Near Room Temperature Cross‐Coupling Reactions of Arene Boronic Acids with a Quinoxaline 1,4‐Dioxide Benzylsulfanyl Derivative

A new quinoxaline 1,4-dioxide benzylsulfanyl derivative was tested under mild conditions in copper-mediated Liebeskind–Srogl (LS) cross-coupling reactions with arene boronic acids. These first organometallic cross-coupling reactions performed on a quinoxaline 1,4-dioxide derivative open new perspectives in medicinal chemistry. They represent also the first LS cross-couplings run with an electrophile equipped with an aryl N-oxide moiety.

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