Visualizing microtubule structural transitions and interactions with associated proteins.

[1]  Eva Nogales,et al.  A new protocol to accurately determine microtubule lattice seam location. , 2015, Journal of structural biology.

[2]  E. Nogales,et al.  Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins , 2015, Cell.

[3]  G. Lander,et al.  Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases , 2015, Cell.

[4]  N. Hirokawa,et al.  X‐ray and Cryo‐EM structures reveal mutual conformational changes of Kinesin and GTP‐state microtubules upon binding , 2015, The EMBO journal.

[5]  Kai Zhang,et al.  The structure of the dynactin complex and its interaction with dynein , 2015, Science.

[6]  T. Schroer,et al.  Structural organization of the dynein-dynactin complex bound to microtubules , 2015, Nature Structural &Molecular Biology.

[7]  Chen Xu,et al.  High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation , 2014, eLife.

[8]  L. Rice,et al.  JCB_201407095 1..12 , 2014 .

[9]  Maya Topf,et al.  Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins , 2014, eLife.

[10]  Carsten Janke,et al.  The tubulin code: Molecular components, readout mechanisms, and functions , 2014, The Journal of cell biology.

[11]  Á. Crevenna,et al.  Structural basis for the extended CAP-Gly domains of p150glued binding to microtubules and the implication for tubulin dynamics , 2014, Proceedings of the National Academy of Sciences.

[12]  N. Grigorieff,et al.  Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase , 2014, Cell.

[13]  D. Baker,et al.  High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis , 2014, Cell.

[14]  R. Vale,et al.  Regulation of microtubule motors by tubulin isotypes and posttranslational modifications , 2014, Nature Cell Biology.

[15]  Gergő Bohner,et al.  EB1 Accelerates Two Conformational Transitions Important for Microtubule Maturation and Dynamics , 2014, Current Biology.

[16]  Steven P Gross,et al.  Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family , 2014, Proceedings of the National Academy of Sciences.

[17]  S. Burgess,et al.  Functions and mechanics of dynein motor proteins , 2013, Nature Reviews Molecular Cell Biology.

[18]  David Baker,et al.  High-resolution comparative modeling with RosettaCM. , 2013, Structure.

[19]  M. Steinmetz,et al.  Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents , 2013, Science.

[20]  Samara L. Reck-Peterson,et al.  Structural Basis for Microtubule Binding and Release by Dynein , 2012, Science.

[21]  E. Nogales,et al.  Multi-modal microtubule binding by the Ndc80 kinetochore complex , 2012, Nature Structural &Molecular Biology.

[22]  L. Rice,et al.  A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase , 2012, Science.

[23]  Gergő Bohner,et al.  EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends , 2012, Cell.

[24]  A. Hoenger,et al.  GTPγS microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs) , 2011, Proceedings of the National Academy of Sciences.

[25]  D. Clare,et al.  Template-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolution , 2010, The Journal of cell biology.

[26]  C. Dumontet,et al.  Microtubule-binding agents: a dynamic field of cancer therapeutics , 2010, Nature Reviews Drug Discovery.

[27]  E. Nogales,et al.  The Ndc80 kinetochore complex forms oligomeric arrays along microtubules , 2010, Nature.

[28]  Niels Galjart,et al.  Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends , 2010, Current Biology.

[29]  Arne Gennerich,et al.  Walking the walk: how kinesin and dynein coordinate their steps. , 2009, Current opinion in cell biology.

[30]  Anna Akhmanova,et al.  Tracking the ends: a dynamic protein network controls the fate of microtubule tips , 2008, Nature Reviews Molecular Cell Biology.

[31]  R. Vale,et al.  Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. , 2007, Molecular cell.

[32]  Kenneth H. Downing,et al.  The beginning of kinesin's force-generating cycle visualized at 9-Å resolution , 2007, The Journal of cell biology.

[33]  Edward H Egelman,et al.  The iterative helical real space reconstruction method: surmounting the problems posed by real polymers. , 2007, Journal of structural biology.

[34]  Samara L. Reck-Peterson,et al.  The Affinity of the Dynein Microtubule-binding Domain Is Modulated by the Conformation of Its Coiled-coil Stalk*[boxs] , 2005, Journal of Biological Chemistry.

[35]  M. Ikura,et al.  Crystal Structure of the Amino-terminal Microtubule-binding Domain of End-binding Protein 1 (EB1)* , 2003, Journal of Biological Chemistry.

[36]  William V Nicholson,et al.  Microtubule structure at 8 A resolution. , 2002, Structure.

[37]  E. Nogales,et al.  Refined structure of alpha beta-tubulin at 3.5 A resolution. , 2001, Journal of molecular biology.

[38]  P. Curmi,et al.  The 4 Å X-Ray Structure of a Tubulin:Stathmin-like Domain Complex , 2000, Cell.

[39]  E. Nogales,et al.  High-Resolution Model of the Microtubule , 1999, Cell.

[40]  E. Nogales,et al.  Tubulin and FtsZ form a distinct family of GTPases , 1998, Nature Structural Biology.

[41]  E. Nogales,et al.  Structure of the alpha beta tubulin dimer by electron crystallography. , 1998, Nature.

[42]  A. Hyman,et al.  Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP. , 1992, Molecular biology of the cell.

[43]  D. Hackney,et al.  Kinesin ATPase: rate-limiting ADP release. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[44]  E. Mandelkow,et al.  On the surface lattice of microtubules: helix starts, protofilament number, seam, and handedness , 1986, The Journal of cell biology.

[45]  M. Kirschner,et al.  Dynamic instability of microtubule growth , 1984, Nature.