Regulation of interleukin-1β by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: Endogenous neuroprotection

[1]  Volker K. H. Sonntag,et al.  A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury , 2010 .

[2]  D. McAdoo,et al.  Glutamate-induced losses of oligodendrocytes and neurons and activation of caspase-3 in the rat spinal cord , 2008, Neuroscience.

[3]  A. Kavanaugh.  Anakinra (Interleukin-1 Receptor Antagonist) has positive effects on function and quality of life in patients with rheumatoid arthritis , 2006, Advances in therapy.

[4]  Xiao-Ming Xu,et al.  Upregulation of type I interleukin−1 receptor after traumatic spinal cord injury in adult rats , 2006, Acta Neuropathologica.

[5]  S. Lipton.  Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond , 2006, Nature Reviews Drug Discovery.

[6]  N. Rothwell,et al.  A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients , 2005, Journal of Neurology, Neurosurgery & Psychiatry.

[7]  D. McAdoo,et al.  Administration of glutamate into the spinal cord at extracellular concentrations reached post-injury causes functional impairments , 2005, Neuroscience Letters.

[8]  N. Rothwell,et al.  Interleukin-1 and neuronal injury , 2005, Nature Reviews Immunology.

[9]  Xin-jia Wang,et al.  Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury , 2005, Acta Pharmacologica Sinica.

[10]  T. Kupper,et al.  Counter-Regulation of Interleukin-1α (IL-1α) and IL-1 Receptor Antagonist in Murine Keratinocytes , 2005 .

[11]  David J. McAdoo,et al.  Concentrations of glutamate released following spinal cord injury kill oligodendrocytes in the spinal cord , 2004, Experimental Neurology.

[12]  C. Sommer,et al.  Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia , 2004, Neuroscience Letters.

[13]  P. Blumbergs,et al.  Early Expression and Cellular Localization of Proinflammatory Cytokines Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-&agr; in Human Traumatic Spinal Cord Injury , 2004, Spine.

[14]  M. Schultzberg,et al.  Inflammatory mechanisms associated with brain damage induced by kainic acid with special reference to the interleukin‐1 system , 2003, Journal of cellular and molecular medicine.

[15]  Alexander Sasha Rabchevsky,et al.  Experimental modeling of spinal cord injury: characterization of a force-defined injury device. , 2003, Journal of neurotrauma.

[16]  K. Iverfeldt,et al.  Increased sensitivity to N-methyl-d-aspartate receptor-induced excitotoxicity in cerebellar granule cells from interleukin-1 receptor type I-deficient mice , 2002, Journal of Neuroimmunology.

[17]  W. Arend.  The balance between IL-1 and IL-1Ra in disease. , 2002, Cytokine & growth factor reviews.

[18]  Li Ni,et al.  Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion , 2002, Journal of neuroscience research.

[19]  M. Bracken.  Methylprednisolone and Acute Spinal Cord Injury: An Update of the Randomized Evidence , 2001, Spine.

[20]  Hurlbert Rj.  The role of steroids in acute spinal cord injury: an evidence-based analysis. , 2001 .

[21]  C. Hulsebosch,et al.  IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury. , 2001, Journal of neurotrauma.

[22]  J. Wrathall,et al.  Changes in NMDA Receptor Subunit Expression in Response to Contusive Spinal Cord Injury , 2000, Journal of neurochemistry.

[23]  B. Winblad,et al.  Increased expression of mRNA encoding interleukin‐1β and caspase‐1, and the secreted isoform of interleukin‐1 receptor antagonist in the rat brain following systemic kainic acid administration , 2000, Journal of neuroscience research.

[24]  S. Rogers,et al.  Inflammatory Cytokines IL-1α, IL-1β, IL-6, and TNF-α Impart Neuroprotection to an Excitotoxin Through Distinct Pathways , 1999, The Journal of Immunology.

[25]  D. McAdoo,et al.  Changes in Amino Acid Concentrations over Time and Space around an Impact Injury and Their Diffusion Through the Rat Spinal Cord , 1999, Experimental Neurology.

