Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR).
暂无分享,去创建一个
Stephen G Swisher | Jack A Roth | Kelly K Hunt | K. Hunt | J. Roth | S. Swisher | A. Mhashilkar | S. Chada | G. Barber | S. Balachandran | A. Pataer | Abujiang Pataer | Stephan A Vorburger | Glen N Barber | Sunil Chada | Abner M Mhashilkar | Helena Zou-Yang | Alexis L Stewart | Siddharth Balachandran | S. Vorburger | Alexis L. Stewart | Helena Zou-Yang | Siddharth Balachandran
[1] K. Hunt,et al. Adenoviral Bak overexpression mediates caspase-dependent tumor killing. , 2000, Cancer research.
[2] G. Barber,et al. PKR, apoptosis and cancer. , 1999, The international journal of biochemistry & cell biology.
[3] S. Hanash,et al. Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias. , 1996, Oncogene.
[4] R. Silverman,et al. RNA-Dependent Protein Kinase PKR Is Required for Activation of NF-κB by IFN-γ in a STAT1-Independent Pathway1 , 2001, The Journal of Immunology.
[5] J. Roth,et al. Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro , 2000, Gene Therapy.
[6] S. Der,et al. A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[7] R. Jagus,et al. Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[8] B. Williams,et al. The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin , 2000, The EMBO journal.
[9] P. Roberts,et al. Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection. , 2000, Immunity.
[10] A. Cuddihy,et al. Double-Stranded-RNA-Activated Protein Kinase PKR Enhances Transcriptional Activation by Tumor Suppressor p53 , 1999, Molecular and Cellular Biology.
[11] R. Wek,et al. Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2). , 2001, European journal of biochemistry.
[12] F. Khuri,et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. , 1999, Journal of the National Cancer Institute.
[13] A. Hinnebusch,et al. Binding of Double-stranded RNA to Protein Kinase PKR Is Required for Dimerization and Promotes Critical Autophosphorylation Events in the Activation Loop* , 2001, The Journal of Biological Chemistry.
[14] D. Lejeune,et al. Cutting Edge: STAT Activation By IL-19, IL-20 and mda-7 Through IL-20 Receptor Complexes of Two Types1 , 2001, The Journal of Immunology.
[15] D. Green,et al. Apoptosis and cancer. , 1994, Important advances in oncology.
[16] S. Hasnain,et al. Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B. , 2000, Biochemistry.
[17] M. Esteban,et al. Induction of Apoptosis by Double-Stranded-RNA-Dependent Protein Kinase (PKR) Involves the α Subunit of Eukaryotic Translation Initiation Factor 2 and NF-κB , 1999, Molecular and Cellular Biology.
[18] Z. Su,et al. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. , 1995, Oncogene.
[19] Peter Vandenabeele,et al. Translation Inhibition in Apoptosis , 2001, The Journal of Biological Chemistry.
[20] H. Tsutsumi. [Viral infection]. , 2002, Nihon rinsho. Japanese journal of clinical medicine.
[21] Z. Su,et al. The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[22] T. Mak,et al. Activation of the dsRNA‐dependent protein kinase, PKR, induces apoptosis through FADD‐mediated death signaling , 1998, The EMBO journal.
[23] G. Ghadge,et al. Expression of the protein kinase p-68 recognized by the monoclonal antibody TJ4C4 in human lung neoplasms , 1992, Virchows Archiv. B, Cell pathology including molecular pathology.