Molecular mechanisms involved in inflammasome activation.
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[1] J. Tschopp,et al. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes , 2009, Nature.
[2] J. Tschopp,et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence , 2009, Nature.
[3] R. Webby,et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. , 2009, Immunity.
[4] J. Ting,et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. , 2009, Immunity.
[5] C. Marsh,et al. Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection , 2009, PLoS pathogens.
[6] F. Martinon,et al. The inflammasomes: guardians of the body. , 2009, Annual review of immunology.
[7] Seth L Masters,et al. Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*). , 2009, Annual review of immunology.
[8] G. Superti-Furga,et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome , 2009, Nature Immunology.
[9] Jasmyn A. Dunn,et al. HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA , 2009, Science.
[10] B. Cookson,et al. Pyroptosis: host cell death and inflammation , 2009, Nature Reviews Microbiology.
[11] Daniel R. Caffrey,et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC , 2009, Nature.
[12] E. Alnemri,et al. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA , 2009, Nature.
[13] J. Tschopp,et al. Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome , 2009, Proceedings of the National Academy of Sciences.
[14] Akiko Iwasaki,et al. Inflammasome recognition of influenza virus is essential for adaptive immune responses , 2009, The Journal of experimental medicine.
[15] N. Warner,et al. Function of Nod‐like receptors in microbial recognition and host defense , 2009, Immunological reviews.
[16] T. Vanden Berghe,et al. Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes *S , 2008, Molecular & Cellular Proteomics.
[17] Gordon D. Brown,et al. The fungal pattern recognition receptor, Dectin-1, and the associated cluster of C-type lectin-like receptors , 2008, FEMS microbiology letters.
[18] Shizuo Akira,et al. Toll‐like Receptor and RIG‐1‐like Receptor Signaling , 2008, Annals of the New York Academy of Sciences.
[19] Sky W. Brubaker,et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin , 2008, Nature Immunology.
[20] K. Rock,et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.
[21] G. Núñez,et al. The Nlrp3 inflammasome is critical for aluminium hydroxide‐mediated IL‐1β secretion but dispensable for adjuvant activity , 2008, European journal of immunology.
[22] K. Moore,et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-β , 2008, Nature Immunology.
[23] Richard A. Flavell,et al. The Nalp3 inflammasome is essential for the development of silicosis , 2008, Proceedings of the National Academy of Sciences.
[24] F. Re,et al. Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP31 , 2008, The Journal of Immunology.
[25] Richard A. Flavell,et al. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants , 2008, Nature.
[26] V. Nizet,et al. A NOD2–NALP1 complex mediates caspase-1-dependent IL-1β secretion in response to Bacillus anthracis infection and muramyl dipeptide , 2008, Proceedings of the National Academy of Sciences.
[27] A. Aderem,et al. Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection12 , 2008, The Journal of Immunology.
[28] A. Surprenant,et al. P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage1 , 2008, The Journal of Immunology.
[29] J. Tschopp,et al. Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica , 2008, Science.
[30] J. Ting,et al. NLRs at the intersection of cell death and immunity , 2008, Nature Reviews Immunology.
[31] A. Takaoka,et al. Cytosolic DNA recognition for triggering innate immune responses. , 2008, Advanced drug delivery reviews.
[32] S. Ehlers,et al. Mycobacterium tuberculosis prevents inflammasome activation. , 2008, Cell host & microbe.
[33] K. Rock,et al. How dying cells alert the immune system to danger , 2008, Nature Reviews Immunology.
[34] G. Núñez,et al. Pannexin-1-Mediated Intracellular Delivery of Muramyl Dipeptide Induces Caspase-1 Activation via Cryopyrin/NLRP3 Independently of Nod21 , 2008, The Journal of Immunology.
[35] J. Tschopp,et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response , 2008, Nature.
[36] G. Kalliolias,et al. The future of the IL-1 receptor antagonist anakinra: from rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis , 2008 .
[37] S. Nagata. Autoimmune diseases caused by defects in clearing dead cells and nuclei expelled from erythroid precursors , 2007, Immunological reviews.
[38] J. Tschopp,et al. The inflammasome: a danger sensing complex triggering innate immunity. , 2007, Current opinion in immunology.
[39] Yao-Hui Sun,et al. Injection of Flagellin into the Host Cell Cytosol by Salmonella enterica Serotype Typhimurium* , 2007, Journal of Biological Chemistry.
