Host Range Restriction and Pathogenicity in the Context of Influenza Pandemic

Certain viral factors determine the host range restriction and pathogenicity of influenza A viruses.

[1]  Y. Guan,et al.  Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia , 2004, Nature.

[2]  B. Murphy,et al.  The avian influenza virus nucleoprotein gene and a specific constellation of avian and human virus polymerase genes each specify attenuation of avian-human influenza A/Pintail/79 reassortant viruses for monkeys , 1987, Journal of virology.

[3]  R. Webster,et al.  Lethal H5N1 influenza viruses escape host anti-viral cytokine responses , 2002, Nature Medicine.

[4]  I. Wilson,et al.  Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity , 1983, Nature.

[5]  Yoshihiro Kawaoka,et al.  Early Alterations of the Receptor-Binding Properties of H1, H2, and H3 Avian Influenza Virus Hemagglutinins after Their Introduction into Mammals , 2000, Journal of Virology.

[6]  R. Webster,et al.  Potential for transmission of avian influenza viruses to pigs. , 1994, The Journal of general virology.

[7]  J. Farrar,et al.  Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. , 2005, The New England journal of medicine.

[8]  B. Murphy,et al.  A single amino acid in the PB2 gene of influenza A virus is a determinant of host range , 1993, Journal of virology.

[9]  R. Krug,et al.  Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein. , 2003, Virology.

[10]  Yoshihiro Kawaoka,et al.  Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential , 1998, Journal of Virology.

[11]  J. Paulson,et al.  Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin. , 1983, Virology.

[12]  R. Webster,et al.  Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus , 1998, The Lancet.

[13]  Maricarmen García,et al.  Heterogeneity in the haemagglutinin gene and emergence of the highly pathogenic phenotype among recent H5N2 avian influenza viruses from Mexico. , 1996, The Journal of general virology.

[14]  W G Laver,et al.  An 18-amino acid deletion in an influenza neuraminidase. , 1985, Virology.

[15]  G. Air,et al.  Variation in the membrane-insertion and "stalk" sequences in eight subtypes of influenza type A virus neuraminidase. , 1982, Biochemistry.

[16]  H. Goto,et al.  Biological Heterogeneity, Including Systemic Replication in Mice, of H5N1 Influenza A Virus Isolates from Humans in Hong Kong , 1999, Journal of Virology.

[17]  I. Capua,et al.  Changes in the haemagglutinin and the neuraminidase genes prior to the emergence of highly pathogenic H7N1 avian influenza viruses in Italy , 2001, Archives of Virology.

[18]  R. Webster,et al.  Avian-to-human transmission of the PB1 gene of influenza A viruses in the 1957 and 1968 pandemics , 1989, Journal of virology.

[19]  A. García-Sastre.  Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses. , 2004, Current topics in microbiology and immunology.

[20]  P. Massin,et al.  Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses. , 2000, The Journal of general virology.

[21]  R. Webster,et al.  Cooperation between the Hemagglutinin of Avian Viruses and the Matrix Protein of Human Influenza A Viruses , 2002, Journal of Virology.

[22]  C. Scholtissek,et al.  On the origin of the human influenza virus subtypes H2N2 and H3N2. , 1978, Virology.

[23]  T. Kuiken,et al.  Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[24]  H. Klenk,et al.  Human and avian influenza viruses target different cell types in cultures of human airway epithelium. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[25]  J. Paulson,et al.  The N2 neuraminidase of human influenza virus has acquired a substrate specificity complementary to the hemagglutinin receptor specificity. , 1991, Virology.

[26]  R. Webster,et al.  H5N1 influenza: a protean pandemic threat. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. Paulson,et al.  Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity. , 1993, Virus research.

[28]  D. J. Stevens,et al.  The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin , 2004, Science.

[29]  Yoshihiro Kawaoka,et al.  Amino Acid Residues Contributing to the Substrate Specificity of the Influenza A Virus Neuraminidase , 1999, Journal of Virology.

[30]  Prasert Auewarakul,et al.  Molecular characterization of the complete genome of human influenza H5N1 virus isolates from Thailand. , 2005, The Journal of general virology.

[31]  R. Webster,et al.  The Surface Glycoproteins of H5 Influenza Viruses Isolated from Humans, Chickens, and Wild Aquatic Birds Have Distinguishable Properties , 1999, Journal of Virology.

[32]  Roger E Bumgarner,et al.  Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[33]  Yoshihiro Kawaoka,et al.  Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses , 2001, Science.

[34]  Hidekazu Nishimura,et al.  Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus , 2004, Nature.

[35]  N. Cox,et al.  A Mouse Model for the Evaluation of Pathogenesis and Immunity to Influenza A (H5N1) Viruses Isolated from Humans , 1999, Journal of Virology.

[36]  Y. Guan,et al.  Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? , 2002, The Lancet.

[37]  Ian A. Wilson,et al.  Structure of the Uncleaved Human H1 Hemagglutinin from the Extinct 1918 Influenza Virus , 2004, Science.

[38]  Marion Koopmans,et al.  Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[39]  M. Katze,et al.  Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus , 2004, Journal of Virology.

[40]  N. Cox,et al.  Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. , 1998, Science.

[41]  R. Webster,et al.  The NS1 gene of H5N1 influenza viruses circumvents the host anti-viral cytokine responses. , 2004, Virus research.

[42]  H. Klenk,et al.  Understanding influenza virus pathogenicity. , 1999, Trends in microbiology.

[43]  J. Pasick,et al.  Intersegmental recombination between the haemagglutinin and matrix genes was responsible for the emergence of a highly pathogenic H7N3 avian influenza virus in British Columbia. , 2005, The Journal of general virology.

[44]  R. Webster,et al.  H9N2 influenza A viruses from poultry in Asia have human virus-like receptor specificity. , 2001, Virology.

[45]  P. Palese,et al.  Alterations of the stalk of the influenza virus neuraminidase: deletions and insertions. , 1993, Virus research.

[46]  D. Miyamoto,et al.  Duck and human pandemic influenza A viruses retain sialidase activity under low pH conditions. , 2001, Journal of biochemistry.

[47]  C. Naeve,et al.  Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin? , 1984, Virology.

[48]  I. Brown,et al.  Recombination Resulting in Virulence Shift in Avian Influenza Outbreak, Chile , 2004, Emerging infectious diseases.

[49]  Y. Kawaoka,et al.  Reverse genetics provides direct evidence for a correlation of hemagglutinin cleavability and virulence of an avian influenza A virus , 1994, Journal of virology.