Rhabdomyolysis following cardiopulmonary bypass and treatment with enoximone in a patient susceptible to malignant hyperthermia.

SEVERE hypercapnia, muscle rigidity, hyperthermia, and rhabdomyolysis characterize malignant hyperthermia (MH) in fulminant form. However, during cardiac operations using cardiopulmonary bypass (CPB), typical symptoms of MH may not be present. We observed a patient undergoing aortic valve replacement, in whom severe postoperative rhabdomyolysis and arrhythmias developed after treatment with enoximone during CPB and cardioplegic arrest. Subsequently, in vitro contracture testing showed that the patient was susceptible to MH.

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