Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusions
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Shujiro Okuda | R. Verhaak | K. Yoshihara | M. Komatsu | T. Enomoto | H. Itamochi | T. Motoyama | I. Inoue | Tetsuya Saito | Ryosuke Ishimura | Y. Mori | Y. Aoki | H. Nakaoka | Cristine R. Casingal | Seiya Sato | K. Suda | Ryo Tamura | T. Ishiguro | J. Martinez-Ledesma | Kaoru Yamawaki | H. Xin | Yutaro Mori
[1] C. Bersani,et al. In vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines. , 2019, Oncology letters.
[2] Haitao Zhao,et al. Precision oncology for gallbladder cancer: insights from genetic alterations and clinical practice. , 2019, Annals of translational medicine.
[3] Yurong Wang,et al. Construction and Analysis of lncRNA-Mediated ceRNA Network in Cervical Squamous Cell Carcinoma by Weighted Gene Co-Expression Network Analysis , 2019, Medical science monitor : international medical journal of experimental and clinical research.
[4] W. Gu,et al. Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors , 2019, Journal of enzyme inhibition and medicinal chemistry.
[5] S. Stokley,et al. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13–17 Years — United States, 2017 , 2018, MMWR. Morbidity and mortality weekly report.
[6] R. Bernards,et al. A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma. , 2017, European urology.
[7] K. Yoshihara,et al. Sox2‐dependent inhibition of p21 is associated with poor prognosis of endometrial cancer , 2017, Cancer science.
[8] J. Datta,et al. Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398 , 2017, Molecular Cancer Therapeutics.
[9] Gad Getz,et al. Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma. , 2017, Cancer discovery.
[10] J. Macneil,et al. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13-17 Years - United States, 2015. , 2016, MMWR. Morbidity and mortality weekly report.
[11] K. Okamura,et al. Human genetic variation database, a reference database of genetic variations in the Japanese population , 2016, Journal of Human Genetics.
[12] A. N. Meyer,et al. Oncogenic Gene Fusion FGFR3-TACC3 Is Regulated by Tyrosine Phosphorylation , 2016, Molecular Cancer Research.
[13] James Y. Zou. Analysis of protein-coding genetic variation in 60,706 humans , 2015, Nature.
[14] Shujiro Okuda,et al. Novel kinase fusion transcripts found in endometrial cancer , 2015, Scientific Reports.
[15] Gabor T. Marth,et al. A global reference for human genetic variation , 2015, Nature.
[16] Razelle Kurzrock,et al. The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing , 2015, Clinical Cancer Research.
[17] S. Asthana,et al. RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer , 2015, Nature Medicine.
[18] S. Stokley,et al. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13–17 Years — United States, 2014 , 2015, MMWR. Morbidity and mortality weekly report.
[19] R. Kishi,et al. HPV vaccination crisis in Japan , 2015, The Lancet.
[20] C. Mathers,et al. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 , 2015, International journal of cancer.
[21] Wentao Yang,et al. Comprehensive analysis of targetable oncogenic mutations in chinese cervical cancers , 2014, Oncotarget.
[22] R. Verhaak,et al. The landscape and therapeutic relevance of cancer-associated transcript fusions , 2014, Oncogene.
[23] Mingming Jia,et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer , 2014, Nucleic Acids Res..
[24] Zhi‐hua Liu,et al. Recurrent FGFR3-TACC3 fusion gene in nasopharyngeal carcinoma , 2014, Cancer biology & therapy.
[25] Nicolas Stransky,et al. The landscape of kinase fusions in cancer , 2014, Nature Communications.
[26] John N. Weinstein,et al. PRADA: pipeline for RNA sequencing data analysis , 2014, Bioinform..
[27] C. Meijer,et al. Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions , 2014, Nature Reviews Cancer.
[28] Lei Wang,et al. FGFR1/3 Tyrosine Kinase Fusions Define a Unique Molecular Subtype of Non–Small Cell Lung Cancer , 2014, Clinical Cancer Research.
[29] Björn Usadel,et al. Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..
[30] Trevor J Pugh,et al. Landscape of genomic alterations in cervical carcinomas , 2013, Nature.
[31] Jeffrey A. Engelman,et al. Tyrosine kinase gene rearrangements in epithelial malignancies , 2013, Nature Reviews Cancer.
[32] Nickolay A. Khazanov,et al. Identification of targetable FGFR gene fusions in diverse cancers. , 2013, Cancer discovery.
[33] K. Gardner,et al. Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules. , 2013, ACS chemical biology.
[34] M. Nykter,et al. The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. , 2013, The Journal of clinical investigation.
[35] M. Knowles,et al. Oncogenic FGFR3 gene fusions in bladder cancer , 2012, Human molecular genetics.
[36] Y. Li,et al. Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis , 2012, Molecular and Cellular Biochemistry.
[37] David M. Thomas,et al. FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor. , 2012, Cancer discovery.
[38] D. Brat,et al. Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma , 2012, Science.
[39] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[40] Tatiana Popova,et al. Supplementary Methods , 2012, Acta Neuropsychiatrica.
[41] M. Roizen,et al. Hallmarks of Cancer: The Next Generation , 2012 .
[42] Benjamin J. Raphael,et al. Integrated Genomic Analyses of Ovarian Carcinoma , 2011, Nature.
[43] M. DePristo,et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data , 2011, Nature Genetics.
[44] P. Schultz,et al. A small molecule accelerates neuronal differentiation in the adult rat , 2010, Proceedings of the National Academy of Sciences.
[45] M. DePristo,et al. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.
[46] H. Hakonarson,et al. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.
[47] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[48] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[49] R. Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[50] K. Schulze-Osthoff,et al. The Transforming Acidic Coiled Coil 3 Protein Is Essential for Spindle-dependent Chromosome Alignment and Mitotic Survival* , 2007, Journal of Biological Chemistry.
[51] D. Bar-Sagi,et al. Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. , 2004, Cancer cell.
[52] F. Gergely,et al. The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[53] T. Tamaya,et al. Clinical implications of expression of interleukin 8 related to angiogenesis in uterine cervical cancers. , 2000, Cancer research.