Hypovitaminosis D and pain in cystic fibrosis.

To the Editor, Cystic fibrosis (CF) is the most common life-shortening genetic disease in whites. It principally affects the lungs, pancreas and gastrointestinal tract [1]. Advances in the treatment have improved the life expectancy of people with CF [2]. The increased longevity of adults with CF is accompanied by a rising prevalence of secondary complications including pain [3], which can be associated with the diagnosis and treatment of the disease, and the disease itself [4]. A recent study [5] found that 82% of patients reported pain within the past month, the most common sites being the head, sinuses, back, and chest. Pain frequently interfered with general activities (41.9%), mood (56.8%), and work (47.3%). Symptoms of depression and anxiety, as well as lower quality-of-life scores, were associated …

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