DENN Domain Proteins: Regulators of Rab GTPases*
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P. McPherson | Peter S McPherson | Andrea L Marat | Hatem Dokainish | Hatem Dokainish | Andrea L. Marat
[1] M. Zerial,et al. Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily. , 1993, Journal of cell science.
[2] Aldo Quattrone,et al. Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2 , 2000, Nature Genetics.
[3] T. Meyer,et al. PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane , 2006, Science.
[4] T. Pawson,et al. Assembly of Cell Regulatory Systems Through Protein Interaction Domains , 2003, Science.
[5] Kenneth W Dunn,et al. Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells. , 2006, Molecular biology of the cell.
[6] J. Riley,et al. Construction of a transcription map around the gene for ataxia telangiectasia: identification of at least four novel genes. , 1997, Genomics.
[7] S. Antonarakis,et al. Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP , 2001, Nature Cell Biology.
[8] I. Mellman,et al. Rab10 is Involved in Basolateral Transport in Polarized Madin–Darby Canine Kidney Cells , 2007, Traffic.
[9] B. Prabhakar,et al. IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs , 2004, Oncogene.
[10] A. Harada,et al. Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME‐4, a coated‐pit protein , 2008, The EMBO journal.
[11] P. McPherson,et al. The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery* , 2010, The Journal of Biological Chemistry.
[12] N. Hirokawa,et al. KIF1Bβ- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD , 2008, Nature Cell Biology.
[13] J. Laporte,et al. Endosomal Phosphoinositides and Human Diseases , 2008, Traffic.
[14] T. Sasaki,et al. Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. , 2001, Molecular biology of the cell.
[15] Y. Zhang,et al. A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[16] W. Möbius,et al. Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C , 2010, The Journal of cell biology.
[17] P. Howley,et al. Identification of a human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[18] B. Goud,et al. Rab35 Regulates an Endocytic Recycling Pathway Essential for the Terminal Steps of Cytokinesis , 2006, Current Biology.
[19] R. Baron,et al. Rab3GEP Is the Non-redundant Guanine Nucleotide Exchange Factor for Rab27a in Melanocytes* , 2008, Journal of Biological Chemistry.
[20] M. Vikkula,et al. Disruption of ST5 is associated with mental retardation and multiple congenital anomalies , 2009, Journal of Medical Genetics.
[21] V. Chow,et al. DENN, a novel human gene differentially expressed in normal and neoplastic cells. , 1996, DNA sequence : the journal of DNA sequencing and mapping.
[22] H. Urlaub,et al. Quantitative Analysis of Synaptic Vesicle Rabs Uncovers Distinct Yet Overlapping Roles for Rab3a and Rab27b in Ca2+-Triggered Exocytosis , 2010, The Journal of Neuroscience.
[23] Haipeng Cheng,et al. Isolation and characterization of a human novel RAB (RAB39B) gene , 2002, Cytogenetic and Genome Research.
[24] T. Schüpbach,et al. Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. , 2008, Developmental cell.
[25] G. Superti-Furga,et al. Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway. , 2000, Human molecular genetics.
[26] Carsten Bergmann,et al. Mutation of the SBF2 gene, encoding a novel member of the myotubularin family, in Charcot-Marie-Tooth neuropathy type 4B2/11p15. , 2003, Human molecular genetics.
[27] Y. Takai,et al. Isolation and Characterization of a GDP/GTP Exchange Protein Specific for the Rab3 Subfamily Small G Proteins* , 1997, The Journal of Biological Chemistry.
[28] John Kuriyan,et al. Molecular mechanisms in signal transduction at the membrane , 2010, Nature Structural &Molecular Biology.
[29] P. Novick,et al. A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway , 2009, Proceedings of the National Academy of Sciences.
[30] B. Goud,et al. uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways. , 2001, Biochemical and biophysical research communications.
[31] J. Beneken,et al. Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[32] John Sondek,et al. A crystallographic view of interactions between Dbs and Cdc42: PH domain‐assisted guanine nucleotide exchange , 2002, The EMBO journal.
[33] Carol A. Miller,et al. Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[34] Mitsunori Fukuda,et al. Versatile role of Rab27 in membrane trafficking: focus on the Rab27 effector families. , 2005, Journal of biochemistry.
[35] C. Rongo,et al. EHBP-1 Functions with RAB-10 during Endocytic Recycling in Caenorhabditis elegans , 2010, Molecular biology of the cell.
