论文信息 - A continuing focus of yellow fever in the Apurimac River Valley, Ayacucho, Peru, and the first isolation of yellow fever virus in that country.

A continuing focus of yellow fever in the Apurimac River Valley, Ayacucho, Peru, and the first isolation of yellow fever virus in that country.

Clinical sylvatic yellow fever (YF) in Peru may have been reported as early as 1913 by Rojas (I); however, the earliest known outbreak that has been reported was that cited by Giles and Pinto (2) as occurring in Chanchamayo (Junin Department) in 1925. It has also been shown that children living along the upper Amazon River in Brazil and Peru during 1931 had antibody to YF virus (3); and serologic surveys for antibody to YF virus in 19331934 in thesame general area indicated that the antibody prevalence increased with age10.6% of the study subjects under 15 years old being found with antibody to YF virus, as compared to 50.2 % of those 15 years and older (4). That this immunity was not due to infec-

[1] A. T. D. Travassos da Rosa,et al. An epidemic of yellow fever in Central Brazil, 1972-1973. II. Ecological studies. , 1981, The American journal of tropical medicine and hygiene.

[2] J. Madalengoitia,et al. Study of VE virus and isolation of SLE, EE, group C, and GUAMA group arboviruses in the Amazon region of Peru, 1975. , 1979, Bulletin of the Pan American Health Organization.

[3] C. Calisher,et al. Serum dilution neutralization test for California group virus identification and serology , 1976, Journal of clinical microbiology.

[4] C. Leake,et al. Isolations in a mosquito (Aedes pseudoscutellaris) cell line (Mos. 61) of yellow fever virus strains from original field material. , 1975, Intervirology.