Hepatitis C Virus Antibody Status and Survival After Renal Transplantation: Meta‐Analysis of Observational Studies

The natural history of hepatitis C virus (HCV) among patients after renal transplantation (RT) remains incompletely defined. We conducted a systematic review of the published medical literature on the impact of hepatitis C antibody status on survival of patients who received RT. We used the random effects model of DerSimonian and Laird to generate a summary estimate of the relative risk (RR) for mortality and graft loss with HCV seropositivity across the published studies.

[1]  M. Schnitzler,et al.  The Impact of Transplantation with Deceased Donor Hepatitis C‐Positive Kidneys on Survival in Wait‐Listed Long‐term Dialysis Patients , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[2]  A. Bruchfeld,et al.  Hepatitis C Infection, Time in Renal-Replacement Therapy, and Outcome after Kidney Transplantation , 2004, Transplantation.

[3]  J. Morales,et al.  The influence of hepatitis B and hepatitis C virus infection in the recipient on late renal allograft failure. , 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[4]  Y. Chiang,et al.  Impact of HCV infection on first cadaveric renal transplantation, a single center experience , 2004, Clinical transplantation.

[5]  D. Serón,et al.  Late renal allograft failure between 1990 and 1998 in Spain: A changing scenario1 , 2003, Transplantation.

[6]  L. Agodoa,et al.  Hepatitis C and renal transplantation in the era of modern immunosuppression. , 2003, Journal of the American Society of Nephrology : JASN.

[7]  J. Hoofnagle,et al.  Hepatitis C and renal disease: an update. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[8]  M. Schnitzler.  Diabetes Mellitus After Kidney Transplantation in the United States , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[9]  F. Fabrizi,et al.  Transplantation of kidneys from HCV-positive donors: a safe strategy? , 2003, Journal of nephrology.

[10]  B. Einollahi,et al.  Pretransplant hepatitis C virus infection and its effect on the post‐transplant course of living renal allograft recipients , 2003, Journal of gastroenterology and hepatology.

[11]  J. Torras,et al.  Pretransplant Interferon Prevents Hepatitis C Virus‐Associated Glomerulonephritis in Renal Allografts by HCV‐RNA Clearance , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[12]  L. Seeff,et al.  Natural history of chronic hepatitis C , 2002, Hepatology.

[13]  J. Piette,et al.  Long-term impact of renal transplantation on liver fibrosis during hepatitis C virus infection. , 2002, Gastroenterology.

[14]  L. Seeff.  Natural history of chronic hepatitis C , 2002 .

[15]  F. Fabrizi,et al.  Hepatitis C infection and the patient with end‐stage renal disease , 2002, Hepatology.

[16]  M. Olschewski,et al.  Impact of hepatitis B and C on graft loss and mortality of patients after kidney transplantation , 2002, Clinical transplantation.

[17]  Y. Shemer-Avni,et al.  Hepatitis C virus infection in renal failure patients in the absence of anti‐hepatitis C virus antibodies , 2002, Journal of viral hepatitis.

[18]  F. Locatelli,et al.  Decreased serum aminotransferase activity in patients with chronic renal failure: impact on the detection of viral hepatitis. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[19]  A. Ojo,et al.  Hepatitis C antibody status and outcomes in renal transplant recipients. , 2001, Transplantation.

[20]  J. Torras,et al.  Hepatitis C Virus Infection and de Novo Glomerular Lesions in Renal Allografts , 2001, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[21]  Chi-hung Cheng,et al.  Long-Term Impact of Hepatitis B, C Virus Infection on Renal Transplantation , 2001, American Journal of Nephrology.

[22]  A. Kirk,et al.  Hepatitis C Virus Seropositivity at the Time of Renal Transplantation in the United States: Associated Factors and Patient Survival , 2001, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[23]  G. Mosconi,et al.  Renal transplantation and HCV hepatitis: a longitudinal study. , 2001, Transplantation proceedings.

[24]  M. Gentil,et al.  Impaired kidney transplant survival in patients with antibodies to hepatitis C virus. , 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[25]  P Coriat,et al.  Impact of hepatitis B and C virus on kidney transplantation outcome , 1999, Hepatology.

[26]  A. Okuyama,et al.  Retrospective study on the impact of hepatitis C virus infection on kidney transplant patients over 20 years. , 1998, Transplantation.

[27]  C. Ponticelli,et al.  Long-term evolution of anti-HCV-positive renal transplant recipients. , 1998, Transplantation proceedings.

[28]  E. Tanaka,et al.  Prospective follow‐up study of hepatitis C virus infection in patients undergoing maintenance haemodialysis: Comparison among haemodialysis units , 1998, Journal of gastroenterology and hepatology.

[29]  P. Landais,et al.  Harmful long-term impact of hepatitis C virus infection in kidney transplant recipients. , 1998, Transplantation.

[30]  G. Vosnides,et al.  Hepatitis C in renal transplantation. , 1997, Kidney international.

[31]  C. Stehman-Breen,et al.  Association of hepatitis C virus infection with mortality and graft survival in kidney-pancreas transplant recipients. , 1997, Transplantation.

[32]  C. Schmid,et al.  Long-term follow-up of hepatitis C virus infection among organ transplant recipients: implications for policies on organ procurement. , 1997, Transplantation.

[33]  G. Ciancio,et al.  A prospective study of hepatitis C virus infection in renal allograft recipients. , 1996, Transplantation.

[34]  A. Levey,et al.  THE IMPACT OF PRETRANSPLANTATION HEPATITIS C INFECTION ON THE OUTCOME OF RENAL TRANSPLANTATION , 1995, Transplantation.

[35]  C. Schmid,et al.  A controlled study of hepatitis C transmission by organ transplantation , 1995, The Lancet.

[36]  Helen H. Lee,et al.  HEPATITIS C IS A POOR PROGNOSTIC INDICATOR IN BLACK KIDNEY TRANSPLANT RECIPIENTS , 1993, Transplantation.

[37]  C. Ynares,et al.  Impact of pretransplant hepatitis C antibody status upon long-term patient and renal allograft survival--a 5- and 10-year follow-up. , 1993, Transplantation proceedings.

[38]  C. Gil,et al.  Hepatitis C virus infection among kidney transplant recipients. , 1991, Kidney international.

[39]  R. Purcell,et al.  Interrelationship of blood transfusion, non‐A, non‐B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus , 1990, Hepatology.

[40]  M. Friedlaender,et al.  Chronic hepatitis in kidney allograft recipients , 1990, The Lancet.

[41]  F. Carnot,et al.  Chronic hepatitis in kidney allograft recipients , 1990, The Lancet.

[42]  D L Demets,et al.  Methods for combining randomized clinical trials: strengths and limitations. , 1987, Statistics in medicine.

[43]  N. Laird,et al.  Meta-analysis in clinical trials. , 1986, Controlled clinical trials.

[44]  T. Poynard,et al.  The retrieval of randomized clinical trials in liver disease from the medical literature. A comparison of MEDLARS and manual methods. , 1985, Controlled clinical trials.

[45]  F. Carnot,et al.  Severe evolution of chronic hepatitis C in renal transplantation: a case control study. , 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[46]  P. Stock,et al.  Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection. , 1995, Clinical transplantation.

[47]  G. Burke,et al.  The impact of hepatitis C virus infection on renal allograft recipients. , 1994, Kidney international.