[36] P. McPherson,et al. Variants of DENND1B associated with asthma in children. , 2010, The New England journal of medicine.
[37] G. Lienhard,et al. Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. , 2007, Cell metabolism.
[38] M. Majidi,et al. Activation of Extracellular Signal-regulated Kinase 2 by a Novel Abl-binding Protein, ST5* , 1998, The Journal of Biological Chemistry.
[39] C. Ostrowicz,et al. The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7 , 2010, Current Biology.
[40] P. McPherson,et al. The NECAP PHear domain increases clathrin accessory protein binding potential , 2007, The EMBO journal.
[41] J. Pereira-Leal,et al. Evolution of the Rab family of small GTP-binding proteins. , 2001, Journal of molecular biology.
[42] U. Suter,et al. Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2. , 2006, Human molecular genetics.
[43] A. Schievella,et al. MADD, a Novel Death Domain Protein That Interacts with the Type 1 Tumor Necrosis Factor Receptor and Activates Mitogen-activated Protein Kinase* , 1997, The Journal of Biological Chemistry.
[44] Y. Nikiforov,et al. Knockdown of IG20 gene expression renders thyroid cancer cells susceptible to apoptosis. , 2009, The Journal of clinical endocrinology and metabolism.
[45] P. McPherson,et al. The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes. , 2010, Molecular cell.
[46] Tariq Ahmad,et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.
[47] Takayuki Mōri,et al. Identification of rab12 as a vesicle‐associated small GTPase highly expressed in Sertoli cells of rat testis , 2005, Molecular reproduction and development.
[48] Ingo Ruczinski,et al. Variants of DENND1B associated with asthma in children. , 2010, The New England journal of medicine.
[49] Rab39a Binds Caspase-1 and Is Required for Caspase-1-dependent Interleukin-1β Secretion* , 2009, The Journal of Biological Chemistry.
[50] N. Mulherkar,et al. IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC , 2004, Oncogene.
[51] Wei Guo,et al. Coordination of Rab8 and Rab11 in primary ciliogenesis , 2010, Proceedings of the National Academy of Sciences.
[52] M. Eck,et al. Crystal Structure of the FERM Domain of Focal Adhesion Kinase* , 2006, Journal of Biological Chemistry.
[53] R. Ravazzolo,et al. Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma. , 2003, American journal of human genetics.
[54] Toshio Hakoshima,et al. Structural basis of the membrane‐targeting and unmasking mechanisms of the radixin FERM domain , 2000, The EMBO journal.
[55] J. Telliez,et al. LRDD, a novel leucine rich repeat and death domain containing protein. , 2000, Biochimica et biophysica acta.
[56] Timothy R Mahoney,et al. Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans. , 2006, Molecular biology of the cell.
[57] J. Gécz,et al. Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly. , 2010, American journal of human genetics.
[58] A. Baranova,et al. Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges. , 2003, Genomics.
[59] L. Samelson,et al. Rab35 and Its GAP EPI64C in T Cells Regulate Receptor Recycling and Immunological Synapse Formation* , 2008, Journal of Biological Chemistry.
[60] J. Gutkind,et al. Deletion of the COOH Terminus Converts the ST5 p70 Protein from an Inhibitor of RAS Signaling to an Activator with Transforming Activity in NIH-3T3 Cells* , 2000, The Journal of Biological Chemistry.
[61] Marino Zerial,et al. Rab proteins as membrane organizers , 2001, Nature Reviews Molecular Cell Biology.
[62] V. Rybin,et al. Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex. , 2001, Molecular biology of the cell.
[63] D. Lambright,et al. Structural Mechanisms for Regulation of Membrane Traffic by Rab GTPases , 2009, Traffic : the International Journal of Intracellular Transport.
[64] Kate S. Carroll,et al. Role of Rab9 GTPase in Facilitating Receptor Recruitment by TIP47 , 2001, Science.
[65] M. Scott,et al. Rab35 Controls Actin Bundling by Recruiting Fascin as an Effector Protein , 2009, Science.
[66] N. Mulherkar,et al. Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene. , 2008, Cancer research.
[67] D. Devor,et al. Recycling of the Ca2+-activated K+ Channel, KCa2.3, Is Dependent upon RME-1, Rab35/EPI64C, and an N-terminal Domain* , 2010, The Journal of Biological Chemistry.
