Synthetic glycopolymers as modulators of protein aggregation: influences of chemical composition, topology and concentration.
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S. Allen | G. Mantovani | S. Stolnik | J Madeira do O | F Mastrotto | N Francini | S Allen | C F van der Walle | S Stolnik | G Mantovani | F. Mastrotto | Nora Francini | C. F. Walle | Ó. JoãoMadeirado
[1] V. Bhakta,et al. Prolonged in vivo anticoagulant activity of a hirudin–albumin fusion protein secreted from Pichia pastoris , 2001, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
[2] A Detailed Study on Understanding Glycopolymer Library and Con A Interactions , 2013, Journal of polymer science. Part A, Polymer chemistry.
[3] Lei Tao,et al. A Modular Click Approach to Glycosylated Polymeric Beads: Design, Synthesis and Preliminary Lectin Recognition Studies , 2007 .
[4] Daniel E. Otzen,et al. Protein drug stability: a formulation challenge , 2005, Nature Reviews Drug Discovery.
[5] R. Langer,et al. Formulation and delivery of proteins and peptides , 1994 .
[6] J. Coloma,et al. Removal of amphipathic epitopes from genetically engineered antibodies: production of modified immunoglobulins with reduced immunogenicity. , 2000, Hybridoma.
[7] John F. Carpenter,et al. Physical Stability of Proteins in Aqueous Solution: Mechanism and Driving Forces in Nonnative Protein Aggregation , 2003, Pharmaceutical Research.
[8] Wim Jiskoot,et al. Extrinsic Fluorescent Dyes as Tools for Protein Characterization , 2008, Pharmaceutical Research.
[9] Paul A Dalby,et al. Mapping the Aggregation Kinetics of a Therapeutic Antibody Fragment. , 2016, Molecular pharmaceutics.
[10] Steven J. Shire,et al. The Effect of Formulation Excipients on Protein Stability and Aerosol Performance of Spray-Dried Powders of a Recombinant Humanized Anti-IgE Monoclonal Antibody1 , 1999, Pharmaceutical Research.
[11] A. Fink,et al. Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins. , 2007, Biochimica et biophysica acta.
[12] S. N. Timasheff,et al. Mechanism of the stabilization of ribonuclease a by sorbitol: Preferential hydration is greater for the denatured than for the native protein , 1997, Protein science : a publication of the Protein Society.
[13] N. Warne,et al. Development of high concentration protein biopharmaceuticals: the use of platform approaches in formulation development. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[14] R T Borchardt,et al. Inhibitory effect of sugars and polyols on the metal-catalyzed oxidation of human relaxin. , 1996, Journal of pharmaceutical sciences.
[15] V. Ladmiral,et al. Synthesis of neoglycopolymers by a combination of "click chemistry" and living radical polymerization. , 2006, Journal of the American Chemical Society.
[16] M. Roberts,et al. Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies , 2009, AAPS PharmSciTech.
[17] Wei Wang,et al. Protein aggregation and its inhibition in biopharmaceutics. , 2005, International journal of pharmaceutics.
[18] D. Ecker,et al. The therapeutic monoclonal antibody market , 2015, mAbs.
[19] I. Roy,et al. Effect of trehalose on protein structure , 2008, Protein science : a publication of the Protein Society.
[20] R. Bhat,et al. Thermal Stability of Proteins in Aqueous Polyol Solutions: Role of the Surface Tension of Water in the Stabilizing Effect of Polyols , 1998 .
[21] C Russell Middaugh,et al. Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry. , 2013, Journal of pharmaceutical sciences.
[22] Satoshi Ohtake,et al. Interactions of formulation excipients with proteins in solution and in the dried state. , 2011, Advanced drug delivery reviews.
[23] Y. Miura,et al. A specific inhibitory effect of multivalent trehalose toward Aβ(1-40) aggregation , 2011 .
[24] D. P. Santana,et al. Application of thermal analysis in study of binary mixtures with metformin , 2008 .
[25] Wolfgang Friess,et al. Temperature-ramped studies on the aggregation, unfolding, and interaction of a therapeutic monoclonal antibody. , 2014, Journal of pharmaceutical sciences.
[26] Alexander F. Christiansen,et al. Effects of macromolecular crowding agents on protein folding in vitro and in silico , 2013, Biophysical Reviews.
