Entropy stabilized materials [1], where the mixing of the components is driven by configurational entropy rather than formation enthalpy, are potential candidates for ultra-high temperature applications. The prediction of which compositions will form entropy stabilized materials is difficult since calculating the entropic contribution to the free energy from first principles is computationally expensive. Therefore, we have formulated a descriptor for the synthesizability of disordered materials based on the energy distribution of the thermodynamic density of states (TDOS) for an ensemble of ordered configurations generated using the AFLOW (Automatic FLOW) partial occupation (AFLOW-POCC) methodology [2,3] and calculated with DFT. This descriptor has been used to successfully predict which refractory metal carbide compositions can be experimentally synthesized as singlephase entropy stabilized materials [4].