[26]  D. McAdoo,et al.  Neurotoxicity of glutamate at the concentration released upon spinal cord injury , 1999, Neuroscience.

[27]  N. Rothwell,et al.  Excitotoxic brain damage in the rat induces interleukin‐1β protein in microglia and astrocytes: Correlation with the progression of cell death , 1999, Glia.

[28]  N. Rothwell.  Cytokines ‐ killers in the brain? , 1999 .

[29]  N. Thornberry,et al.  Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors* , 1998, The Journal of Biological Chemistry.

[30]  P. V. Rayudu,et al.  Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation , 1998, Neuroscience.

[31]  D. McAdoo,et al.  Considerations in the determination by microdialysis of resting extracellular amino acid concentrations and release upon spinal cord injury , 1998, Neuroscience.

[32]  M. Schwab,et al.  Expression of Pro‐Inflammatory Cytokine and Chemokine mRNA Upon Experimental Spinal Cord Injury in Mouse: an In Situ Hybridization Study , 1997, The European journal of neuroscience.

[33]  N. Rothwell,et al.  Sixteenth Gaddum Memorial Lecture December 1996. Neuroimmune interactions: the role of cytokines , 1997, British journal of pharmacology.

[34]  J. Wrathall,et al.  Increase of interleukin-1β mRNA and protein in the spinal cord following experimental traumatic injury in the rat , 1997, Brain Research.

[35]  J. Wrathall,et al.  Delayed Antagonism of AMPA/Kainate Receptors Reduces Long-Term Functional Deficits Resulting from Spinal Cord Trauma , 1997, Experimental Neurology.

[36]  H. Winn,et al.  Administration of Methylprednisolone for 24 or 48 Hours or Tirilazad Mesylate for 48 Hours in the Treatment of Acute Spinal Cord Injury Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial , 1997 .

[37]  M. Fehlings,et al.  Role of NMDA and Non-NMDA Ionotropic Glutamate Receptors in Traumatic Spinal Cord Axonal Injury , 1997, The Journal of Neuroscience.

[38]  C. Plata-salamán,et al.  In Vivo Regulation of the IL-1β System (Ligand, Receptors I and II, Receptor Accessory Protein, and Receptor Antagonist) and TNF-α mRNAs in Specific Brain Regions , 1996 .

[39]  J. Zhou,et al.  [Changes of N-methyl-D-aspartate receptor in spinal cord after trauma]. , 1996, Zhonghua wai ke za zhi [Chinese journal of surgery].

[40]  J. Wrathall,et al.  Amelioration of Functional Deficits from Spinal Cord Trauma with Systemically Administered NBQX, an Antagonist of Non-N-methyl-D-aspartate receptors , 1996, Experimental Neurology.

[41]  K. Lees,et al.  Clinical experience with excitatory amino acid antagonist drugs. , 1995, Stroke.

[42]  D. Basso,et al.  A sensitive and reliable locomotor rating scale for open field testing in rats. , 1995, Journal of neurotrauma.

[43]  J. Wrathall,et al.  Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[44]  A. Mantovani,et al.  Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. , 1993, Science.

[45]  J. Olney,et al.  NMDA antagonist neurotoxicity: mechanism and prevention. , 1991, Science.

[46]  M. Bracken,et al.  The Second National Acute Spinal Cord Injury Study. , 1990, Journal of neurotrauma.

[47]  A. Faden,et al.  Alteration in extracellular amino acids after traumatic spinal cord injury , 1990, Annals of neurology.

[48]  B Henderson,et al.  Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[49]  T. Hökfelt,et al.  6-hydroxytryptamine--a new tool in monoamine fluorescence histochemistry. , 1969, Brain research.

[50]  C. Gabay,et al.  Interleukin-1 receptor antagonist: role in biology. , 1998, Annual review of immunology.

[51]  L. Noble,et al.  N-methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, and neurochemical studies. , 1988, Journal of neurotrauma.