[27] Massimo Morbidelli,et al. Effect of polyol sugars on the stabilization of monoclonal antibodies. , 2015, Biophysical chemistry.
[28] H. Maynard,et al. Trehalose glycopolymers for stabilization of protein conjugates to environmental stressors. , 2012, Journal of the American Chemical Society.
[29] Malgorzata B. Tracka,et al. The effect of arginine glutamate on the stability of monoclonal antibodies in solution , 2014, International journal of pharmaceutics.
[30] F. Davis,et al. Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. , 1977, The Journal of biological chemistry.
[31] Steven Lantz,et al. Examination of thermal unfolding and aggregation profiles of a series of developable therapeutic monoclonal antibodies. , 2015, Molecular pharmaceutics.
[32] R. Wallis,et al. High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein , 2010, Journal of the American Chemical Society.
[33] Kouhei Tsumoto,et al. Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress , 2013, Protein science : a publication of the Protein Society.
[34] R. Bhat,et al. Why Is Trehalose an Exceptional Protein Stabilizer? , 2003, Journal of Biological Chemistry.
[35] C. R. Becer,et al. Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin , 2016 .
[36] Gaojian Chen,et al. Synthesis of thermo-responsive glycopolymersviacopper catalysed azide–alkyne ‘click’ chemistry for inhibition of ricin: the effect of spacer between polymer backbone and galactose , 2011 .
[37] En-Wei Lin,et al. Trehalose glycopolymers as excipients for protein stabilization. , 2013, Biomacromolecules.
[38] Tim J Kamerzell,et al. Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development. , 2011, Advanced drug delivery reviews.
[39] Aditi Sharma,et al. Gauging colloidal and thermal stability in human IgG1-sugar solutions through diffusivity measurements. , 2014, The journal of physical chemistry. B.
[40] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[41] Deborah S. Goldberg,et al. Formulation development of therapeutic monoclonal antibodies using high-throughput fluorescence and static light scattering techniques: role of conformational and colloidal stability. , 2011, Journal of pharmaceutical sciences.
[42] Thomas W. Patapoff,et al. Opposite Effects of Polyols on Antibody Aggregation: Thermal Versus Mechanical Stresses , 2011, Pharmaceutical Research.
[43] J. Geng,et al. Well‐Defined Poly(N‐glycosyl 1,2,3‐triazole) Multivalent Ligands: Design, Synthesis and Lectin Binding Studies , 2007 .
[44] W Wang,et al. Instability, stabilization, and formulation of liquid protein pharmaceuticals. , 1999, International journal of pharmaceutics.
[45] M. Al-omari,et al. Amlodipine Besylate–Excipients Interaction in Solid Dosage Form , 2004, Pharmaceutical development and technology.
[46] P. Caliceti,et al. Therapeutic proteins: a comparison of chemical and biological properties of uricase conjugated to linear or branched poly(ethylene glycol) and poly(N-acryloylmorpholine). , 2000, Farmaco.
[47] P. Corran,et al. Lysine vasopressin undergoes rapid glycation in the presence of reducing sugars. , 1994, Journal of pharmaceutical and biomedical analysis.
[48] Lei Tao,et al. Synthesis of semitelechelic maleimide poly(PEGA) for protein conjugation by RAFT polymerization. , 2009, Biomacromolecules.
[49] P. Nordlund,et al. Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination , 2006, Proceedings of the National Academy of Sciences.
[50] S. Evans,et al. Site-directed conjugation of "clicked" glycopolymers to form glycoprotein mimics: binding to mammalian lectin and induction of immunological function. , 2007, Journal of the American Chemical Society.
[51] Slowing down of water dynamics in disaccharide aqueous solutions , 2010, 1005.5327.
[52] Peter York,et al. A Central Composite Design to Investigate the Thermal Stabilization of Lysozyme , 1999, Pharmaceutical Research.
[53] Christoffer Olsson,et al. The Role of Trehalose for the Stabilization of Proteins. , 2016, The journal of physical chemistry. B.
[54] Kevin Barraclough,et al. I and i , 2001, BMJ : British Medical Journal.
[55] J. Lee,et al. The stabilization of proteins by sucrose. , 1981, The Journal of biological chemistry.