[40] M. Yoneyama,et al. RIG-I family RNA helicases: cytoplasmic sensor for antiviral innate immunity. , 2007, Cytokine & growth factor reviews.
[41] J. Tschopp,et al. From inflammasomes to fevers, crystals and hypertension: how basic research explains inflammatory diseases. , 2007, Trends in molecular medicine.
[42] A. Aderem,et al. TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system , 2007, Seminars in Immunopathology.
[43] C. Sasakawa,et al. Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages , 2007, PLoS pathogens.
[44] K. Honda,et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response , 2007, Nature.
[45] G. Dubyak,et al. Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria* , 2007, Journal of Biological Chemistry.
[46] P. Vandenabeele,et al. Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. , 2007, Immunity.
[47] J. Ting,et al. Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions. , 2007, Microbes and infection.
[48] Sheri L. Riccardi,et al. NALP1 in vitiligo-associated multiple autoimmune disease. , 2007, The New England journal of medicine.
[49] J. Tschopp,et al. A pilot study of IL-1 inhibition by anakinra in acute gout , 2007, Arthritis research & therapy.
[50] N. Volkmann,et al. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. , 2007, Molecular cell.
[51] P. Sansonetti,et al. Sensing of bacteria: NOD a lonely job. , 2007, Current opinion in microbiology.
[52] J. Ting,et al. Cutting Edge: Monarch-1 Suppresses Non-Canonical NF-κB Activation and p52-Dependent Chemokine Expression in Monocytes1 , 2007, The Journal of Immunology.
[53] David Miller,et al. Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA*> , 2006, Journal of Biological Chemistry.
[54] A. Surprenant,et al. Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor , 2006, The EMBO journal.
[55] H. Yoshikawa,et al. Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages , 2006, Nature.
[56] Michael Karin,et al. Intracellular pattern recognition receptors in the host response , 2006, Nature.
[57] J. Bertin,et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages , 2006, Nature Immunology.
[58] Alan Aderem,et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf , 2006, Nature Immunology.
[59] F. Di Virgilio,et al. The P2X7 Receptor: A Key Player in IL-1 Processing and Release1 , 2006, The Journal of Immunology.
[60] R. Siegel. Caspases at the crossroads of immune-cell life and death , 2006, Nature Reviews Immunology.
[61] F. Martinon,et al. Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.
[62] V. Dixit,et al. Cryopyrin activates the inflammasome in response to toxins and ATP , 2006, Nature.
[63] W. Dietrich,et al. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin , 2006, Nature Genetics.
[64] M. Braunstein,et al. The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals* , 2005, Journal of Biological Chemistry.
[65] G. Dubyak,et al. Potentiation of Caspase-1 Activation by the P2X7 Receptor Is Dependent on TLR Signals and Requires NF-κB-Driven Protein Synthesis1 , 2005, The Journal of Immunology.
[66] F. Martinon,et al. NLRs join TLRs as innate sensors of pathogens. , 2005, Trends in immunology.
[67] J. Trapani,et al. Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2. , 2005, Biochemical and biophysical research communications.
[68] S. Akira,et al. Toll-like receptors in innate immunity. , 2004, International immunology.
[69] V. Dixit,et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf , 2004, Nature.
[70] G. Núñez,et al. Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC. , 2004, The Journal of biological chemistry.
[71] F. Martinon,et al. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. , 2004, Immunity.
[72] James E. Evans,et al. Molecular identification of a danger signal that alerts the immune system to dying cells , 2003, Nature.
[73] Y. Ogura,et al. Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product. , 2003, Biochemical and biophysical research communications.
[74] C. Dinarello,et al. The IL-1 family and inflammatory diseases. , 2002, Clinical and experimental rheumatology.
[75] F. Martinon,et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.
[76] H. Xin,et al. Cytoplasmic localization of the interferon‐inducible protein that is encoded by the AIM2 (absent in melanoma) gene from the 200‐gene family , 2000, FEBS letters.
[77] J. Corbett,et al. Double-stranded RNA-induced Inducible Nitric-oxide Synthase Expression and Interleukin-1 Release by Murine Macrophages Requires NF-κB Activation* , 1998, The Journal of Biological Chemistry.
[78] A. Churg,et al. Mechanisms in the pathogenesis of asbestosis and silicosis. , 1998, American journal of respiratory and critical care medicine.
[79] J. Hiscott,et al. Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop , 1993, Molecular and cellular biology.