Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation
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Jacob D. Jaffe | Charles Y. Lin | W. Hahn | D. Neuberg | K. Stegmaier | A. Schinzel | T. Sullivan | J. Bradner | S. Sallan | Elizabeth C. Townsend | M. Harris | G. Alexe | L. Silverman | A. Lane | M. Bustin | D. Pellman | Hubo Li | Huiyun Liu | Shuo-chieh Wu | K. Stevenson | S. Izraeli | D. Weinstock | B. Chapuy | Jordan E. Taylor | J. Crispino | S. Malinge | A. Yoda | G. Te Kronnie | Trevor Tivey | Anna C. Schinzel | Timothy J. Sullivan | Tovah A. Day | Diederik van Bodegom | Sébastien Malinge | G. te Kronnie
[1] David A. Orlando,et al. Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers , 2013, Cell.
[2] Yan Liu,et al. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations , 2012, Nature.
[3] Sarah Filippi,et al. Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21 , 2012, Proceedings of the National Academy of Sciences.
[4] Charles Y. Lin,et al. Transcriptional Amplification in Tumor Cells with Elevated c-Myc , 2012, Cell.
[5] John M. Ashton,et al. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. , 2012, Cell stem cell.
[6] Christopher J. Schofield,et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response , 2012, Nature.
[7] Steven L Salzberg,et al. Fast gapped-read alignment with Bowtie 2 , 2012, Nature Methods.
[8] Jacob D. Jaffe,et al. Quantitative Assessment of Chromatin Immunoprecipitation Grade Antibodies Directed against Histone Modifications Reveals Patterns of Co-occurring Marks on Histone Protein Molecules* , 2012, Molecular & Cellular Proteomics.
[9] David R. Kelley,et al. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.
[10] Dustin E. Schones,et al. The Chromatin-binding Protein HMGN1 Regulates the Expression of Methyl CpG-binding Protein 2 (MECP2) and Affects the Behavior of Mice* , 2011, The Journal of Biological Chemistry.
[11] Syed Haider,et al. Ensembl BioMarts: a hub for data retrieval across taxonomic space , 2011, Database J. Biol. Databases Curation.
[12] D. Weinstock,et al. Repair at Single Targeted DNA Double-Strand Breaks in Pluripotent and Differentiated Human Cells , 2011, PloS one.
[13] R. Reeves,et al. Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome. , 2011, Cancer research.
[14] Michael Bustin,et al. Effects of HMGN variants on the cellular transcription profile , 2011, Nucleic acids research.
[15] Clifford A. Meyer,et al. Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. , 2010, Developmental cell.
[16] Gary D Bader,et al. Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation , 2010, PloS one.
[17] Trey Ideker,et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates the B cell fate , 2010, Nature Immunology.
[18] S. Richards,et al. Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. , 2010, The Lancet. Oncology.
[19] Cole Trapnell,et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.
[20] E. Domany,et al. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. , 2010, Blood.
[21] Mark D. Robinson,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[22] E. Domany,et al. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. , 2010, Blood.
[23] P. D. Dal Cin,et al. Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia , 2009, Proceedings of the National Academy of Sciences.
[24] J. Downing,et al. Rearrangement of CRLF2 in B-progenitor– and Down syndrome–associated acute lymphoblastic leukemia , 2009, Nature Genetics.
[25] D. C. Cabelof,et al. Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome. , 2009, Blood.
[26] Takashi Akasaka,et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. , 2009, Blood.
[27] N. Heisterkamp,et al. Pre–B cell receptor–mediated cell cycle arrest in Philadelphia chromosome–positive acute lymphoblastic leukemia requires IKAROS function , 2009, The Journal of experimental medicine.
[28] J. T. Kadonaga,et al. HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility. , 2009, Molecular cell.
[29] M. Loh,et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia , 2009, Proceedings of the National Academy of Sciences.
[30] J. Whitlock,et al. Malignancy in children with trisomy 21. , 2009, The oncologist.
[31] R. Foà,et al. Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. , 2008, Blood.
[32] Clifford A. Meyer,et al. Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.
[33] A. Regev,et al. An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors , 2008, Nature Genetics.
[34] R. Pedersen,et al. Robust, Persistent Transgene Expression in Human Embryonic Stem Cells Is Achieved with AAVS1‐Targeted Integration , 2008, Stem cells.
[35] M. Robinson,et al. Small-sample estimation of negative binomial dispersion, with applications to SAGE data. , 2007, Biostatistics.
[36] Mark D. Robinson,et al. Moderated statistical tests for assessing differences in tag abundance , 2007, Bioinform..
[37] T. Mikkelsen,et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells , 2007, Nature.
[38] S. Raimondi,et al. Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia , 2007, Genes, chromosomes & cancer.
[39] R. A. Etten,et al. Requirement for CD44 in homing and engraftment of BCR-ABL–expressing leukemic stem cells , 2006, Nature Medicine.
[40] Jun Song,et al. CEAS: cis-regulatory element annotation system , 2006, Nucleic Acids Res..
[41] J. Mesirov,et al. GenePattern 2.0 , 2006, Nature Genetics.
[42] James A. Cuff,et al. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.
[43] D. Weinstock,et al. Alternative Pathways for the Repair of RAG-Induced DNA Breaks , 2006, Molecular and Cellular Biology.
[44] D. Weinstock,et al. Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase. , 2006, Methods in enzymology.
[45] R. Myers,et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data , 2005, Nucleic acids research.
[46] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[47] M. Bustin,et al. Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3 , 2005, The EMBO journal.
[48] C. Bloomfield,et al. Additional cytogenetic abnormalities in adults with Philadelphia chromosome‐positive acute lymphoblastic leukaemia: a study of the Cancer and Leukaemia Group B , 2004, British journal of haematology.
[49] Michael Bustin,et al. Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin , 2003, The EMBO journal.
[50] T. Speed,et al. Summaries of Affymetrix GeneChip probe level data. , 2003, Nucleic acids research.
[51] T. Misteli,et al. Competition between histone H1 and HMGN proteins for chromatin binding sites , 2002, EMBO reports.
[52] M. Oshimura,et al. Functional expression and germline atransmission of a human chromosome fragment in chimaeric mice , 1997, Nature Genetics.
[53] R. Reeves,et al. Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin. , 1995, DNA and cell biology.
[54] R. Bronson,et al. A mouse model for Down syndrome exhibits learning and behaviour deficits , 1995, Nature Genetics.
[55] E. Wagner,et al. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5 BSAP , 1994, Cell.
[56] J D Kemp,et al. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow , 1991, The Journal of experimental medicine.
[57] M. Bustin,et al. Immunochemical analysis of the exposure of high mobility group protein 14 and 17 surfaces in chromatin. , 1990, The Journal of biological chemistry.
[58] F. Alt,et al. IgH enhancer‐mediated deregulation of N‐myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c‐myc expression. , 1989, The EMBO journal.
[59] J. McPherson,et al. A Chromosome 21 Critical Region Does Not Cause Specific Down Syndrome Phenotypes , 2022 .