Reactions to UV damage in the model archaeon Sulfolobus solfataricus.

Mechanisms involved in DNA repair and genome maintenance are essential for all organisms on Earth and have been studied intensively in bacteria and eukaryotes. Their analysis in extremely thermophilic archaea offers the opportunity to discover strategies for maintaining genome integrity of the relatively little explored third domain of life, thereby shedding light on the diversity and evolution of these central and important systems. These studies might also reveal special adaptations that are essential for life at high temperature. A number of investigations of the hyperthermophilic and acidophilic crenarchaeote Sulfolobus solfataricus have been performed in recent years. Mostly, the reactions to DNA damage caused by UV light have been analysed. Whole-genome transcriptomics have demonstrated that a UV-specific response in S. solfataricus does not involve the transcriptional induction of DNA-repair genes and it is therefore different from the well-known SOS response in bacteria. Nevertheless, the UV response in S. solfataricus is impressively complex and involves many different levels of action, some of which have been elucidated and shed light on novel strategies for DNA repair, while others involve proteins of unknown function whose actions in the cell remain to be elucidated. The present review summarizes and discusses recent investigations on the UV response of S. solfataricus on both the molecular biological and the cellular levels.

[1]  M. Wagner,et al.  UV‐inducible cellular aggregation of the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by pili formation , 2008, Molecular microbiology.

[2]  T. Paull,et al.  The P. furiosus Mre11/Rad50 Complex Promotes 5′ Strand Resection at a DNA Double-Strand Break , 2008, Cell.

[3]  Lester G. Carter,et al.  Structure of the DNA Repair Helicase XPD , 2008, Cell.

[4]  M. F. White,et al.  The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius , 2008, BMC Molecular Biology.

[5]  U. Hübscher,et al.  Deinococcus radiodurans: What Belongs to the Survival Kit? , 2008, Critical reviews in biochemistry and molecular biology.

[6]  M. F. White,et al.  Responses of hyperthermophilic crenarchaea to UV irradiation , 2007, Genome Biology.

[7]  Christoph W. Sensen,et al.  Response of the Hyperthermophilic Archaeon Sulfolobus solfataricus to UV Damage , 2007, Journal of bacteriology.

[8]  Ying Feng,et al.  Divergent functions of multiple eukaryote-like Orc1/Cdc6 proteins on modulating the loading of the MCM helicase onto the origins of the hyperthermophilic archaeon Sulfolobus solfataricus P2. , 2007, Biochemical and biophysical research communications.

[9]  Sabrina Fröls,et al.  Elucidating the transcription cycle of the UV-inducible hyperthermophilic archaeal virus SSV1 by DNA microarrays. , 2007, Virology.

[10]  R. Bernander,et al.  Genome-wide transcription map of an archaeal cell cycle , 2007, Proceedings of the National Academy of Sciences.

[11]  M. Rossi,et al.  Lack of strand-specific repair of UV-induced DNA lesions in three genes of the archaeon Sulfolobus solfataricus. , 2007, Journal of molecular biology.

[12]  M. F. White,et al.  Equal rates of repair of DNA photoproducts in transcribed and non‐transcribed strands in Sulfolobus solfataricus , 2007, Molecular microbiology.

[13]  Y. Kawarabayasi,et al.  Crystal structure of archaeal photolyase from Sulfolobus tokodaii with two FAD molecules: implication of a novel light-harvesting cofactor. , 2006, Journal of molecular biology.

[14]  J. Haber,et al.  Perspectives Anecdotal, Historical and Critical Commentaries on Genetics Chromosome Breakage and Repair , 2022 .

[15]  S. Bell,et al.  The Chromosome Replication Machinery of the Archaeon Sulfolobus solfataricus* , 2006, Journal of Biological Chemistry.

[16]  M. F. White,et al.  Archaeal DNA replication and repair. , 2005, Current opinion in microbiology.

[17]  M. Smid,et al.  Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV‐induced DNA breaks , 2005, The EMBO journal.

[18]  D. Grogan,et al.  Conjugational Genetic Exchange in the Hyperthermophilic Archaeon Sulfolobus acidocaldarius: Intragenic Recombination with Minimal Dependence on Marker Separation , 2005, Journal of bacteriology.

[19]  M. Rossi,et al.  Reverse Gyrase Recruitment to DNA after UV Light Irradiation in Sulfolobus solfataricus* , 2004, Journal of Biological Chemistry.

[20]  J. Tainer,et al.  Structure and function of the double-strand break repair machinery. , 2004, DNA repair.

[21]  D. Grogan.  Stability and Repair of DNA in Hyperthermophilic Archaea , 2004 .

