Integrative biology: real science through e-Science

‘eScience can be described as the large scale science that will increasingly be carried out through distributed global collaborations enabled by the Internet.’ This describes the fundamental requirements of the Integrative Biology project to support a diverse user community to bring together scientists and technologists to develop a ‘collaboratory’ for heart and cancer modelling. This paper aims to describe the scientific progress being made through the use of the facilities developed or made available to collaborating scientists in the area of complex heart modelling and describes how this new approach is changing the way that they perform their research.