Trends in allergy prevalence among children aged 0–17 years by asthma status, United States, 2001–2013

Abstract Objectives: Children with asthma and allergies—particularly food and/or multiple allergies–are at risk for adverse asthma outcomes. This analysis describes allergy prevalence trends among US children by asthma status. Methods: We analyzed 2001–2013 National Health Interview Survey data for children aged 0–17 years. We estimated trends for reported respiratory, food, and skin allergy and the percentage of children with one, two, or all three allergy types by asthma status. We estimated unadjusted trends, and among children with asthma, adjusted associations between demographic characteristics and allergy. Results: Prevalence of any allergy increased by 0.3 percentage points annually among children without asthma but not among children with asthma. However, underlying patterns changed among children with asthma: food and skin allergy prevalence increased as did the percentage with all three allergy types. Among children with asthma, risk was higher among younger and non-Hispanic black children for reported skin allergy, among non-Hispanic white children for reported respiratory allergy, and among non-poor children for food and respiratory allergies. Prevalence of having one allergy type decreased by 0.50 percentage points annually, while the percent with all three types increased 0.2 percentage points annually. Non-poor and non-Hispanic white children with asthma were more likely to have multiple allergy types. Conclusions: While overall allergy prevalence among children with asthma remained stable, patterns in reported allergy type and number suggested a greater proportion may be at risk of adverse asthma outcomes associated with allergy: food allergy increased as did the percentage with all three allergy types.

[1]  Alan E. Simon,et al.  Trends in racial disparities for asthma outcomes among children 0 to 17 years, 2001-2010. , 2014, The Journal of allergy and clinical immunology.

[2]  N. Rabinovitch,et al.  Eczema and race as combined determinants for differential response to step-up asthma therapy. , 2014, The Journal of allergy and clinical immunology.

[3]  A. Ozonoff,et al.  Food allergy and increased asthma morbidity in a School-based Inner-City Asthma Study. , 2013, The journal of allergy and clinical immunology. In practice.

[4]  L. Akinbami,et al.  Trends in allergic conditions among children: United States, 1997-2011. , 2013, NCHS data brief.

[5]  E. Bleecker,et al.  Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. , 2012, The Journal of allergy and clinical immunology.

[6]  A. Nowak‐Wegrzyn,et al.  National Prevalence and Risk Factors for Food Allergy and Relationship to Asthma: Results From the National Health and Nutrition Examination Survey 2005–2006 , 2011, Pediatrics.

[7]  J. Castro-Rodriguez The Asthma Predictive Index: early diagnosis of asthma , 2011, Current opinion in allergy and clinical immunology.

[8]  G. Giles,et al.  Childhood eczema and rhinitis predict atopic but not nonatopic adult asthma: a prospective cohort study over 4 decades. , 2011, The Journal of allergy and clinical immunology.

[9]  D. Zeldin,et al.  National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005-2006. , 2010, The Journal of allergy and clinical immunology.

[10]  J. Spergel,et al.  From atopic dermatitis to asthma: the atopic march. , 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[11]  A. Branum,et al.  Food Allergy Among Children in the United States , 2009, Pediatrics.

[12]  J. Celedón,et al.  Asthma and ethnic minorities: socioeconomic status and beyond , 2009, Current opinion in allergy and clinical immunology.

[13]  T. Haselkorn,et al.  Racial disparities in asthma-related health outcomes in severe or difficult-to-treat asthma. , 2008, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[14]  J. Glutting,et al.  Food allergy and asthma morbidity in children , 2007, Pediatric pulmonology.

[15]  R. Neugebauer,et al.  Comparison of patterns of allergen sensitization among inner-city Hispanic and African American children with asthma. , 2006, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[16]  R. Strange,et al.  Asthma severity and atopy: how clear is the relationship? , 2006, Archives of Disease in Childhood.

[17]  H. Sampson,et al.  Food allergen sensitization in inner-city children with asthma. , 2005, The Journal of allergy and clinical immunology.

[18]  G. Roberts,et al.  Food allergy as a risk factor for life-threatening asthma in childhood: a case-controlled study. , 2003, The Journal of allergy and clinical immunology.

[19]  K. Savolainen,et al.  Allergen-specific immunoglobulin E antibodies in wheezing infants: the risk for asthma in later childhood. , 2003, Pediatrics.

[20]  U. Wahn,et al.  Natural course of sensitization to food and inhalant allergens during the first 6 years of life. , 1999, The Journal of allergy and clinical immunology.

[21]  A. Burks,et al.  Prevalence of peanut and tree nut allergy in the US determined by a random digit dial telephone survey. , 1999, The Journal of allergy and clinical immunology.

[22]  P. Gergen,et al.  The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. , 1997, The New England journal of medicine.

[23]  W. Morgan,et al.  Asthma and wheezing in the first six years of life. The Group Health Medical Associates. , 1995, The New England journal of medicine.

[24]  K. Lue,et al.  Coexistence of allergic diseases: patterns and frequencies. , 2012, Allergy and asthma proceedings.

[25]  P. Briefs Health Resources and Services Administration | Maternal and Child Health Bureau , 2010 .

[26]  T. Raghunathan,et al.  Multiple Imputation of Family Income and Personal Earnings in the National Health Interview Survey: Methods and Examples , 2008 .

[27]  Michael Witt,et al.  SUDAAN language manual, release 9.0: , 2003 .

[28]  A. Ponsonby,et al.  Which clinical subgroups within the spectrum of child asthma are attributable to atopy? , 2002, Chest.

[29]  Ennis,et al.  THE ROLE OF COCKROACH ALLERGY AND EXPOSURE TO COCKROACH ALLERGEN IN CAUSING MORBIDITY AMONG INNER-CITY CHILDREN WITH ASTHMA , 2000 .

[30]  Food Allergy among Children in the United States , 2022 .