Correlation of lactose maldigestion, lactose intolerance, and milk intolerance.

Lactose digestion and tolerance were evaluated in 164 African Americans ranging in age from 12 to 40 y who claimed intolerance to one cup (240 mL) or less of milk. With use of a breath-hydrogen test with 25 g lactose as test dose and the presence or absence of symptoms, 50% of the subjects were classified as lactose maldigesters and intolerant, 8% were maldigesters but tolerant, 15% were digesters but intolerant, and 27% were digesters and tolerant. Forty-five subjects from the lactose maldigesting and intolerant group were further tested for milk intolerance in a double-blind study. Sixty-seven percent of the subjects reacted appropriately to the presence or absence of lactose in ingested milk whereas 33% reported symptoms to both low-lactose milk and milk containing lactose. The results suggest that the cause of milk intolerance in as many as one-third of African Americans claiming symptoms after ingestion of a moderate amount of milk cannot be its lactose content.

[1]  L. Allen,et al.  Milk consumption, symptom response, and lactose digestion in milk intolerance. , 1987, The American journal of clinical nutrition.

[2]  Y. Joshi,et al.  Lactose intolerance in North and South Indians. , 1981, The American journal of clinical nutrition.

[3]  N. Scrimshaw,et al.  Comparative tolerance of adolescents of differing ethnic backgrounds to lactose-containing and lactose-free dairy drinks. II. Improvement of a double-blind test. , 1980, The American journal of clinical nutrition.

[4]  N. Scrimshaw,et al.  Comparative tolerance of elderly from differing ethnic backgrounds to lactose-containing and lactose-free dairy drinks: a double-blind study. , 1979, Journal of gerontology.

[5]  Y. Lacassie,et al.  Poor predictability of lactose malabsorption from clinical symptoms for Chilean populations. , 1978, The American journal of clinical nutrition.

[6]  H. Gordon,et al.  Family studies of lactase deficiency in the American Indian. , 1977, Gastroenterology.

[7]  C. Woteki,et al.  Lactose malabsorption in Mexican-American adults. , 1977, The American journal of clinical nutrition.

[8]  N. Scrimshaw,et al.  Relationship of lactose intolerance to milk intolerance in young children. , 1976, The American journal of clinical nutrition.

[9]  L. Stephenson,et al.  Lactose intolerance and milk consumption: the relation of tolerance to symptoms. , 1974, The American journal of clinical nutrition.

[10]  F. Simoons.  The Determinants of Dairying and Milk Use in the Old World: Ecological, Physiological, and Cultural , 2018, Food, Ecology and Culture.

[11]  N. Kretchmer.  Lactose and lactase--a historical perspective. , 1971, Gastroenterology.

[12]  J. Welsh,et al.  Studies of Lactose Intolerance in Families , 1968 .

[13]  T. Bayless,et al.  Milk and Lactose Intolerance in Healthy Orientals , 1968, Science.

[14]  A. Dawson,et al.  Jejunal disaccharidases and some observations on the cause of lactase deficiency. , 1966, British medical journal.

[15]  P. Cuatrecasas,et al.  LACTASE DEFICIENCY IN THE ADULT , 1965 .

[16]  P. Cuatrecasas,et al.  LACTASE DEFICIENCY IN THE ADULT. A COMMON OCCURRENCE. , 1965, Lancet.