Intracanalicular optic nerve meningioma: a serious diagnostic pitfall.

We describe six cases of cannalicular optic nerve meningioma in which the diagnosis was missed for more than 1 year after the onset of symptoms. Clinical features led to a misdiagnosis of optic neuritis in all cases. Although atypical clinical progression led to further imaging studies, they did not provide the diagnosis because of inappropriate imaging protocols. Diagnosis was eventually made on the basis of high-spatial-resolution contrast-enhanced MR findings. Radiologists should have a high suspicion for the diagnosis of optic canal meningioma in patients with unexplained visual loss, particularly when visual loss is progressive. Investigation in these cases should include high-spatial-resolution MR imaging of the orbit before and after contrast medium administration, and fat suppression should be used in combination with contrast enhancement whenever possible.

[1]  M. Vaphiades Disk edema and cranial MRI optic nerve enhancement: how long is too long? , 2001, Survey of ophthalmology.

[2]  J. Lee,et al.  Surgical Management of Clinoidal Meningiomas , 2001, Neurosurgery.

[3]  N. Tamaki,et al.  Treatment of tuberculum sellae meningiomas:a long-term follow-up study , 2001, Journal of Clinical Neuroscience.

[4]  J. Régis,et al.  Gamma knife radiosurgery in the management of cavernous sinus meningiomas. , 2000, Journal of neurosurgery.

[5]  T. Ohta,et al.  Surgical strategy for meningioma extension into the optic canal. , 2000, Neurologia medico-chirurgica.

[6]  R Miralbell,et al.  Optimizing radiotherapy of orbital and paraorbital tumors: intensity-modulated X-ray beams vs. intensity-modulated proton beams. , 2000, International journal of radiation oncology, biology, physics.

[7]  S. Nakano,et al.  Thresholds of ischemia salvageable with intravenous tissue plasminogen activator therapy: evaluation with cerebral blood flow single-photon emission computed tomographic measurements. , 2000, Neurosurgery.

[8]  K. Golnik,et al.  Treatment of optic nerve sheath meningioma with three-dimensional conformal radiation. , 2000, American journal of ophthalmology.

[9]  A. Jackson,et al.  Combined fat- and water-suppressed MR imaging of orbital tumors. , 1999, AJNR. American journal of neuroradiology.

[10]  H. Koga,et al.  An extensive cranial base meningioma extending bilaterally into Meckel's cave: case report. , 1997, Neurosurgery.

[11]  S. Schochet,et al.  Radiologic-pathologic correlation: meningioma of the optic nerve sheath. , 1996, AJNR. American journal of neuroradiology.

[12]  R. Delfini,et al.  Primary benign tumors of the orbital cavity: comparative data in a series of patients with optic nerve glioma, sheath meningioma, or neurinoma. , 1996, Surgical neurology.

[13]  J. Dutton Optic nerve sheath meningiomas. , 1992, Survey of ophthalmology.

[14]  J. B. Kneeland,et al.  MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique. , 1990, AJNR. American journal of neuroradiology.

[15]  W. T. Shults,et al.  Combined clinical and computed tomographic diagnosis of orbital glioma and meningioma. , 1984, Ophthalmology.

[16]  J. L. Smith,et al.  Fluorescein angiography of optociliary shunt vessels. , 1981, Journal of clinical neuro-ophthalmology.

[17]  P. De Potter,et al.  Optic nerve sheath meningiomas: clinical features, functional prognosis and controversial treatment. , 2000, Bulletin de la Societe belge d'ophtalmologie.

[18]  M. Mafee,et al.  OPTIC NERVE SHEATH MENINGIOMAS: Role of MR Imaging , 1999 .

[19]  A. Jackson,et al.  Optic neuritis: MR imaging with combined fat- and water-suppression techniques. , 1998, Radiology.

[20]  J. Hodes,et al.  Radiosurgical management of meningiomas. , 1996, Stereotactic and functional neurosurgery.

[21]  E. Markakis,et al.  Symptomatology, surgical therapy and postoperative results of sphenoorbital, intraorbital-intracanalicular and optic sheath meningiomas. , 1996, Acta neurochirurgica. Supplement.

[22]  J. B. Kneeland,et al.  MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique. , 1990, AJR. American journal of roentgenology.