Genital oedema from contact allergy to prednicarbate

Case Report A 68-year-old man, with pruritus and a burning sensation of the penis and scrotum, was treated with BrentanA cream (hydrocortisone and miconazole nitrate) and DeltacineA solution (neomycin and thimerosal), to which he developed an eczematous reaction in the genital and inquinal region. PeitelA ointment (prednicarbate) was then applied, and 3 days later, an intense oedema of the penis and scrotum with erythema and vesicles was observed. Blood and urine analyses were normal. Bacteriological and mycological cultures were negative. The patient was treated with AdventanA ointment (methylprednisolone acetonate), and the lesions disappeared completely. Patch tests were carried out with a standard series, with positive results to nickel, quinoline mix, chlorquinaldol and thimerosal. We later applied a series of 30 corticosteroids, 2% petrolatum miconazole nitrate, the excipients and medicaments used by the patient. The results are shown in Table 1.