neuropeptides.

[5]  A. Tavani,et al.  The opioid κ‐selective compound U−50,488H does not inhibit intestinal propulsion in rats , 1984 .

[6]  T. Yaksh,et al.  In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical and cutaneous thermal stimuli in the rat. , 1984, The Journal of pharmacology and experimental therapeutics.

[7]  P. Ferretti,et al.  Morphine tissue levels and reduction of gastrointestinal transit in rats. Correlation supports primary action site in the gut. , 1983, Gastroenterology.

[8]  E. J. Simon,et al.  Receptor affinity and pharmacological potency of a series of narcotic analgesic, anti-diarrheal and neuroleptic drugs. , 1977, European journal of pharmacology.

[9]  John Hughes,et al.  Endogenous opioid peptides: multiple agonists and receptors , 1977, Nature.

[10]  C. Klaassen,et al.  First-pass effect of morphine in rats. , 1977, The Journal of pharmacology and experimental therapeutics.

[11]  A. Takemori,et al.  Studies on the narcotic receptor in the guinea-pig ileum. , 1976, The Journal of pharmacology and experimental therapeutics.

[12]  Hyde Jl.  The use of solid carbon dioxide for producing short periods of anesthesia in guinea pigs. , 1962 .