The Herbal Medicine Unkei‐to Stimulates the Secretion of a Cytokine‐induced Neutrophil Chemoattractant, CINC/gro, in the Rat Ovarian Cell Culture

Yasui T, Matsuzaki T, Ogata R, Kiyokawa M, Ushigoe K, Uemura H, Kuwahara A, Ikawa H, Maegawa M, Furumoto H, Aono T, Irahara M. The herbal medicine Unkei‐to stimulates the secretion of a cytokine‐induced neutrophil chemoattractant, CINC/gro, in the rat ovarian cell culture. AJRI 2003; 49:–© Blackwell Munksgaard, 2003

[1]  T. Ushiroyama,et al.  Effects of unkei-to, an herbal medicine, on endocrine function and ovulation in women with high basal levels of luteinizing hormone secretion. , 2001, The Journal of reproductive medicine.

[2]  M. Irahara,et al.  Evidence that Toki-shakuyaku-san and its ingredients enhance the secretion of a cytokine-induced neutrophil chemoattractant (CINC/gro) in the ovulatory process. , 2000, Methods and findings in experimental and clinical pharmacology.

[3]  S. Kōzuma,et al.  Theoretical Basis for Herbal Medicines, Tokishakuyaku‐San and Sairei‐To, in the Treatment of Autoimmunity‐Related Recurrent Abortion by Correcting T Helper‐1/T Helper‐2 Balance , 2000, American journal of reproductive immunology.

[4]  M. Irahara,et al.  Production and Regulation of Cytokine-Induced Neutrophil Chemoattractant in Rat Ovulation , 2000, Biology of reproduction.

[5]  S. Kōzuma,et al.  Effects of sairei-to and tokishakuyaku-san on cytokine release from peripheral blood mononuclear cells upon recognition of HLA-G protein in the treatment of recurrent abortion. , 1999, Methods and findings in experimental and clinical pharmacology.

[6]  K. Koike,et al.  The Herbal Medicine Unkei‐To Stimulates Cytokine‐Induced Neutrophil Chemoattractant Production in the Pituitary Folliculo‐Stellate—Like Cell Line (TtT/GF) , 1998, American journal of reproductive immunology.

[7]  K. Koike,et al.  Evidence That Folliculo‐Stellate Cells Mediate the Inhibitory Effect of Japanese Kampo Medicine, Unkei‐To, on Growth Hormone Secretion in Rat Anterior Pituitary Cell Cultures , 1998, American journal of reproductive immunology.

[8]  P. Terranova,et al.  Review: Cytokine Involvement in Ovarian Processes , 1997, American journal of reproductive immunology.

[9]  Kazuyoshi Watanabe,et al.  Glucocorticoid-mediated Gene Suppression of Rat Cytokine-induced Neutrophil Chemoattractant CINC/gro, a Member of the Interleukin-8 Family, through Impairment of NF-B Activation (*) , 1996, The Journal of Biological Chemistry.

[10]  T. Ushiroyama,et al.  The effect of unkei-to on pituitary gonadotropin secretion and ovulation in anovulatory cycles of young women. , 1995, The American journal of Chinese medicine.

[11]  R. Norman,et al.  Localization of leukocyte subsets in the follicle wall and in the corpus luteum throughout the human menstrual cycle. , 1994, Fertility and sterility.

[12]  G. Mayrhofer,et al.  Localization of leukocyte subsets in the rat ovary during the periovulatory period. , 1993, Biology of reproduction.

[13]  S. Usuki Effects of hachimijiogan, tokishakuyakusan, keishibukuryogan, ninjinto and unkeito on estrogen and progesterone secretion in preovulatory follicles incubated in vitro. , 1991, The American journal of Chinese medicine.

[14]  Y. Taketani,et al.  82 Inhibitory effect of interleukin 1(IL-1) on the aromatase (A) activity in cultured rat granulosa cells. , 1989 .

[15]  T. Koyama,et al.  Effect of Japanese kampo medicine on hypothalamic-pituitary-ovarian function in women with ovarian insufficiency. , 1988, The American journal of Chinese medicine.

[16]  S. Usuki Effects of Tokishakuyakusan and its components on rat corpus luteum function in vitro. , 1988, The American journal of Chinese medicine.

[17]  K. Tasaka,et al.  Wen-jing-tang, a traditional Chinese herbal medicine increases luteinizing hormone release in vitro. , 1986, The American journal of Chinese medicine.

[18]  D. Magoffin,et al.  Primary culture of differentiating ovarian androgen-producing cells in defined medium. , 1982, The Journal of biological chemistry.

[19]  L. Espey Ovulation as an inflammatory reaction--a hypothesis. , 1980, Biology of reproduction.