Keratinocyte growth factor regulates proliferation and differentiation of hematopoietic cells expressing the receptor gene K-sam.

[1]  I. Touw,et al.  Multiple Signals Mediate Proliferation, Differentiation, and Survival from the Granulocyte Colony-stimulating Factor Receptor in Myeloid 32D Cells* , 1999, The Journal of Biological Chemistry.

[2]  Y. Ikawa,et al.  Self‐renewal and differentiation of a basic fibroblast growth factor‐dependent multipotent hematopoietic cell line derived from embryonic stem cells , 1999, Development, growth & differentiation.

[3]  Xinmin Cao,et al.  Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK) , 1998, Oncogene.

[4]  L. Ivashkiv,et al.  Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[5]  T. Hirano,et al.  Involvement of STAT3 in the Granulocyte Colony-stimulating Factor-induced Differentiation of Myeloid Cells* , 1997, The Journal of Biological Chemistry.

[6]  S. Goueli,et al.  Sustained Activation of the Extracellular Signal-regulated Kinase/Mitogen-activated Protein Kinase Pathway Is Required for Megakaryocytic Differentiation of K562 Cells* , 1997, The Journal of Biological Chemistry.

[7]  M. Uchida,et al.  In vitro development of erythroid and megakaryocytic cells from a UT-7 subline, UT-7/GM. , 1997, Blood.

[8]  N. Ahn,et al.  Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase , 1997, Molecular and cellular biology.

[9]  S. Hirohashi,et al.  Immunohistochemical detection of K-sam protein in stomach cancer. , 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

[10]  T. Ochiya,et al.  HST-1/FGF-4 stimulates proliferation of megakaryocyte progenitors synergistically and promotes megakaryocyte maturation. , 1996, Oncogene.

[11]  E. Fuchs,et al.  Keratinocyte growth factor is required for hair development but not for wound healing. , 1996, Genes & development.

[12]  H. Ishii,et al.  A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiation , 1995, Molecular and cellular biology.

[13]  D. Ron,et al.  Differential effect of cell-associated heparan sulfates on the binding of keratinocyte growth factor (KGF) and acidic fibroblast growth factor to the KGF receptor. , 1994, The Journal of biological chemistry.

[14]  T. Ochiya,et al.  Adenovirus-mediated transfer of the HST-1 (FGF4) gene induces increased levels of platelet count in vivo. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[15]  H. Ishii,et al.  Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity. , 1994, Cancer research.

[16]  H. Ishii,et al.  Preferential expression of the third immunoglobulin-like domain of K-sam product provides keratinocyte growth factor-dependent growth in carcinoma cell lines. , 1994, Cancer research.

[17]  Y. Yazaki,et al.  c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. , 1993, Biochemical and biophysical research communications.

[18]  J. Rubin,et al.  Expression of biologically active recombinant keratinocyte growth factor. Structure/function analysis of amino-terminal truncation mutants. , 1993, The Journal of biological chemistry.

[19]  T. Sugimura,et al.  K-sam-related gene, N-sam, encodes fibroblast growth factor receptor and is expressed in T-lymphocytic tumors. , 1992, Cancer research.

[20]  M. Li,et al.  FDC-P1 myeloid cells engineered to express fibroblast growth factor receptor 1 proliferate and differentiate in the presence of fibroblast growth factor and heparin. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[21]  Y. Yazaki,et al.  K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[22]  T. Sugimura,et al.  Expression of the heparin-binding growth factor receptor genes in human megakaryocytic leukemia cells. , 1992, Biochemical and biophysical research communications.

[23]  B. Olwin,et al.  Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation , 1991, Science.

[24]  Jeffrey D. Esko,et al.  Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor , 1991, Cell.

[25]  J. Rubin,et al.  Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. , 1991, Science.

[26]  Teruhiko Yoshida,et al.  K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. Yokota,et al.  Isolation of an Amplified DNA Sequence in Stomach Cancer , 1990, Japanese journal of cancer research : Gann.

[28]  J. Rubin,et al.  Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. , 1989, Science.

[29]  J. Rubin,et al.  Purification and characterization of a newly identified growth factor specific for epithelial cells. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[30]  E. Wimmer,et al.  A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation , 1988, Journal of virology.

[31]  D. Tweardy,et al.  Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line. , 1987, Journal of immunology.

[32]  H. Sakamoto,et al.  Detection of amplified DNA sequences in gastric cancers by a DNA renaturation method in gel. , 1986, Japanese journal of cancer research : Gann.

[33]  B. Olwin,et al.  Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts. , 1986, Biochemistry.

[34]  E. Olson,et al.  Control by fibroblast growth factor of differentiation in the BC3H1 muscle cell line , 1985, The Journal of cell biology.

[35]  J. Rubin,et al.  Keratinocyte growth factor as a cytokine that mediates mesenchymal-epithelial interaction. , 1995, EXS.

[36]  T. Fleming,et al.  Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. , 1992, Proceedings of the National Academy of Sciences of the United States of America.