[22]  E V Koonin,et al.  A bipolar DNA helicase gene, herA, clusters with rad50, mre11 and nurA genes in thermophilic archaea. , 2004, Nucleic acids research.

[23]  Rolf Bernander,et al.  Identification of Two Origins of Replication in the Single Chromosome of the Archaeon Sulfolobus solfataricus , 2004, Cell.

[24]  M. F. White,et al.  Transcriptional response to DNA damage in the archaeon Sulfolobus solfataricus. , 2003, Nucleic acids research.

[25]  Takehiko Nohmi,et al.  Processing of DNA lesions by archaeal DNA polymerases from Sulfolobus solfataricus. , 2003, Nucleic acids research.

[26]  S. Bell,et al.  DNA replication in the hyperthermophilic archaeon Sulfolobus solfataricus. , 2003, Biochemical Society transactions.

[27]  M. F. White.  Archaeal DNA repair: paradigms and puzzles. , 2003, Biochemical Society transactions.

[28]  S. Jackson,et al.  The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling , 2002, Nature Reviews Molecular Cell Biology.

[29]  R. Woodgate,et al.  Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. , 2001, Nucleic acids research.

[30]  A. Kuzminov.  Single-strand interruptions in replicating chromosomes cause double-strand breaks , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[31]  Mark A. Ragan,et al.  The complete genome of the crenarchaeon Sulfolobus solfataricus P2 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[32]  J. Drake,et al.  Genetic fidelity under harsh conditions: Analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[33]  D. Grogan,et al.  Characterization of Intragenic Recombination in a Hyperthermophilic Archaeon via Conjugational DNA Exchange , 2001, Journal of bacteriology.

[34]  D. Grogan.  The question of DNA repair in hyperthermophilic archaea. , 2000, Trends in microbiology.

[35]  D. Grogan,et al.  UV stimulation of chromosomal marker exchange in Sulfolobus acidocaldarius: implications for DNA repair, conjugation and homologous recombination at extremely high temperatures. , 1999, Genetics.

[36]  Y. Ishino,et al.  Archaeal DNA replication: identifying the pieces to solve a puzzle. , 1999, Genetics.

[37]  D. Grogan.  Hyperthermophiles and the problem of DNA instability , 1998, Molecular microbiology.

[38]  Joel P. Brockman,et al.  RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange. , 1998, Genes & development.

[39]  A. Poplawski,et al.  Nucleoid structure and distribution in thermophilic Archaea , 1997, Journal of bacteriology.

[40]  D. Grogan,et al.  Genetic responses of the thermophilic archaeon Sulfolobus acidocaldarius to short-wavelength UV light , 1997, Journal of bacteriology.

[41]  P. Hartzell,et al.  Stress-Induced Production of Biofilm in the Hyperthermophile Archaeoglobus fulgidus , 1997, Applied and environmental microbiology.

[42]  W. Doolittle,et al.  Gene duplications in evolution of archaeal family B DNA polymerases , 1997, Journal of bacteriology.

[43]  S. Sandler,et al.  recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae. , 1996, Nucleic acids research.

[44]  C. Schleper,et al.  Viruses, plasmids and other genetic elements of thermophilic and hyperthermophilic Archaea. , 1996, FEMS microbiology reviews.

[45]  C. Schleper,et al.  The particle SSV1 from the extremely thermophilic archaeon Sulfolobus is a virus: demonstration of infectivity and of transfection with viral DNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[46]  W. D. Reiter,et al.  Analysis of transcription in the archaebacterium Sulfolobus indicates that archaebacterial promoters are homologous to eukaryotic pol II promoters , 1988, Nucleic Acids Res..

[47]  W. Zillig,et al.  Gene expression in archaebacteria: Physical mapping of constitutive and UV-inducible transcripts from the Sulfolobus virus-like particle SSV1 , 1987, Molecular and General Genetics MGG.

[48]  W. Zillig,et al.  SAV 1, a temperate u.v.‐inducible DNA virus‐like particle from the archaebacterium Sulfolobus acidocaldarius isolate B12 , 1984, The EMBO journal.

[49]  T. Bonura,et al.  Enzymatic production of deoxyribonucleic acid double-strand breaks after ultraviolet irradiation of Escherichia coli K-12 , 1975, Journal of bacteriology.

[50]  S. Kowalczykowski,et al.  DNA recombination and repair in the archaea. , 2001, Advances in applied microbiology.

[51]  S. Bell,et al.  Transcription in Archaea. , 1998, Cold Spring Harbor symposia on quantitative biology.