[68] N. Mulherkar,et al. MADD, a Splice Variant of IG20, Is Indispensable for MAPK Activation and Protection against Apoptosis upon Tumor Necrosis Factor-α Treatment* , 2009, Journal of Biological Chemistry.
[69] B. Goud,et al. Two-hybrid System Screen with the Small GTP-binding Protein Rab6. IDENTIFICATION OF A NOVEL MOUSE GDP DISSOCIATION INHIBITOR ISOFORM AND TWO OTHER POTENTIAL PARTNERS OF Rab6 (*) , 1995, The Journal of Biological Chemistry.
[70] J. Dixon,et al. The Phosphoinositide-3-phosphatase MTMR2 Associates with MTMR13, a Membrane-associated Pseudophosphatase Also Mutated in Type 4B Charcot-Marie-Tooth Disease* , 2005, Journal of Biological Chemistry.
[71] A. Notkins,et al. The IA-2 interactome , 2005, Diabetologia.
[72] J. Presley,et al. Rab35 regulates neurite outgrowth and cell shape , 2009, FEBS letters.
[73] M. Fukuda,et al. Comprehensive Screening for Novel Rab‐Binding Proteins by GST Pull‐Down Assay Using 60 Different Mammalian Rabs ‡ , 2010, Traffic.
[74] Y. Kalaidzidis,et al. Rab Conversion as a Mechanism of Progression from Early to Late Endosomes , 2005, Cell.
[75] J. Mandel,et al. The myotubularin family: from genetic disease to phosphoinositide metabolism. , 2001, Trends in genetics : TIG.
[76] O. Bakke,et al. Major Histocompatibility Complex Class II-Peptide Complexes Internalize Using a Clathrin- and Dynamin-independent Endocytosis Pathway* , 2008, Journal of Biological Chemistry.
[77] R. Schekman,et al. Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway. , 2007, Molecular biology of the cell.
[78] B. Goud,et al. Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain. , 2009, Structure.
[79] N. Hayward,et al. Identification of ARHGEF17, DENND2D, FGFR3, and RB1 mutations in melanoma by inhibition of nonsense‐mediated mRNA decay , 2008, Genes, chromosomes & cancer.
[80] F. Waharte,et al. Rab6‐interacting Protein 1 Links Rab6 and Rab11 Function , 2007, Traffic.
[81] R. Dominguez,et al. Large nucleotide‐dependent conformational change in Rab28 , 2008, FEBS letters.
[82] P. McPherson,et al. Non-stoichiometric Relationship between Clathrin Heavy and Light Chains Revealed by Quantitative Comparative Proteomics of Clathrin-coated Vesicles from Brain and Liver*S , 2005, Molecular & Cellular Proteomics.
[83] J. Bonifacino,et al. Assembly of the Biogenesis of Lysosome-related Organelles Complex-3 (BLOC-3) and Its Interaction with Rab9* , 2010, The Journal of Biological Chemistry.
[84] H. Stenmark. Rab GTPases as coordinators of vesicle traffic , 2009, Nature Reviews Molecular Cell Biology.
[85] Marino Zerial,et al. Identification of the Switch in Early-to-Late Endosome Transition , 2010, Cell.
[86] J. Dixon,et al. Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[87] Myeong Sup Lee,et al. Rab35 Mediates Transport of Cdc42 and Rac1 to the Plasma Membrane during Phagocytosis , 2010, Molecular and Cellular Biology.
[88] S. Harper,et al. Connecdenn, A Novel DENN Domain-Containing Protein of Neuronal Clathrin-Coated Vesicles Functioning in Synaptic Vesicle Endocytosis , 2006, The Journal of Neuroscience.
[89] D. Rigden,et al. Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors , 2010, The Journal of cell biology.
[90] J. Staunton,et al. aex-3 Encodes a Novel Regulator of Presynaptic Activity in C. elegans , 1997, Neuron.
[91] Florence Demenais,et al. A large-scale, consortium-based genomewide association study of asthma. , 2010, The New England journal of medicine.
[92] D. Lambright,et al. Structure, Exchange Determinants, and Family-Wide Rab Specificity of the Tandem Helical Bundle and Vps9 Domains of Rabex-5 , 2004, Cell.
[93] M. Majidi,et al. Expression of an isoform of the novel signal transduction protein ST5 is linked to cell morphology , 1999, Oncogene.